Search Results - "Abrescia, Nicola G A"

Seroprevalence of adeno-associated virus types 1, 2, 3, 4, 5, 6, 8, and 9 in a Basque cohort of healthy donors by Navarro-Oliveros, Miguel, Vidaurrazaga, Ander, Soares Guerra, Gabriel, Castellana, Donatello, Embade, Nieves, Millet, Oscar, Marigorta, Urko M., Abrescia, Nicola G. A.

“…Adeno-associated viruses (AAVs) are promising gene therapy vectors, but challenges arise when treating patients with preexisting neutralizing antibodies…”
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Structural basis for assembly of vertical single β-barrel viruses by Santos-Pérez, Isaac, Charro, Diego, Gil-Carton, David, Azkargorta, Mikel, Elortza, Felix, Bamford, Dennis H., Oksanen, Hanna M., Abrescia, Nicola G. A.

“…The vertical double β-barrel major capsid protein (MCP) fold, fingerprint of the PRD1-adeno viral lineage, is widespread in many viruses infecting organisms…”
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A novel Schmallenberg virus subunit vaccine candidate protects IFNAR-/- mice against virulent SBV challenge by Boshra, Hani, Lorenzo, Gema, Charro, Diego, Moreno, Sandra, Guerra, Gabriel Soares, Sanchez, Isbene, Garrido, Joseba M., Geijo, Marivi, Brun, Alejandro, Abrescia, Nicola G. A.

“…Schmallenberg virus (SBV), an arthropod-transmitted pathogenic bunyavirus, continues to be a threat to the European livestock industry, causing morbidity and…”
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Evolution of complex RNA polymerases: the complete archaeal RNA polymerase structure by Korkhin, Yakov, Unligil, Ulug M, Littlefield, Otis, Nelson, Pamlea J, Stuart, David I, Sigler, Paul B, Bell, Stephen D, Abrescia, Nicola G A

“…The archaeal RNA polymerase (RNAP) shares structural similarities with eukaryotic RNAP II but requires a reduced subset of general transcription factors for…”
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Capsid-deficient alphaviruses generate propagative infectious microvesicles at the plasma membrane by Ruiz-Guillen, Marta, Gabev, Evgeni, Quetglas, Jose I., Casales, Erkuden, Ballesteros-Briones, María Cristina, Poutou, Joanna, Aranda, Alejandro, Martisova, Eva, Bezunartea, Jaione, Ondiviela, Marina, Prieto, Jesus, Hernandez-Alcoceba, Ruben, Abrescia, Nicola G. A., Smerdou, Cristian

“…Alphavirus budding is driven by interactions between nucleocapsids assembled in the cytoplasm and envelope proteins present at the plasma membrane. So far, the…”
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Functional and structural studies of the vaccinia virus virulence factor N1 reveal a Bcl-2-like anti-apoptotic protein by Cooray, Samantha, Bahar, Mohammad W, Abrescia, Nicola G. A, McVey, Colin E, Bartlett, Nathan W, Chen, Ron A.-J, Stuart, David I, Grimes, Jonathan M, Smith, Geoffrey L

“…1 Department of Virology, Faculty of Medicine, Imperial College London, St Mary's Campus, Norfolk Place, London W2 1PG, UK 2 The Oxford Protein Production…”
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Specificity of the VP1 GH Loop of Foot-and-Mouth Disease Virus for αv Integrins by BURMAN, Alison, CLARK, Stuart, ABRESCIA, Nicola G. A, FRY, Elizabeth E, STUART, David I, JACKSON, Terry

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Insights into assembly from structural analysis of bacteriophage PRD1 by Stuart, David I, Bamford, Jaana K. H, Abrescia, Nicola G. A, Cockburn, Joseph J. B, Grimes, Jonathan M, Sutton, Geoffrey C, Diprose, Jonathan M, Butcher, Sarah J, Fuller, Stephen D, San Martín, Carmen, Burnett, Roger M, Bamford, Dennis H

“…The structure of the membrane-containing bacteriophage PRD1 has been determined by X-ray crystallography at about 4 A resolution. Here we describe the…”
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Structure and function of A41, a vaccinia virus chemokine binding protein by Bahar, Mohammad W, Kenyon, Julia C, Putz, Mike M, Abrescia, Nicola G A, Pease, James E, Wise, Emma L, Stuart, David I, Smith, Geoffrey L, Grimes, Jonathan M

“…The vaccinia virus (VACV) A41L gene encodes a secreted 30 kDa glycoprotein that is nonessential for virus replication but affects the host response to…”
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Rules of engagement between αvβ6 integrin and foot-and-mouth disease virus by Kotecha, Abhay, Wang, Quan, Dong, Xianchi, Ilca, Serban L., Ondiviela, Marina, Zihe, Rao, Seago, Julian, Charleston, Bryan, Fry, Elizabeth E., Abrescia, Nicola G. A., Springer, Timothy A., Huiskonen, Juha T., Stuart, David I.

