Search Results - "Abshiru, Nebiyu A"

Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas by Piunti, Andrea, Hashizume, Rintaro, Morgan, Marc A, Bartom, Elizabeth T, Horbinski, Craig M, Marshall, Stacy A, Rendleman, Emily J, Ma, Quanhong, Takahashi, Yoh-hei, Woodfin, Ashley R, Misharin, Alexander V, Abshiru, Nebiyu A, Lulla, Rishi R, Saratsis, Amanda M, Kelleher, Neil L, James, C David, Shilatifard, Ali

“…Nucleosomes containing mutant K27M histones in diffuse intrinsic pediatric gliomas (DIPG) exclude PRC2 binding and recruit BET bromodomain proteins; however,…”
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Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability by Rickels, Ryan, Herz, Hans-Martin, Sze, Christie C, Cao, Kaixiang, Morgan, Marc A, Collings, Clayton K, Gause, Maria, Takahashi, Yoh-hei, Wang, Lu, Rendleman, Emily J, Marshall, Stacy A, Krueger, Annika, Bartom, Elizabeth T, Piunti, Andrea, Smith, Edwin R, Abshiru, Nebiyu A, Kelleher, Neil L, Dorsett, Dale, Shilatifard, Ali

“…Ali Shilatifard and colleagues generate Drosophila lines expressing catalytically deficient Trr, which normally deposits H3K4me1 at enhancers. Trr mutants…”
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A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation by Morgan, Marc A J, Rickels, Ryan A, Collings, Clayton K, He, Xiaolin, Cao, Kaixiang, Herz, Hans-Martin, Cozzolino, Kira A, Abshiru, Nebiyu A, Marshall, Stacy A, Rendleman, Emily J, Sze, Christie C, Piunti, Andrea, Kelleher, Neil L, Savas, Jeffrey N, Shilatifard, Ali

“…Histone H3 Lys4 (H3K4) methylation is a chromatin feature enriched at gene -regulatory sequences such as promoters and enhancers. Here we identify an…”
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Targeted detection and quantitation of histone modifications from 1,000 cells by Abshiru, Nebiyu A, Sikora, Jacek W, Camarillo, Jeannie M, Morris, Juliette A, Compton, Philip D, Lee, Tak, Neelamraju, Yaseswini, Haddox, Samuel, Sheridan, Caroline, Carroll, Martin, Cripe, Larry D, Tallman, Martin S, Paietta, Elisabeth M, Melnick, Ari M, Thomas, Paul M, Garrett-Bakelman, Francine E, Kelleher, Neil L

“…Histone post-translational modifications (PTMs) create a powerful regulatory mechanism for maintaining chromosomal integrity in cells. Histone acetylation and…”
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Stability of histone post-translational modifications in samples derived from liver tissue and primary hepatic cells by Gruppuso, Philip A, Boylan, Joan M, Zabala, Valerie, Neretti, Nicola, Abshiru, Nebiyu A, Sikora, Jacek W, Doud, Emma H, Camarillo, Jeannie M, Thomas, Paul M, Kelleher, Neil L, Sanders, Jennifer A

“…Chromatin structure, a key contributor to the regulation of gene expression, is modulated by a broad array of histone post-translational modifications (PTMs)…”
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A synthetic biology approach to probing nucleosome symmetry by Ichikawa, Yuichi, Connelly, Caitlin F, Appleboim, Alon, Miller, Thomas Cr, Jacobi, Hadas, Abshiru, Nebiyu A, Chou, Hsin-Jung, Chen, Yuanyuan, Sharma, Upasna, Zheng, Yupeng, Thomas, Paul M, Chen, Hsuiyi V, Bajaj, Vineeta, Müller, Christoph W, Kelleher, Neil L, Friedman, Nir, Bolon, Daniel Na, Rando, Oliver J, Kaufman, Paul D

“…The repeating subunit of chromatin, the nucleosome, includes two copies of each of the four core histones, and several recent studies have reported that…”
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USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia by Jin, Qi, Martinez, Carlos A, Arcipowski, Kelly M, Zhu, Yixing, Gutierrez-Diaz, Blanca T, Wang, Kenneth K, Johnson, Megan R, Volk, Andrew G, Wang, Feng, Wu, Jian, Grove, Charles, Wang, Hui, Sokirniy, Ivan, Thomas, Paul M, Goo, Young Ah, Abshiru, Nebiyu A, Hijiya, Nobuko, Peirs, Sofie, Vandamme, Niels, Berx, Geert, Goosens, Steven, Marshall, Stacy A, Rendleman, Emily J, Takahashi, Yoh-Hei, Wang, Lu, Rawat, Radhika, Bartom, Elizabeth T, Collings, Clayton K, Van Vlierberghe, Pieter, Strikoudis, Alexandros, Kelly, Stephen, Ueberheide, Beatrix, Mantis, Christine, Kandela, Irawati, Bourquin, Jean-Pierre, Bornhauser, Beat, Serafin, Valentina, Bresolin, Silvia, Paganin, Maddalena, Accordi, Benedetta, Basso, Giuseppe, Kelleher, Neil L, Weinstock, Joseph, Kumar, Suresh, Crispino, John D, Shilatifard, Ali, Ntziachristos, Panagiotis

“…T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive disease, affecting children and adults. Chemotherapy treatments show high response rates but have…”
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Coupling Fluorescence-Activated Cell Sorting and Targeted Analysis of Histone Modification Profiles in Primary Human Leukocytes by Camarillo, Jeannie M., Swaminathan, Suchitra, Abshiru, Nebiyu A., Sikora, Jacek W., Thomas, Paul M., Kelleher, Neil L.

“…Histone posttranslational modifications (PTMs) are essential for regulating chromatin and maintaining gene expression throughout cell differentiation. Despite…”
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Coupling Fluorescence-Activated Cell Sorting and Targeted Analysis of Histone Modification Profiles in Primary Human Leukocytes by Camarillo, Jeannie M, Swaminathan, Suchitra, Abshiru, Nebiyu A, Sikora, Jacek W, Thomas, Paul M, Kelleher, Neil L

“…Histone posttranslational modifications (PTMs) are essential for regulating chromatin and maintaining gene expression throughout cell differentiation. Despite…”
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