Search Results - "Abreu, R. A. A."

Molecular Dynamics with Very Large Time Steps for the Calculation of Solvation Free Energies by Abreu, Charlles R. A, Tuckerman, Mark E

“…In multiple time scale molecular dynamics, the use of isokinetic constraints along with massive thermostatting has enabled the adoption of very large…”
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Panic results in unique molecular and network changes in the amygdala that facilitate fear responses by Molosh, A. I., Dustrude, E. T., Lukkes, J. L., Fitz, S. D., Caliman, I. F., Abreu, A. R. R., Dietrich, A. D., Truitt, W. A., Ver Donck, L., Ceusters, M., Kent, J. M., Johnson, P. L., Shekhar, A .

“…Recurrent panic attacks (PAs) are a common feature of panic disorder (PD) and post-traumatic stress disorder (PTSD). Several distinct brain regions are…”
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Blunted GABA-mediated inhibition within the dorsomedial hypothalamus potentiates the cardiovascular response to emotional stress in rats fed a high-fat diet by Abreu, A.R, de Abreu, A.R, Santos, L.T, de Souza, A.A, da Silva, L.G, Chianca, D.A, de Menezes, R.C

“…Highlights • The cardiovascular reactivity to emotional stress is increased in obese rats. • Obesity impairs the reduction in the stress response caused by…”
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Water, sanitation, and hygiene vulnerability in child stunting in developing countries: a systematic review with meta-analysis by Mudadu Silva, J.R., Vieira, L.L., Murta Abreu, A.R., de Souza Fernandes, E., Moreira, T.R., Dias da Costa, G., Mitre Cotta, R.M.

“…This study aimed to perform a systematic review and meta-analysis to assess the scientific evidence of the relationship between vulnerability to access to safe…”
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Amygdalar neuronal activity mediates the cardiovascular responses evoked from the dorsolateral periaqueductal gray in conscious rats by de Abreu, A.R, Abreu, A.R, Santos, L.T, de Souza, A.A, da Silva, L.G, Chianca, D.A, de Menezes, R.C

“…Highlights • Responses elicited by dlPAG activation require the neuronal activity in the BLA. • Responses caused by the dlPAG activation depend on…”
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Uterine haemodynamic, vascularization and blood pressure changes along the oestrous cycle in bitches by Nogueira, IB, Almeida, LL, Angrimani, DSR, Brito, MM, Abreu, RA, Vannucchi, CI

“…Contents Characterization of the bitch's reproductive physiology is of utmost importance for the development of new reproductive techniques and the diagnosis…”
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The influence of benign prostatic hyperplasia on sperm morphological features and sperm DNA integrity in dogs by Flores, RB, Angrimani, DSR, Rui, BR, Brito, MM, Abreu, RA, Vannucchi, CI

“…Contents Benign prostatic hyperplasia (BPH) has a high incidence in older intact dogs. Due to the increased prostatic oxidative stress and hormonal imbalance…”
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Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells by Wielinga, P R, Reid, G, Challa, E E, van der Heijden, I, van Deemter, L, de Haas, M, Mol, C, Kuil, A J, Groeneveld, E, Schuetz, J D, Brouwer, C, De Abreu, R A, Wijnholds, J, Beijnen, J H, Borst, P

“…Mercaptopurines have been used as anticancer agents for more than 40 years, and most acute lymphoblastic leukemias are treated with 6-mercaptopurine (6MP) or…”
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Multiple timescale molecular dynamics with very large time steps: avoidance of resonances by Abreu, C. R. A., Tuckerman, M. E.

“…Reversible multiple timescale (MTS) integration algorithms have long been recognized as a straightforward way to increase efficiency and extend accessible…”
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Thermodynamic Properties of Supercritical Mixtures of Carbon Dioxide and Methane: A Molecular Simulation Study by Aimoli, Cassiano G, Maginn, Edward J, Abreu, Charlles R. A

“…Volumetric and second-derivative thermodynamic properties of binary mixtures of carbon dioxide and methane were calculated under supercritical conditions at…”
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Strategies for surgically assisted rapid maxillary expansion according to the region of transverse maxillary deficiency by Pereira, M.D, de Abreu, R.A.M, Prado, G.P.R, Ferreira, L.M

