Search Results - "Abrignani, S."

The CD4-centered universe of human T cell subsets by Geginat, J, Paroni, M, Facciotti, F, Gruarin, P, Kastirr, I, Caprioli, F, Pagani, M, Abrignani., S

“…Highlights • Continuous exposure to pathogens generates complex human T cell pools. • T cell subsets are classified by cytokine production and tissue…”
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IL-10 producing regulatory and helper T-cells in systemic lupus erythematosus by Geginat, J., Vasco, M., Gerosa, M., Tas, S.W., Pagani, M., Grassi, F., Flavell, R.A., Meroni, Pl, Abrignani, S.

“…•IL-10 has a dual role in immune responses.•IL-10 is increased in lupus, promotes autoantibody production and is evaluated as a therapeutic target in SLE…”
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Why is it so difficult to develop a hepatitis C virus preventive vaccine? by Zingaretti, C., De Francesco, R., Abrignani, S.

“…With an estimated 3% of the world’s population chronically infected, hepatitis C virus (HCV) represents a major health problem for which an efficient…”
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Evidence for a pathogenic role of extrafollicular, IL-10–producing CCR6⁺B helper T cells in systemic lupus erythematosus by Facciotti, F., Larghi, P., Bosotti, R., Vasco, C., Gagliani, N., Cordiglierif, C., Mazzarag, S., Ranzani, V., Rottoli, E., Curti, S., Penatti, A., Karnani, B., Kobayashi, Y., Crosti, M., Bombaci, M., van Hamburg, J. P., Rossetti, G., Gualtierotti, R., Gerosa, M., Gatti, S., Torretta, S., Pignataro, L., Tas, S. W., Abrignani, S., Pagani, M., Grassi, F., Meroni, P. L., Flavell, R. A., Geginat, J.

“…Interleukin 10 (IL-10) is an antiinflammatory cytokine, but also promotes B cell responses and plays a pathogenic role in systemic lupus erythematosus (SLE)…”
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Repression of miR-31 by BCL6 stabilizes the helper function of human follicular helper T cells by Ripamonti, A., Provasi, E., Lorenzo, M., De Simone, M., Ranzani, V., Vangelisti, S., Curti, S., Bonnal, R. J. P., Pignataro, L., Torretta, S., Geginat, J., Rossetti, G., Pagani, M., Abrignani, S.

“…Follicular helper T cells (TFHs) are a key component of adaptive immune responses as they help antibody production by B cells. Differentiation and function of…”
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NS5A inhibitors impair NS5A-phosphatidylinositol 4-kinase IIIα complex formation and cause a decrease of phosphatidylinositol 4-phosphate and cholesterol levels in hepatitis C virus-associated membranes by Reghellin, V, Donnici, L, Fenu, S, Berno, V, Calabrese, V, Pagani, M, Abrignani, S, Peri, F, De Francesco, R, Neddermann, P

“…The hepatitis C virus (HCV) nonstructural (NS) protein 5A is a multifunctional protein that plays a central role in viral replication and assembly. Antiviral…”
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HCV E1E2-MF59 vaccine in chronic hepatitis C patients treated with PEG-IFNα2a and Ribavirin: a randomized controlled trial by Colombatto, P., Brunetto, M. R., Maina, A. M., Romagnoli, V., Almasio, P., Rumi, M. G., Ascione, A., Pinzello, G., Mondelli, M., Muratori, L., Rappuoli, R., Rosa, D., Houghton, M., Abrignani, S., Bonino, F.

“…Summary Hepatitis C virus (HCV) vaccines may be able to increase viral clearance in combination with antiviral therapy. We analysed viral dynamics and…”
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HCV E1E2-MF59 vaccine in chronic hepatitis C patients treated with PEG-IFN alpha 2a and Ribavirin: a randomized controlled trial by Colombatto, P, Brunetto, M R, Maina, A M, Romagnoli, V, Almasio, P, Rumi, M G, Ascione, A, Pinzello, G, Mondelli, M, Muratori, L, Rappuoli, R, Rosa, D, Houghton, M, Abrignani, S, Bonino, F

“…Hepatitis C virus (HCV) vaccines may be able to increase viral clearance in combination with antiviral therapy. We analysed viral dynamics and HCV-specific…”
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O113 : HLA DPB1 rs9277535 polymorphism strongly predicts HBsAg clearance in IFN treated genotype D HBeAg-negative patients with chronic hepatitis B by Lampertico, P, Galmozzi, E, Facchetti, F, Cheroni, C, Invernizzi, F, Valveri, V, Soffredini, R, Viganò, M, Abrignani, S, De Francesco, R, Colombo, M

