Search Results - "Abreu, Maria"

Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function by Abreu, Maria T

“…Key Points A single layer of intestinal epithelial cells (IECs) provides a physical barrier that separates trillions of commensal bacteria in the intestinal…”
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The nature of academic entrepreneurship in the UK: Widening the focus on entrepreneurial activities by Abreu, Maria, Grinevich, Vadim

“…► We argue that the concept of academic entrepreneurship should be widened. ► We present a new, wider, definition of academic entrepreneurship. ► Determinants…”
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JAK1 Inhibition to Treat Crohn’s Disease by Abreu, Maria T.

“…This editorial describes the science behind clinical trials that tested upadacitinib, a drug that targets JAK1, for efficacy in treating Crohn’s disease…”
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Epithelial Toll-like receptors and their role in gut homeostasis and disease by Burgueño, Juan F., Abreu, Maria T.

“…The human gastrointestinal tract is colonized by trillions of microorganisms that interact with the host to maintain structural and functional homeostasis…”
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STRIDE-II: An Update on the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) Initiative of the International Organization for the Study of IBD (IOIBD): Determining Therapeutic Goals for Treat-to-Target strategies in IBD by Turner, Dan, Ricciuto, Amanda, Lewis, Ayanna, D’Amico, Ferdinando, Dhaliwal, Jasbir, Griffiths, Anne M., Bettenworth, Dominik, Sandborn, William J., Sands, Bruce E., Reinisch, Walter, Schölmerich, Jürgen, Bemelman, Willem, Danese, Silvio, Mary, Jean Yves, Rubin, David, Colombel, Jean-Frederic, Peyrin-Biroulet, Laurent, Dotan, Iris, Abreu, Maria T., Dignass, Axel

“…The Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) initiative of the International Organization for the Study of Inflammatory Bowel…”
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Ustekinumab as Induction and Maintenance Therapy for Ulcerative Colitis by Sands, Bruce E, Sandborn, William J, Panaccione, Remo, O’Brien, Christopher D, Zhang, Hongyan, Johanns, Jewel, Adedokun, Omoniyi J, Li, Katherine, Peyrin-Biroulet, Laurent, Van Assche, Gert, Danese, Silvio, Targan, Stephan, Abreu, Maria T, Hisamatsu, Tadakazu, Szapary, Philippe, Marano, Colleen

“…Patients with moderate-to-severe ulcerative colitis were randomly assigned to receive placebo or induction doses of ustekinumab. Patients who had a response to…”
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Pattern Recognition Receptor Signaling and Cytokine Networks in Microbial Defenses and Regulation of Intestinal Barriers: Implications for Inflammatory Bowel Disease by Abraham, Clara, Abreu, Maria T., Turner, Jerrold R.

“…Inflammatory bowel disease is characterized by defects in epithelial function and dysregulated inflammatory signaling by lamina propria mononuclear cells…”
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Gastrointestinal Malignancy and the Microbiome by Abreu, Maria T, Peek, Richard M

“…Microbial species participate in the genesis of a substantial number of malignancies—in conservative estimates, at least 15% of all cancer cases are…”
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Morphine tolerance is attenuated in germfree mice and reversed by probiotics, implicating the role of gut microbiome by Zhang, Li, Meng, Jingjing, Ban, Yuguang, Jalodia, Richa, Chupikova, Irina, Fernandez, Irina, Brito, Nivis, Sharma, Umakant, Abreu, Maria T., Ramakrishnan, Sundaram, Roy, Sabita

“…Prolonged exposure to opioids results in analgesic tolerance, drug overdose, and death. The mechanism underlying morphine analgesic tolerance still remains…”
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Exercise attenuates PCB-induced changes in the mouse gut microbiome by Choi, Jeong June, Eum, Sung Yong, Rampersaud, Evadnie, Daunert, Sylvia, Abreu, Maria T, Toborek, Michal

“…The gut microbiome, a dynamic bacterial community that interacts with the host, is integral to human health because it regulates energy metabolism and immune…”
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A Comprehensive Literature Review and Expert Consensus Statement on Therapeutic Drug Monitoring of Biologics in Inflammatory Bowel Disease by Cheifetz, Adam S., Abreu, Maria T., Afif, Waqqas, Cross, Raymond K., Dubinsky, Marla C., Loftus, Edward V., Osterman, Mark T., Saroufim, Ariana, Siegel, Corey A., Yarur, Andres J., Melmed, Gil Y., Papamichael, Konstantinos

“…Therapeutic drug monitoring (TDM) of biologics is a rapidly evolving field. We aimed to provide a consensus statement regarding the clinical utility of TDM for…”
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Correction to: How Did It Get So Difficult to Care for Patients With Inflammatory Bowel Disease? by Abreu, Maria T, Kosinski, Lawrence R

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How Did It Get So Difficult to Care for Patients With Inflammatory Bowel Disease? by Abreu, Maria T, Kosinski, Lawrence R

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DDS Perspective: My Take on Therapeutic Drug Monitoring in IBD by Abreu, Maria T.

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Efficacy and Safety of Maintenance Ustekinumab for Ulcerative Colitis Through 3 Years: UNIFI Long-term Extension by Abreu, Maria T, Rowbotham, David S, Danese, Silvio, Sandborn, William J, Miao, Ye, Zhang, Hongyan, Tikhonov, Ilia, Panaccione, Remo, Hisamatsu, Tadakazu, Scherl, Ellen J, Leong, Rupert W, Arasaradnam, Ramesh P, Afif, Waqqas, Peyrin-Biroulet, Laurent, Sands, Bruce E, Marano, Colleen

“…Abstract Background and Aims The UNIFI long-term extension [LTE] study reports the efficacy and safety of subcutaneous 90 mg ustekinumab through 3 years of…”
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DDS Profile: Maria T. Abreu, MD by Abreu, Maria T.

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Pro-inflammatory human Th17 cells selectively express P-glycoprotein and are refractory to glucocorticoids by Ramesh, Radha, Kozhaya, Lina, McKevitt, Kelly, Djuretic, Ivana M, Carlson, Thaddeus J, Quintero, Maria A, McCauley, Jacob L, Abreu, Maria T, Unutmaz, Derya, Sundrud, Mark S

“…IL-17A-expressing CD4(+) T cells (Th17 cells) are generally regarded as key effectors of autoimmune inflammation. However, not all Th17 cells are…”
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Lean management and sustainable practices in Higher Education Institutions of Brazil and Portugal: A cross country perspective by Klein, Leander Luiz, Alves, Anabela Carvalho, Abreu, Maria Florentina, Feltrin, Thiago Schirmer

“…The objective of this paper is to evaluate the perception of Lean management practices and its influence on sustainability practices in Higher Education…”
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High-Resolution Lipidomics of the Early Life Stages of the Red Seaweed Porphyra dioica by da Costa, Elisabete, Azevedo, Vitor, Melo, Tânia, Rego, Andreia M, V Evtuguin, Dmitry, Domingues, Pedro, Calado, Ricardo, Pereira, Rui, Abreu, Maria H, Domingues, Maria R

“…is a commercial seaweed consumed all over the world, mostly in the shape of nori sheets used for "sushi" preparation. It is a well-known part of the Asian diet…”
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Exposing the Achilles Heel of Antibiotic Therapy for Pouchitis Using Microbial Function and Composition by Fritsch, Julia, Abreu, Maria T.

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