Search Results - "Abu‐Risha, Sally E."

Targeting MDR‐1 gene expression, BAX/BCL2, caspase‐3, and Ki‐67 by nanoencapsulated imatinib and hesperidin to enhance anticancer activity and ameliorate cardiotoxicity by El‐Sisi, Alaa E., Sokkar, Samia S., Ibrahim, Hanaa A., Hamed, Mohamed F., Abu‐Risha, Sally E.

“…There is a great demand to introduce new approaches into cancer treatment field due to incidence of increased breast cancer all over the world. The current…”
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Zinc Supplementation in Preterm Neonates with Jaundice: Is it Beneficial? by Elfarargy, Mohamed S, Al-Ashmawy, Ghada M, Abu-Risha, Sally E, Khattab, Haidy

“…Neonatal jaundice is a common neonatal disease that has adverse effects on neonates, especially preterm neonates, when indirect bilirubin level is adequately…”
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The potential beneficial effects of sildenafil and diosmin in experimentally-induced gastric ulcer in rats by El-Sisi, Alaa E., Sokar, Samia S., Abu-Risha, Sally E., Khira, Doaa Y.

“…research in the treatment of gastric ulcer has involved the investigation of protective drugs. These drugs may be used as adjacent therapy with the traditional…”
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Protective role of irbesartan against cyclophosphamide-induced testicular damage in rats via up-regulating PPAR-γ signaling and ameliorating NF-κB/NLRP3/IL-18 inflammatory axis by Abu-Risha, Sally E., Mousa, Mai A., Elsisi, Alaa E.

“…Cancer and its therapies can impact fertility in various ways, and therefore a growing number of cancer survivors face fertility as a significant concern. The…”
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Combined carvacrol and cilostazol ameliorate ethanol-induced liver fibrosis in rats: Possible role of SIRT1/Nrf2/HO-1 pathway by Abu-Risha, Sally E., Sokar, Samia S., Elbohoty, Heba R., Elsisi, Alaa E.

“…[Display omitted] •Liver fibrosis is one of the most widespread hepatic diseases in the world.•Carvacrol or cilostazol ameliorate alcoholic liver fibrosis…”
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Donepezil and quercetin alleviate valproate-induced testicular oxidative stress, inflammation and apoptosis: Imperative roles of AMPK/SIRT1/ PGC-1α and p38-MAPK/NF-κB/ IL-1β signaling cascades by Abu-Risha, Sally E., Sokar, Samia S., Elzorkany, Kawthar E., Elsisi, Alaa E.

“…•VPA administration negatively impacts the overall testicular function.•Donepezil or quercetin effectively mitigates VPA-induced testicular toxicity.•The…”
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Eicosapentaenoic acid mitigates ulcerative colitis-induced by acetic acid through modulation of NF-κB and TGF-β/ EGFR signaling pathways by El Mahdy, Raghda N., Nader, Manar A., Helal, Manar G., Abu-Risha, Sally E., Abdelmageed, Marwa E.

“…Ulcerative colitis (UC) is a chronic mucosal inflammation of the large intestine that mostly affects the rectum and colon. The absence of safe and effective…”
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Potential effects of carbon monoxide donor and its nanoparticles on experimentally induced gastric ulcer in rats by Elsisi, Alaa E., Mekky, Esraa F., Abu-Risha, Sally E.

“…The prevalence of gastric ulcers is increasing worldwide, especially those brought on by non-steroidal anti-inflammatory drugs (NSAIDS), so prevention is…”
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Tiron ameliorates acetic acid-induced colitis in rats: Role of TGF-β/EGFR/PI3K/NF-κB signaling pathway by El Mahdy, Raghda N., Nader, Manar A., Helal, Manar G., Abu-Risha, Sally E., Abdelmageed, Marwa E.

“…[Display omitted] •Tiron exerted a protective effect against AA- induced colitis in rats.•Tiron attenuated oxidative stress (↑SOD, GSH, TAC and ↓MDA).•Tiron…”
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LC-MS/MS metabolomics profiling of Glechoma hederacea L. methanolic extract; in vitro antimicrobial and in vivo with in silico wound healing studies on Staphylococcus aureus infected rat skin wound by El-Aasr, Mona, Nohara, Toshihiro, Ikeda, Tsuyushi, Abu-Risha, Sally E, Elekhnawy, Engy, Tawfik, Haytham O, Shoeib, Nagwa, Attia, Ghada

“…LC-MS/MS analysis of L. methanolic extract (GHME), revealed the identification of 25 metabolites. Ursolic acid , 2 -hydroxyursolic acid or corosolic acid , 2…”
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Enhanced anticancer activity of combined treatment of imatinib and dipyridamole in solid Ehrlich carcinoma-bearing mice by El-Sisi, Alaa E., Sokar, Samia S., Ibrahim, Hanaa A., Abu-Risha, Sally E.

