Search Results - "Abudupataer, Mieradilijiang"
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Bioprinting a 3D vascular construct for engineering a vessel-on-a-chip
Published in Biomedical microdevices (26-12-2019)“…The organ-on-a-chip model mimics the structural and functional features of human tissues or organs and has great importance in translational research. For…”
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Aorta smooth muscle-on-a-chip reveals impaired mitochondrial dynamics as a therapeutic target for aortic aneurysm in bicuspid aortic valve disease
Published in eLife (06-09-2021)“…Background: Bicuspid aortic valve (BAV) is the most common congenital cardiovascular disease in general population and is frequently associated with the…”
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A pre-screening strategy to assess resected tumor margins by imaging cytoplasmic viscosity and hypoxia
Published in eLife (11-10-2021)“…To assure complete tumor removal, frozen section analysis is the most common procedure for intraoperative pathological assessment of resected tumor margins…”
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Aggravated myocardial infarction-induced cardiac remodeling and heart failure in histamine-deficient mice
Published in Scientific reports (08-03-2017)“…Histamine has pleiotropic pathophysiological effects, but its role in myocardial infarction (MI)-induced cardiac remodeling remains unclear. Histidine…”
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99mTc-labeled bevacizumab for detecting atherosclerotic plaque linked to plaque neovascularization and monitoring antiangiogenic effects of atorvastatin treatment in ApoE−/− mice
Published in Scientific reports (14-06-2017)“…Atherosclerotic neovascularization plays a significant role in plaque instability as it provides additional lipids and inflammatory mediators to lesions, and…”
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Ciprofloxacin exacerbates dysfunction of smooth muscle cells in a microphysiological model of thoracic aortic aneurysm
Published in JCI insight (24-01-2023)“…Ciprofloxacin use may be associated with adverse aortic events. However, the mechanism underlying the effect of ciprofloxacin on the progression of thoracic…”
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Patient-derived microphysiological model identifies the therapeutic potential of metformin for thoracic aortic aneurysm
Published in EBioMedicine (01-07-2022)“…Thoracic aortic aneurysm (TAA) is the permanent dilation of the thoracic aortic wall that predisposes patients to lethal events such as aortic dissection or…”
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Engineering a Human Pluripotent Stem Cell-Based in vitro Microphysiological System for Studying the Metformin Response in Aortic Smooth Muscle Cells
Published in Frontiers in bioengineering and biotechnology (18-03-2021)“…Aortic aneurysm is a common cardiovascular disease characterised by continuous dilation of the aorta, and this disease places a heavy burden on healthcare…”
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Construction of a high-throughput aorta smooth muscle-on-a-chip for thoracic aortic aneurysm drug screening
Published in Biosensors & bioelectronics (15-12-2022)Get full text
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Nicotinamide Mononucleotide Alleviates Angiotensin II-Induced Human Aortic Smooth Muscle Cell Senescence in a Microphysiological Model
Published in Journal of cardiovascular pharmacology (01-04-2023)“…The occurrence and development of aortic aneurysms are accompanied by senescence of human aortic smooth muscle cells (HASMCs). Because the mechanism of HASMC…”
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PM2.5 exposure exacerbates mice thoracic aortic aneurysm and dissection by inducing smooth muscle cell apoptosis via the MAPK pathway
Published in Chemosphere (Oxford) (01-02-2023)“…Air pollution is a major public health concern worldwide. Exposure to fine particulate matter (PM2.5) is closely associated with cardiovascular diseases…”
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Bibliometric analysis of the current status and trend of domestic and international research on primary cardiac malignant tumors
Published in Zhongguo Linchuang Yixue (01-10-2024)“…ObjectiveTo analyze the current state of domestic and international research on primary cardiac malignant tumor and predict its future development trends using…”
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Mechanical characterization and material modeling of ascending aortic aneurysm with different bicuspid aortic cusp fusion morphologies
Published in Journal of the mechanical behavior of biomedical materials (01-08-2022)“…Bicuspid aortic valve (BAV) is frequently associated with ascending thoracic aortic aneurysm (ATAA). Impact of cusp fusion patterns on biomechanics and…”
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Gender differences in the dissection properties of ascending thoracic aortic aneurysms
Published in Interactive cardiovascular and thoracic surgery (09-07-2022)“…Abstract OBJECTIVES Presentation, management and outcomes in the aortic dissection (AD) of ascending thoracic aortic aneurysm (ATAA) differ in gender and age…”
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Histamine deficiency facilitates coronary microthrombosis after myocardial infarction by increasing neutrophil‐platelet interactions
Published in Journal of cellular and molecular medicine (01-03-2020)“…Neutrophil‐platelet interactions are responsible for thrombosis as well as inflammatory responses following acute myocardial infarction (AMI). While histamine…”
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Risk factors associated with perioperative morbidity and mortality following isolated tricuspid valve replacement
Published in The Journal of surgical research (01-01-2018)“…Reports of isolated tricuspid valve replacement (iTVR) are relatively rare. The present study aimed to evaluate independent risk factors of perioperative…”
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A hiPSC-derived lineage-specific vascular smooth muscle cell-on-a-chip identifies aortic heterogeneity across segments
Published in Lab on a chip (28-03-2023)“…Aortic aneurysm (AA), a potentially lethal condition with the characteristic of aortic dilatation, can only be treated by surgical or endovascular procedures…”
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Hydrogel Bioink with Multilayered Interfaces Improves Dispersibility of Encapsulated Cells in Extrusion Bioprinting
Published in ACS applied materials & interfaces (28-08-2019)“…One of the challenges for extrusion bioprinting using low-viscosity bioinks is the fast gravity-driven sedimentation of cells. Cells in a hydrogel bioink that…”
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99m Tc-labeled Duramycin for detecting and monitoring cardiomyocyte death and assessing atorvastatin cardioprotection in acute myocardial infarction
Published in Chemical biology & drug design (01-02-2021)“…This study aimed to dynamically monitor myocardial cell death using Tc-Duramycin single-photon emission computed tomography/computed tomography…”
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