Search Results - "Abtahi, Dean"

RAX, the PKR activator, sensitizes cells to inflammatory cytokines, serum withdrawal, chemotherapy, and viral infection by Bennett, Richard L., Blalock, William L., Abtahi, Dean M., Pan, Yu, Moyer, Sue A., May, W. Stratford

“…While the interferon (IFN)–inducible double-stranded RNA (dsRNA)–dependent protein kinase PKR is reported to initiate apoptosis in some instances, the…”
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RAX, the PKR activator, sensitizes cells to inflammatory cytokines, semm withdrawal, chemotherapy, and viral infection by BENNETT, Richard L, BLALOCK, William L, ABTAHI, Dean M, YU PAN, MOYER, Sue A, MAY, W. Stratford

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Targeting Src- Family Kinase Activation and Downstream Molecular Events To Overcome MM Cell Growth, Survival, and Drug- Resistance by Podar, Klaus, Tai, Yu-Tzu, Abtahi, Dean, Raab, Marc S., Yasui, Hiroshi, Ishitsuka, Kenji, Shiraishi, Norihiko, Catley, Laurence P., Sattler, Martin, Raje, Noopur, Hideshima, Teru, Chauhan, Dharminder

“…IL-6 induces growth and survival factor in multiple myeloma (MM) via ERK and Akt signaling cascades. Our recent studies difined early signaling events…”
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The PKC- Inhibitor Enzastaurin Inhibits MM Cell Growth, Survival and Migration in the Bone Marrow Microenvironment by Podar, Klaus, Raab, Marc S., Abtahi, Dean, Tai, Yu-Tzu, Lin, Boris, Munshi, Nikhil C., Hideshima, Teru, Chauhan, Dharminder, Anderson, Kenneth C.

“…Members of the protein kinase C (PKC) family of serine- threonine protein kinases mediate multiple physiological functions including differentiation, growth…”
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Up-Regulation of c-Jun contributes to the Induction of Apoptosis by Adaphostin in Human Multiple Myeloma Cells by Podar, Klaus, Tonon, Giovanni, Raab, Marc S., Sattler, Martin, Abtahi, Dean, Tai, Yu-Tzu, LeGouill, Steven, Ishitsuka, Kenji, Yasui, Hiroshi, Depinho, Ron A., Hideshima, Teru, Chauhan, Dharminder, Anderson, Kenneth C.

“…Adaphostin (NCI, Bethesda, MD) has been examined as an alternative to the 2-phenylaminopyrimidine derivate imatinib mesylate, with remarkable efficacy in the…”
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