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The combination of IFN-lambda-4 and HLA-DPB1 polymorphisms accurately predict HBsAg loss in IFN treated genotype D HBeAg-negative patients with chronic hepatitis B by Lampertico, P, Galmozzi, E, Facchetti, F, Cheroni, C, Invernizzi, F, Valveri, V, Soffredini, R, Viganò, M, Abrignani, S, De Francesco, R, Colombo, M

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P.02.11 PHENOTYPIC AND FUNCTIONAL CHARACTERIZATION OF INFLAMMATORY CELL INFILTRATE IN ADULT-ONSET AUTOIMMUNE ENTEROPATHY AND ITS EVOLUTION WITH GLUCOCORTICOIDS by Paroni, M, Magarotto, A, Orlando, S, Nizzoli, G, Gianelli, U, Ciafardini, C, Conte, D, Abrignani, S, Geginat, J, Caprioli, F

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HLA DPB1 rs9277535 polymorphism strongly predicts HBsAg clearance in interferon treated genotype D HBeAg-negative patients with chronic hepatitis B by Lampertico, P, Galmozzi, E, Facchetti, F, Cheroni, C, Invernizzi, F, Valveri, V, Soffredini, R, Viganò, M, Abrignani, S, De Francesco, R, Colombo, M

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Human Monoclonal Antibodies That Inhibit Binding of Hepatitis C Virus E2 Protein to CD81 and Recognize Conserved Conformational Epitopes by Hadlock, K G, Lanford, R E, Perkins, S, Rowe, J, Yang, Q, Levy, S, Pileri, P, Abrignani, S, Foung, S K

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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P.05.9 PHENOTYPIC AND FUNCTIONAL CHARACTERIZATION OF INTRAEPITHELIAL AND LAMINA PROPRIA INFLAMMATORY CELL INFILTRATE IN AUTOIMMUNE ENTEROPATHY by Paroni, M, Nizzoli, G, Magarotto, A, Gianelli, U, Ciafardini, C, Conte, D, Abrignani, S, Geginat, J, Caprioli, F

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A Quantitative Test to Estimate Neutralizing Antibodies to the Hepatitis C Virus: Cytofluorimetric Assessment of Envelope Glycoprotein 2 Binding to Target Cells by Rosa, Domenico, Campagnoli, Susanna, Moretto, Carlo, Guenzi, Eric, Cousens, Lawrence, Chin, Michael, Dong, Christine, Weiner, Amy J., Johnson Y. N. Lau, Choo, Qui-Lim, Chien, David, Pileri, Piero, Houghton, Michael, Abrignani, Sergio

“…Hepatitis C virus (HCV) is a major cause of chronic hepatitis. The virus does not replicate efficiently in cell cultures, and it is therefore difficult to…”
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1318 FIBROSIS PROGRESSION IN PATIENTS WITH CHRONIC HEPATITIS C IS NOT INFLUENCED BY IL28B POLYMORPHISMS by Aghemo, A, Marabita, F, De Nicola, S, Rumi, M.G, Cheroni, C, Scavelli, R, Crimi, M, Soffredini, R, Abrignani, S, De Francesco, R, Colombo, M

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1148 THE PRESENCE OF HEPATITIS C VIRUS DELETION MUTANTS IN CHRONIC HEPATITIS C PATIENTS AND THEIR ROLE DURING PEG-IFN/RIBAVIRIN THERAPY IN HCV-1 PATIENTS by Donnici, L, Cheroni, C, Aghemo, A, Rump, M.G, Valveri, V, Soffredini, R, Prati, G.M, Colombo, M, Abrignani, S, De Francesco, R

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CS15-7. Decrease of IL-17 and Gm-Csf in Intestinal Mucosa of Ibd Patients is Associated With Reduction of CD68+ Macrophages and Clinical Remission in Response to Anti-TNF Therapy by Bose, F., Caprioli, F., Rossi, R., Palazzo, M., Viganò, C., Raeli, L., Moro, M., Basilisco, G., Ferrero, S., Pagani, M., Altomare, G., Abrignani, S., Reali, E.

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OC.06.1 INFLIXIMAB-INDUCED MUCOSAL HEALING ASSOCIATES WITH A DOWN-REGULATION OF IL23/TH17 IN INFLAMMATORY BOWEL DISEASES by Caprioli, F, Bosè, F, Rossi, R, Pagani, M, Basilisco, G, Viganò, C, Ciafardini, C, Ferrero, S, Botti, F, Conte, D, Monteleone, G, Abrignani, S, Reali, E

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P.1.14: INFLIXIMAB MODULATES IL23-TH17 AXIS IN PATIENTS WITH INFLAMMATORY BOWEL DISEASES by Caprioli, F, Bosé, F, Viganò, C, Palazzo, M, Ferrero, S, Basilisco, G, Conte, D, Abrignani, S, Reali, E

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