“…Abstract This study evaluated different techniques for surgically assisted rapid maxillary expansion (SARME) according to the type of transverse maxillary…”
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Methotrexate in rheumatoid arthritis : An update with focus on mechanisms involved in toxicity by VAN EDE, A. E, LAAN, R. F. J. M, BLOM, H. J, DE ABREU, R. A, VAN DE PUTTE, L. B. A

“…To provide an update of the current knowledge of the mechanism of action of low-dose methotrexate (MTX) in the treatment of patients with rheumatoid arthritis…”
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Genetic polymorphism of thiopurine S-methyltransferase in Argentina by Laróvere, L E, de Kremer, R Dodelson, Lambooy, L H J, De Abreu, R A

“…Thiopurine methyltransferase (TPMT) catalyses the S-methylation of 6-thiopurine drugs, which are commonly used in the treatment of autoimmune diseases,…”
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Local and regional albedo observations of arctic first-year sea ice during melt ponding by Hanesiak, J. M., Barber, D. G., De Abreu, R. A., Yackel, J. J.

“…The shortwave surface albedo is a critical climatological parameter for sea ice, especially during the spring melt period when the ice contains a mixture of…”
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Association of high-fat diet with neuroinflammation, anxiety-like defensive behavioral responses, and altered thermoregulatory responses in male rats by Noronha, S.S.R., Lima, P.M., Campos, G.S.V., Chírico, M.T.T., Abreu, A.R., Figueiredo, A.B., Silva, F.C.S., Chianca, D.A., Lowry, C.A., De Menezes, R.C.A.

“…[Display omitted] •High-fat diet (HFD) induced obesity and provoked neuroinflammatory responses.•HFD increased anxiety-related defensive behavioral…”
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Genotype and phenotype in patients with dihydropyrimidine dehydrogenase deficiency by VAN KUILENBURG, A. B. P, VREKEN, P, CHRISTENSEN, E, HOLOPAINEN, I, PULKKI, K, RIVA, D, BOTTEON, G, HOLME, E, TULINIUS, M, KLEIJER, W. J, BEEMER, F. A, DURAN, M, ABELING, N. G. G. M, NIEZEN-KONING, K. E, SMIT, G. P. A, JAKOBS, C, SMIT, L. M. E, MOOG, U, SPAAPEN, L. J. M, VAN GENNIP, A. H, BAKKER, H. D, MEINSMA, R, VAN LENTHE, H, DE ABREU, R. A, SMEITINK, J. A. M, KAYSERILI, H, APAK, M. Y

“…Dihydropyrimidine dehydrogenase (DPD) deficiency is an autosomal recessive disease characterised by thymine-uraciluria in homozygous deficient patients and has…”
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Abdominal TRPV1 channel desensitization enhances stress-induced hyperthermia during social stress in rats by Reis, T.O., Noronha, S.I.S.R., Lima, P.M.A., De Abreu, A.R.R., Mesquita, L.B.T., Ferreira, F.I., Silva, F.C., Chianca-Jr, D.A., De Menezes, R.C.

“…In rats, stress-induced hyperthermia caused by social interaction depends on brown adipose tissue (BAT) thermogenesis and peripheral vasoconstriction. However,…”
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Heterozygosity for a point mutation in an invariant splice donor site of dihydropyrimidine dehydrogenase and severe 5-fluorouracil related toxicity by Van Kuilenburg, A.B.P., Vreken, P., Beex, L.V.A.M., Meinsma, R., Van Lenthe, H., De Abreu, R.A., Van Gennip, A.H.

“…Dihydropyrimidine dehydrogenase (DPD) is responsible for the breakdown of the widely used antineoplastic agent 5-fluorouracil (5-FU), thereby limiting the…”
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Effects of benign prostatic hyperplasia and finasteride therapy on prostatic blood flow in dogs by Angrimani, D.S.R., Silvestrini, G.R., Brito, M.M., Abreu, R.A., Almeida, L.L., Vannucchi, C.I.

“…Benign prostatic hyperplasia (BPH) is characterized by an enlargement of the prostate accompanied by an increase in prostatic blood perfusion and…”
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Purine enzymes in patients with rheumatoid arthritis treated with methotrexate by van Ede, A E, Laan, R F J M, De Abreu, R A, Stegeman, A B J, van de Putte, L B A

“…Objectives: To study (a) purine metabolism during treatment with methotrexate (MTX) in patients with rheumatoid arthritis (RA) and (b) the relation of purine…”
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