Search Results - "Abramsson, Alexandra"

Endothelial/Pericyte Interactions by Armulik, Annika, Abramsson, Alexandra, Betsholtz, Christer

“…Interactions between endothelial cells and mural cells (pericytes and vascular smooth muscle cells) in the blood vessel wall have recently come into focus as…”
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The localization of amyloid precursor protein to ependymal cilia in vertebrates and its role in ciliogenesis and brain development in zebrafish by Chebli, Jasmine, Rahmati, Maryam, Lashley, Tammaryn, Edeman, Brigitta, Oldfors, Anders, Zetterberg, Henrik, Abramsson, Alexandra

“…Amyloid precursor protein (APP) is expressed in many tissues in human, mice and in zebrafish. In zebrafish, there are two orthologues, Appa and Appb…”
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Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors by Abramsson, Alexandra, Lindblom, Per, Betsholtz, Christer

“…Tumor-infiltrating blood vessels deviate morphologically and biochemically from normal vessels, raising the prospect of selective pharmacological targeting…”
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Amyloid precursor protein-b facilitates cell adhesion during early development in zebrafish by Banote, Rakesh Kumar, Chebli, Jasmine, Şatır, Tuğçe Munise, Varshney, Gaurav K., Camacho, Rafael, Ledin, Johan, Burgess, Shawn M., Abramsson, Alexandra, Zetterberg, Henrik

“…Understanding the biological function of amyloid beta (Aβ) precursor protein (APP) beyond its role in Alzheimer’s disease is emerging. Yet, its function during…”
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VEGF Guides Angiogenic Sprouting Utilizing Endothelial Tip Cell Filopodia by Gerhardt, Holger, Golding, Matthew, Fruttiger, Marcus, Ruhrberg, Christiana, Lundkvist, Andrea, Abramsson, Alexandra, Jeltsch, Michael, Mitchell, Christopher, Alitalo, Kari, Shima, David, Betsholtz, Christer

“…Vascular endothelial growth factor (VEGF-A) is a major regulator of blood vessel formation and function. It controls several processes in endothelial cells,…”
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Neuropilin‐1 is required for endothelial tip cell guidance in the developing central nervous system by Gerhardt, Holger, Ruhrberg, Christiana, Abramsson, Alexandra, Fujisawa, Hajime, Shima, David, Betsholtz, Christer

“…Recent evidence indicates that sprouting angiogenesis in the central nervous system (CNS) is a guided process similar to the guidance of axons and insect…”
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Repurposing proteasome inhibitors for improved treatment of triple-negative breast cancer by Larsson, Peter, Pettersson, Daniella, Olsson, Maxim, Sarathchandra, Sithumini, Abramsson, Alexandra, Zetterberg, Henrik, Ittner, Ella, Forssell-Aronsson, Eva, Kovács, Anikó, Karlsson, Per, Helou, Khalil, Parris, Toshima Z.

“…Triple-negative breast cancer (TNBC) is associated with poor prognosis and limited treatment options due to the lack of important receptors (estrogen receptor…”
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Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wall by Lindblom, Per, Gerhardt, Holger, Liebner, Stefan, Abramsson, Alexandra, Enge, Maria, Hellstrom, Mats, Backstrom, Gudrun, Fredriksson, Simon, Landegren, Ulf, Nystrom, Henrik C, Bergstrom, Goran, Dejana, Elisabetta, Ostman, Arne, Lindahl, Per, Betsholtz, Christer

“…Several platelet-derived growth factor (PDGF) and vascular endothelial growth factor (VEGF) family members display C-terminal protein motifs that confer…”
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Endothelium-specific ablation of PDGFB leads to pericyte loss and glomerular, cardiac and placental abnormalities by Bjarnegård, Mattias, Enge, Maria, Norlin, Jenny, Gustafsdottir, Sigrun, Fredriksson, Simon, Abramsson, Alexandra, Takemoto, Minoru, Gustafsson, Erika, Fässler, Reinhard, Betsholtz, Christer

“…Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development, but the relative importance of different cellular sources of PDGFB…”
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SILAC zebrafish for quantitative analysis of protein turnover and tissue regeneration by Westman-Brinkmalm, Ann, Abramsson, Alexandra, Pannee, Josef, Gang, Chen, Gustavsson, Mikael K., von Otter, Malin, Blennow, Kaj, Brinkmalm, Gunnar, Heumann, Hermann, Zetterberg, Henrik

