Search Results - "Abudara, Veronica"

Astroglial Metabolic Networks Sustain Hippocampal Synaptic Transmission by Rouach, Nathalie, Koulakoff, Annette, Abudara, Veronica, Willecke, Klaus, Giaume, Christian

“…Astrocytes provide metabolic substrates to neurons in an activity-dependent manner. However, the molecular mechanisms involved in this function, as well as its…”
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Amyloid β-induced death in neurons involves glial and neuronal hemichannels by Orellana, Juan A, Shoji, Kenji F, Abudara, Verónica, Ezan, Pascal, Amigou, Edwige, Sáez, Pablo J, Jiang, Jean X, Naus, Christian C, Sáez, Juan C, Giaume, Christian

“…The mechanisms involved in Alzheimer's disease are not completely understood and how glial cells contribute to this neurodegenerative disease remains to be…”
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Pericyte Mapping in Cerebral Slices with the Far-red Fluorophore TO-PRO-3 by Mai-Morente, Sandra P, Irigoyen, Juan P, Carriquiry, Victoria M, Marset, Virginia M, Di Doménico, Mariana, Isasi, Eugenia, Abudara, Verónica

“…This protocol describes a method for high-resolution confocal imaging of pericytes with the far-red fluorophore TO-PRO -3 Iodide 642/661 in cerebral slices of…”
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P2X7 receptors and pannexin1 hemichannels shape presynaptic transmission by Vitureira, Nathalia, Rafael, Alberto, Abudara, Verónica

“…Over the last decades, since the discovery of ATP as a transmitter, accumulating evidence has been reported about the role of this nucleotide and purinergic…”
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Activated microglia impairs neuroglial interaction by opening Cx43 hemichannels in hippocampal astrocytes by Abudara, Verónica, Roux, Lisa, Dallérac, Glenn, Matias, Isabelle, Dulong, Jérôme, Mothet, Jean Pierre, Rouach, Nathalie, Giaume, Christian

“…Glia plays an active role in neuronal functions and dysfunctions, some of which depend on the expression of astrocyte connexins, the gap junction channel and…”
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Glial Cx43 hemichannels and neuronal Panx1 hemichannels and P2X7 receptors orchestrate presynaptic homeostatic plasticity by Rafael, Alberto, Tizzoni, Marina, Justet, Cristian, Cairus, Andrea, Abudara, Verónica, Vitureira, Nathalia

“…The emerging role of glial cells in modulating neuronal excitability and synaptic strength is a growing field in neuroscience. In recent years, a pivotal role…”
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Gestational and Lactational Iron Deficiency Anemia Impairs Myelination and the Neurovascular Unit in Infant Rats by Isasi, Eugenia, Figares, Martin, Abudara, Verónica, Olivera-Bravo, Silvia

“…Iron deficiency anemia is a prevalent health problem among pregnant women and infants, particularly in the developing countries that causes brain development…”
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Glial ATP and Large Pore Channels Modulate Synaptic Strength in Response to Chronic Inactivity by Rafael, Alberto, Cairus, Andrea, Tizzoni, Marina, Abudara, Verónica, Vitureira, Nathalia

“…A key feature of neurotransmission is its ability to adapt to changes in neuronal environment, which is essential for many brain functions. Homeostatic…”
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Glutaric Acid Affects Pericyte Contractility and Migration: Possible Implications for GA-I Pathogenesis by Isasi, Eugenia, Korte, Nils, Abudara, Verónica, Attwell, David, Olivera-Bravo, Silvia

“…Glutaric acidemia I (GA-I) is an inherited neurometabolic childhood disease characterized by bilateral striatal neurodegeneration upon brain accumulation of…”
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Synaptic Functions of Hemichannels and Pannexons: A Double-Edged Sword by Abudara, Verónica, Retamal, Mauricio A, Del Rio, Rodrigo, Orellana, Juan A

