Search Results - "Abubaker, Jehad"

The Role of Lipid Metabolism in COVID-19 Virus Infection and as a Drug Target by Abu-Farha, Mohamed, Thanaraj, Thangavel Alphonse, Qaddoumi, Mohammad G, Hashem, Anwar, Abubaker, Jehad, Al-Mulla, Fahd

“…The current Coronavirus disease 2019 or COVID-19 pandemic has infected over two million people and resulted in the death of over one hundred thousand people at…”
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The role of Gut Microbiota in the development of obesity and Diabetes by Baothman, Othman A, Zamzami, Mazin A, Taher, Ibrahim, Abubaker, Jehad, Abu-Farha, Mohamed

“…Obesity and its associated complications like type 2 diabetes (T2D) are reaching epidemic stages. Increased food intake and lack of exercise are two main…”
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ANGPTL8 (betatrophin) role in diabetes and metabolic diseases by Abu‐Farha, Mohamed, Abubaker, Jehad, Tuomilehto, Jaakko

“…Summary Diabetes is a major disease worldwide that is reaching epidemic levels. Its increased prevalence as well as its association with a high number of…”
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Spexin as an indicator of beneficial effects of exercise in human obesity and diabetes by Khadir, Abdelkrim, Kavalakatt, Sina, Madhu, Dhanya, Devarajan, Sriraman, Abubaker, Jehad, Al-Mulla, Fahd, Tiss, Ali

“…Spexin is a novel neuropeptide playing an emerging role in metabolic diseases such as obesity and diabetes via involvement in energy homeostasis and food…”
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mTOR: Its Critical Role in Metabolic Diseases, Cancer, and the Aging Process by Marafie, Sulaiman K, Al-Mulla, Fahd, Abubaker, Jehad

“…The mammalian target of rapamycin (mTOR) is a pivotal regulator, integrating diverse environmental signals to control fundamental cellular functions, such as…”
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Impact of Diabetes in Patients Diagnosed With COVID-19 by Abu-Farha, Mohamed, Al-Mulla, Fahd, Thanaraj, Thangavel Alphonse, Kavalakatt, Sina, Ali, Hamad, Abdul Ghani, Mohammed, Abubaker, Jehad

“…COVID-19 is a disease caused by the coronavirus SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2), known as a highly contagious disease, currently…”
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PKD1 Duplicated regions limit clinical Utility of Whole Exome Sequencing for Genetic Diagnosis of Autosomal Dominant Polycystic Kidney Disease by Ali, Hamad, Al-Mulla, Fahd, Hussain, Naser, Naim, Medhat, Asbeutah, Akram M., AlSahow, Ali, Abu-Farha, Mohamed, Abubaker, Jehad, Al Madhoun, Ashraf, Ahmad, Sajjad, Harris, Peter C.

“…Autosomal dominant polycystic kidney disease (ADPKD) is an inherited monogenic renal disease characterised by the accumulation of clusters of fluid-filled…”
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The Two Faces of ACE2: The Role of ACE2 Receptor and Its Polymorphisms in Hypertension and COVID-19 by Bosso, Mira, Thanaraj, Thangavel Alphonse, Abu-Farha, Mohamed, Alanbaei, Muath, Abubaker, Jehad, Al-Mulla, Fahd

“…The mechanism for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection requires the binding of the virus to the angiotensin-converting enzyme…”
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Investigating the Role of Myeloperoxidase and Angiopoietin-like Protein 6 in Obesity and Diabetes by Qaddoumi, Mohammad G., Alanbaei, Muath, Hammad, Maha M., Al Khairi, Irina, Cherian, Preethi, Channanath, Arshad, Thanaraj, Thangavel Alphonse, Al-Mulla, Fahd, Abu-Farha, Mohamed, Abubaker, Jehad

“…Myeloperoxidase (MPO) is positively associated with obesity and diet-induced insulin resistance. Angiopoietin-like protein 6 (ANGPTL6) regulates metabolic…”
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Investigating the Relationship between Obstructive Sleep Apnoea, Inflammation and Cardio-Metabolic Diseases by Alterki, Abdulmohsen, Abu-Farha, Mohamed, Al Shawaf, Eman, Al-Mulla, Fahd, Abubaker, Jehad

“…Obstructive sleep apnoea (OSA) is a prevalent underdiagnosed disorder whose incidence increases with age and weight. Uniquely characterised by frequent…”
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South African (501Y.V2) and the United Kingdom (B.1.1.7) SARS-CoV-2 Spike (S) Protein Variants Demonstrate a Higher Binding Affinity to ACE2 by Mohammad, Anwar, Abubaker, Jehad, Al-Mulla, Fahd