“…The current study was designed to evaluate potential enhancement of the anticancer activity of imatinib mesylate (IM) with dipyridamole (DIP) and to…”
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Comparative study between effects of ginkgo biloba extract and extract loaded on gold nanoparticles on hepatotoxicity induced by potassium bromate by Osman, Amr S., Abu-Risha, Sally E., Bakr, Samaa M., Altyar, Ahmed E., Fayad, Eman, EL-Sawi, Mamdouh R., EL-Kholy, Wafaa M.

“…In human organs, potassium bromate (KBrO3) produces toxicity. The main causes of KBrO3 hepatotoxicity are the formation of reactive oxygen species (ROS) and…”
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Oxamate potentiates taxol chemotherapeutic efficacy in experimentally-induced solid ehrlich carcinoma (SEC) in mice by El-Sisi, Alaa E., Sokar, Samia S., Abu-Risha, Sally E., El-Mahrouk, Sara R.

“…Several human cancers including the breast display elevated expression of Lactate dehydrogenase-A (LDH-A), the enzyme that converts pyruvate to lactate and…”
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Combination of tadalafil and diltiazem attenuates renal ischemia reperfusion-induced acute renal failure in rats by El-Sisi, Alaa E, Sokar, Samia S, Abu-Risha, Sally E, Ibrahim, Hanaa A

“…Abstract Life threatening conditions characterized by renal ischemia/reperfusion (RIR) such as kidney transplantation, partial nephrectomy, renal artery…”
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Potassium bromate-induced nephrotoxicity and potential curative role of metformin loaded on gold nanoparticles by Abdel-Latif, Ahmed S, Abu-Risha, Sally E, Bakr, Samaa M, EL-Kholy, Wafaa M, EL-Sawi, Mamdouh R

“…Potassium bromate (KBrO3) is classified by the International Agency for Research on Cancer as a carcinogenic compound, where it causes renal tumors. The…”
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PPARγ-dependent anti-tumor and immunomodulatory actions of pioglitazone by El-Sisi, Alaa E, Sokar, Samia S, Salem, Tarek A, Abu Risha, Sally E

“…Peroxisome proliferator-activated receptor-γ (PPARγ) has been reported to play important roles in carcinogenesis. The current study was carried out to assess…”
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Role of cysteinyl leukotriene receptor-1 antagonists in treatment of experimentally induced mammary tumor: Does montelukast modulate antitumor and immunosuppressant effects of doxorubicin? by El-Sisi, Alaa El-Din E, Sokar, Samia S, Salem, Tarek A, Abu Risha, Sally E

“…It has been reported that a leukotriene (LT)-D4 receptor (i.e. cysteinyl LT1 receptor; CysLT1R) has an important role in carcinogenesis. The current study was…”
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Metformin alleviates inflammation in oxazolone induced ulcerative colitis in rats: plausible role of sphingosine kinase 1/sphingosine 1 phosphate signaling pathway by El-Mahdy, Nageh Ahmed, El-Sayad, Magda El-Sayed, El-Kadem, Aya Hassan, Abu-Risha, Sally EL-Sayed

“…Ulcerative colitis (UC) is a chronic inflammatory bowel disease that is associated with high sphingosine kinase 1(SPHK1) expression in the colon, however its…”
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Tissue distribution, placental transfer and excretion of silver nanoparticles in pregnant rats after a single oral dose by Abdel-Halim, Khaled Y, Salim, Elsayed I, Abdel-Latif, Ahmed S, Abu-Risha, Sally E

“…A quantitative assessment of silver nanoparticles (AgNPs) in fluids and some organs of pregnant rats as well as their fetal blood were carried out in this…”
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Chitosan coated lipid carriers as nanoplatform for repurposed anti-breast cancer activity of niclosamide by Elkholy, Nancy E., Sultan, Amal A., Abu-Risha, Sally E., El Maghraby, Gamal M.

“…Drug repurposing is promising strategy with niclosamide showing encouraging results against breast cancer. However, niclosamide hydrophobicity limits its oral…”
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