“…The classical view of synapses as the functional contact between presynaptic and postsynaptic neurons has been challenged in recent years by the emerging…”
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FGF-1 induces ATP release from spinal astrocytes in culture and opens pannexin and connexin hemichannels by Garré, Juan M., Retamal, Mauricio A., Cassina, Patricia, Barbeito, Luis, Bukauskas, Feliksas F., Sáez, Juan C., Bennett, Michael V. L., Abudara, Verónica

“…Spinal astrocytes are coupled by connexin (Cx) gap junctions and express pannexin 1 (Px1) and purinergic receptors. Fibroblast growth factor 1 (FGF-1), which…”
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A nuclear fluorescent dye identifies pericytes at the neurovascular unit by Mai‐Morente, Sandra P., Marset, Virginia M., Blanco, Fabiana, Isasi, Eugenia E., Abudara, Verónica

“…Perivascular pericytes are key regulators of the blood–brain barrier, vascular development, and cerebral blood flow. Deciphering pericyte roles in health and…”
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Remembrances of Dr. Michael V.L. Bennett by Iberoamerican Colleagues and Friends by Abudara, Verónica, Araneda, Ricardo C., Barrio, Luis, Berthoud, Viviana M., Contreras, Jorge E., Eugenín, Eliseo, Lerma, Juan, Orellana, Juan A., Palacios-Prado, Nicolás, Pérez-Armendariz, Elia Martha, Retamal, Mauricio A., Sáez, Juan C.

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The connexin43 mimetic peptide Gap19 inhibits hemichannels without altering gap junctional communication in astrocytes by Abudara, Verónica, Bechberger, John, Freitas-Andrade, Moises, De Bock, Marijke, Wang, Nan, Bultynck, Geert, Naus, Christian C, Leybaert, Luc, Giaume, Christian

“…In the brain, astrocytes represent the cellular population that expresses the highest amount of connexins (Cxs). This family of membrane proteins is the…”
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Behavior of Junction Channels Between Rat Glomus Cells During Normoxia and Hypoxia by Abudara, Veronica, Jiang, R. G, Eyzaguirre, C

“…  1 Department of Physiology, University of Utah School of Medicine, Salt Lake City, Utah 84108-1297; and   2 Department of Physiology, Facultad de Medicina,…”
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Connexin 30 sets synaptic strength by controlling astroglial synapse invasion by Pannasch, Ulrike, Freche, Dominik, Dallérac, Glenn, Ghézali, Grégory, Escartin, Carole, Ezan, Pascal, Cohen-Salmon, Martine, Benchenane, Karim, Abudara, Veronica, Dufour, Amandine, Lübke, Joachim H R, Déglon, Nicole, Knott, Graham, Holcman, David, Rouach, Nathalie

“…Astrocytes provide essential support for and modulate synaptic transmission between neurons. Here the authors show that non-channel functions of connexin 30, a…”
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Endogenous presynaptic nitric oxide supports an anterograde signaling in the central nervous system by Fernández‐Alvarez, Adriana, Gómez‐Sena, Leonel, Fabbiani, María Gabriela, Budelli, Ruben, Abudara, Verónica

“…J. Neurochem. (2011) 118, 546–557. The source size and density determine the extent of nitric oxide (NO) diffusion which critically influences NO signaling. In…”
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Mechanical sensitivity of carotid body glomus cells by Abudara, Veronica, Eyzaguirre, Carlos

“…Abstract Cultured glomus cells from rat carotid bodes were prepared for optical studies of intracellular calcium using the Fura-2 dye. The baseline calcium had…”
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Nitric Oxide as an Anterograde Neurotransmitter in the Trigeminal Motor Pool by Abudara, Veronica, Alvarez, Adriana Fernandez, Chase, Michael H, Morales, Francisco R

“…  1 Departamento de Fisiología, Facultad de Medicina, Montevideo-Uruguay 11800; and   2 Department of Physiology and the Brain Research Institute, UCLA School…”
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Connexin-based channels in astrocytes: how to study their properties by Giaume, Christian, Orellana, Juan A, Abudara, Verónica, Sáez, Juan C

“…A typical feature of astrocytes is their high level of connexin expression. These membrane proteins constitute the molecular basis of two types of channels:…”
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