“…Defective tissue regeneration is thought to contribute to several human diseases, including neurodegenerative disorders, heart failure and various lung…”
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Modulation of dorsal root ganglion development by ErbB signaling and the scaffold protein Sorbs3 by Malmquist, Sarah J, Abramsson, Alexandra, McGraw, Hillary F, Linbo, Tor H, Raible, David W

“…The multipotent cells of the vertebrate neural crest (NC) arise at the dorsal aspect of the neural tube, then migrate throughout the developing embryo and…”
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Transcription Profiling of Platelet-Derived Growth Factor-B-Deficient Mouse Embryos Identifies RGS5 as a Novel Marker for Pericytes and Vascular Smooth Muscle Cells by Bondjers, Cecilia, Kalén, Mattias, Hellström, Mats, Scheidl, Stefan J., Abramsson, Alexandra, Renner, Oliver, Lindahl, Per, Cho, Hyeseon, Kehrl, John, Betsholtz, Christer

“…All blood capillaries consist of endothelial tubes surrounded by mural cells referred to as pericytes. The origin, recruitment, and function of the pericytes…”
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Platelet-derived growth factor production by B16 melanoma cells leads to increased pericyte abundance in tumors and an associated increase in tumor growth rate by FURUHASHI, Masao, SJÖBLOM, Tohias, HELDIN, Carl-Henrik, ÖSTMAN, Arne, ABRAMSSON, Alexandra, ELLINGSEN, Jens, MICKE, Patrick, HONG LI, BERGSTEN-FOLESTAD, Erika, ERIKSSON, Ulf, HEUCHEL, Rainer, BETSHOLTZ, Christer

“…Platelet-derived growth factor (PDGF) receptor signaling participates in different processes in solid tumors, including autocrine stimulation of tumor cell…”
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Analysis of mural cell recruitment to tumor vessels by ABRAMSSON, Alexandra, BERLIN, Örjan, PAPAYAN, Hayk, PAULIN, Denise, SHANI, Moshe, BETSHOLTZ, Christer

“…Tumor blood vessels are both structurally and functionally abnormal compared with normal vessels. A limited support of mural cells may contribute to these…”
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Defective oligodendrocyte development and severe hypomyelination in PDGF-A knockout mice by Fruttiger, M, Karlsson, L, Hall, A C, Abramsson, A, Calver, A R, Boström, H, Willetts, K, Bertold, C H, Heath, J K, Betsholtz, C, Richardson, W D

“…There is a class of oligodendrocyte progenitors, called O-2A progenitors, that is characterized by expression of platelet-derived growth factor α-receptors…”
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The zebrafish brain proteome project by Abramsson, Alexandra V, Brinkmalm, Ann, Andersson, Malin E, Gang, Chen, Brinkmalm, Gunnar, Gustavsson, Mikael, Pannee, Josef, Heumann, Hermann, Zetterberg, Henrik

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P2‐220: CROSS‐TALK BETWEEN WNT SIGNALLING AND AMYLOID PRECURSOR PROTEIN IN NEURONS by Ehyai, Saviz, Abramsson, Alexandra, Zetterberg, Henrik

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CROSS-TALK BETWEEN WNT SIGNALLING AND AMYLOID PRECURSOR PROTEIN IN NEURONS by Ehyai, Saviz, Abramsson, Alexandra, Zetterberg, Henrik

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Fine-tuning amyloid precursor protein expression through non-sense mediated mRNA decay by Rahmati, Maryam, Chebli, Jasmine, Banote, Rakesh Kumar, Roselli, Sandra, Agholme, Lotta, Zetterberg, Henrik, Abramsson, Alexandra

“…Studies on genetic robustness recently revealed transcriptional adaptation (TA) as a mechanism by which an organism can compensate for genetic mutations…”
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Cell stemness is maintained upon concurrent expression of RB and the mitochondrial ribosomal protein S18-2 by Mushtaq, Muhammad, Darekar, Suhas, Abramsson, Alexandra, Zetterberg, Henrik, Kashuba, Vladimir, Klein, George, Arsenian-Henriksson, Marie, Kashuba, Elena

“…Stemness encompasses the capability of a cell for self-renewal and differentiation. The stem cell maintains a balance between proliferation, quiescence, and…”
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