“…Foot-and-mouth disease virus (FMDV) mediates cell entry by attachment to an integrin receptor, generally αvβ6, via a conserved arginine–glycine–aspartic acid…”
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New Glucosamine-Based TLR4 Agonists: Design, Synthesis, Mechanism of Action, and In Vivo Activity as Vaccine Adjuvants by Romerio, Alessio, Gotri, Nicole, Franco, Ana Rita, Artusa, Valentina, Shaik, Mohammed Monsoor, Pasco, Samuel T., Atxabal, Unai, Matamoros-Recio, Alejandra, Mínguez-Toral, Marina, Zalamea, Juan Diego, Franconetti, Antonio, Abrescia, Nicola G. A., Jimenez-Barbero, Jesus, Anguita, Juan, Martín-Santamaría, Sonsoles, Peri, Francesco

“…We disclose here a panel of small-molecule TLR4 agonists (the FP20 series) whose structure is derived from previously developed TLR4 ligands (FP18 series). The…”
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Structure Unifies the Viral Universe by Abrescia, Nicola G.A, Bamford, Dennis H, Grimes, Jonathan M, Stuart, David I

“…Is it possible to meaningfully comprehend the diversity of the viral world? We propose that it is. This is based on the observation that, although there is…”
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Immunization with a small fragment of the Schmallenberg virus nucleoprotein highly conserved across the Orthobunyaviruses of the Simbu serogroup reduces viremia in SBV challenged IFNAR-/- mice by Guerra, Gabriel Soares, Barriales, Diego, Lorenzo, Gema, Moreno, Sandra, Anguita, Juan, Brun, Alejandro, Abrescia, Nicola G.A.

“…•A short fragment of the nucleoprotein of Schmallenberg virus has been identified as candidate subunit vaccine.•The candidate subunit vaccine reduces viraemia…”
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The postfusion structure of baculovirus gp64 supports a unified view of viral fusion machines by Stuart, David I, Jones, Ian M, Abrescia, Nicola G A, Loureiro, Silvia, Kadlec, Jan

“…Viral fusion proteins are required for the fusion of viral and host membranes for all enveloped viruses. The structure of the Baculovirus postfusion form of…”
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Cellular and Structural Characterization of VP1 and VP2 Knockout Mutants of AAV3B Serotype and Implications for AAV Manufacturing by Arriaga, Iker, Navarro, Aitor, Etxabe, Amaia, Trigueros, César, Samulski, R Jude, Moullier, Philippe, François, Achille, Abrescia, Nicola G A

“…AAV virion biology is still lacking a complete understanding of the role that the various structural subunits (VP1, 2, and 3) play in virus assembly,…”
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Membrane structure and interactions with protein and DNA in bacteriophage PRD1 by Bamford, Dennis H, Stuart, David I, Cockburn, Joseph J. B, Abrescia, Nicola G. A, Grimes, Jonathan M, Sutton, Geoffrey C, Diprose, Jonathan M, Benevides, James M, Thomas, George J, Bamford, Jaana K. H

“…Membranes are essential for selectively controlling the passage of molecules in and out of cells and mediating the response of cells to their environment…”
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Bacteriophage PRD1 as a nanoscaffold for drug loading by Duyvesteyn, Helen M E, Santos-Pérez, Isaac, Peccati, Francesca, Martinez-Castillo, Ane, Walter, Thomas S, Reguera, David, Goñi, Felix M, Jiménez-Osés, Gonzalo, Oksanen, Hanna M, Stuart, David I, Abrescia, Nicola G A

“…Viruses are very attractive biomaterials owing to their capability as nanocarriers of genetic material. Efforts have been made to functionalize self-assembling…”
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Mechanism of membranous tunnelling nanotube formation in viral genome delivery by Peralta, Bibiana, Gil-Carton, David, Castaño-Díez, Daniel, Bertin, Aurelie, Boulogne, Claire, Oksanen, Hanna M, Bamford, Dennis H, Abrescia, Nicola G A

“…In internal membrane-containing viruses, a lipid vesicle enclosed by the icosahedral capsid protects the genome. It has been postulated that this internal…”
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Cross-Linking Effects Dictate the Preference of Galectins to Bind LacNAc-Decorated HPMA Copolymers by Bertuzzi, Sara, Gimeno, Ana, Martinez-Castillo, Ane, Lete, Marta G., Delgado, Sandra, Airoldi, Cristina, Rodrigues Tavares, Marina, Bláhová, Markéta, Chytil, Petr, Křen, Vladimír, Abrescia, Nicola G. A., Ardá, Ana, Bojarová, Pavla, Jiménez-Barbero, Jesús

“…The interaction of multi-LacNAc (Galβ1-4GlcNAc)-containing N-(2-hydroxypropyl) methacrylamide (HPMA) copolymers with human galectin-1 (Gal-1) and the…”
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Assessing the Mobility of Severe Acute Respiratory Syndrome Coronavirus-2 Spike Protein Glycans by Structural and Computational Methods by Stagnoli, Soledad, Peccati, Francesca, Connell, Sean R, Martinez-Castillo, Ane, Charro, Diego, Millet, Oscar, Bruzzone, Chiara, Palazon, Asis, Ardá, Ana, Jiménez-Barbero, Jesús, Ereño-Orbea, June, Abrescia, Nicola G A, Jiménez-Osés, Gonzalo

“…Two years after its emergence, the coronavirus disease-2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) remains…”
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