Scanning electron microscopy of molluscum contagiosum

Molluscum contagiosum is a disease caused by a poxvirus. It is more prevalent in children up to 5 years of age. There is a second peak of incidence in young adults. In order to examine its ultrastructure, three lesions were curetted without disruption, cut transversely with a scalpel, and routinely...

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Bibliographic Details
Published in:	Anais brasileiros de dermatología Vol. 88; no. 1; pp. 90 - 93
Main Authors:	Almeida, Jr, Hiram Larangeira de, Abuchaim, Martha Oliveira, Schneide, Maiko Abel, Marques, Leandra, Castro, Luis Antônio Suíta de
Format:	Journal Article
Language:	English
Published:	Brazil Sociedade Brasileira de Dermatologia 01-01-2013
Subjects:	DERMATOLOGY Dermatopathology Humans Microscopy, Electron, Scanning Molluscum Contagiosum - pathology Microscopy, electron, scanning Microscopia eletrônica de varredura Vírus do molusco contagioso Molusco contagioso Molluscum contagiosum virus Molluscum contagiosum
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Summary:	Molluscum contagiosum is a disease caused by a poxvirus. It is more prevalent in children up to 5 years of age. There is a second peak of incidence in young adults. In order to examine its ultrastructure, three lesions were curetted without disruption, cut transversely with a scalpel, and routinely processed for scanning electron microscopy (SEM). The oval structure of molluscum contagiosum could be easily identified. In its core, there was a central umbilication and just below this depression, there was a keratinized tunnel. Under higher magnification, a proliferation similar to the epidermis was seen. Moreover, there were areas of cells disposed like a mosaic. Under higher magnification, rounded structures measuring 0.4 micron could be observed at the end of the keratinized tunnel and on the surface of the lesion.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0365-0596 1806-4841 1806-4841 0365-0596
DOI:	10.1590/S0365-05962013000100011