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the lower respiratory tract by binding to angiotensin-converting enzyme 2 (ACE2) via its…”
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Higher binding affinity of furin for SARS-CoV-2 spike (S) protein D614G mutant could be associated with higher SARS-CoV-2 infectivity by Mohammad, Anwar, Alshawaf, Eman, Marafie, Sulaiman K., Abu-Farha, Mohamed, Abubaker, Jehad, Al-Mulla, Fahd

“…•The G clade 23403A>G mutation on the spike glycoprotein (S protein) encodes a virulent strain of SARS-CoV-2.•The D614G substitution causes the loss of a…”
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Urocortin 3 overexpression reduces ER stress and heat shock response in 3T3-L1 adipocytes by Kavalakatt, Sina, Khadir, Abdelkrim, Madhu, Dhanya, Koistinen, Heikki A., Al-Mulla, Fahd, Tuomilehto, Jaakko, Abubaker, Jehad, Tiss, Ali

“…The neuropeptide urocortin 3 (UCN3) has a beneficial effect on metabolic disorders, such as obesity, diabetes, and cardiovascular disease. It has been reported…”
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Circulating ANGPTL8/Betatrophin Is Increased in Obesity and Reduced after Exercise Training by Abu-Farha, Mohamed, Sriraman, Devarajan, Cherian, Preethi, AlKhairi, Irina, Elkum, Naser, Behbehani, Kazem, Abubaker, Jehad

“…ANGPTL8 is a liver and adipose tissue produced protein that regulates the level of triglyceride in plasma as well as glucose homeostasis. This study was…”
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Robust Antibody Levels in Both Diabetic and Non-Diabetic Individuals After BNT162b2 mRNA COVID-19 Vaccination by Ali, Hamad, Alterki, Abdulmohsen, Sindhu, Sardar, Alahmad, Barrak, Hammad, Maha, Al-Sabah, Salman, Alghounaim, Mohammad, Jamal, Mohammad H, Aldei, Ali, Mairza, Mohammad J, Husain, Maitham, Deverajan, Sriraman, Ahmad, Rasheed, Cherian, Preethi, Alkhairi, Irina, Alkandari, Abdullah, Abubaker, Jehad, Abu-Farha, Mohamed, Al-Mulla, Fahd

“…The emergence of effective vaccines for COVID-19 has been welcomed by the world with great optimism. Given their increased susceptibility to COVID-19, the…”
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Clinical characteristics of coronavirus disease 2019 (COVID-19) patients in Kuwait by Alshukry, Abdullah, Ali, Hamad, Ali, Yaseen, Al-Taweel, Talal, Abu-Farha, Mohammad, AbuBaker, Jehad, Devarajan, Sriraman, Dashti, Ali A, Bandar, Ali, Taleb, Hessah, Al Bader, Abdullah, Aly, Nasser Y, Al-Ozairi, Ebaa, Al-Mulla, Fahd, Bu Abbas, Mohammad

“…This is a retrospective single-center study of 417 consecutive patients with coronavirus disease 2019 (COVID-19) admitted to Jaber Al-Ahmad Hospital in Kuwait…”
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Editorial: Diabetes in the Middle East by Abu-Farha, Mohamed, Tuomilehto, Jaakko, Abubaker, Jehad

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Remdesivir MD Simulations Suggest a More Favourable Binding to SARS-CoV-2 RNA Dependent RNA Polymerase Mutant P323L Than Wild-Type by Mohammad, Anwar, Al-Mulla, Fahd, Wei, Dong-Qing, Abubaker, Jehad

“…SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) protein is the target for the antiviral drug Remdesivir (RDV). With RDV clinical trials on COVID-19 patients…”
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Correlation of circulating ANGPTL5 levels with obesity, high sensitivity C-reactive protein and oxidized low-density lipoprotein in adolescents by Hammad, Maha M., Abu-Farha, Mohamed, Al-Taiar, Abdullah, Alam-Eldin, Nada, Al-Sabah, Reem, Shaban, Lemia, Al-Mulla, Fahd, Abubaker, Jehad, Rahman, Abdur

“…Angiopoietin-like proteins (ANGPTL) is a family of eight members known to play an important role in metabolic diseases. Of these, ANGPTL5 is suggested to…”
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Editorial: Pharmacology and treatment methods for NAFLD in the context of diabetes by Abu-Farha, Mohamed, Lee, Yong-ho, Abubaker, Jehad

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