Search Results - "Abramson, RG"
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Abstract P4-01-03: quantitative DCE-MRI to predict the response of primary breast cancer to neoadjuvant therapy
Published in Cancer research (Chicago, Ill.) (15-12-2012)“…Abstract The goal of this study was to determine if quantitative changes in dynamic contrast enhanced MRI (DCE-MRI) following a single cycle of chemotherapy…”
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Uric acid transport
Published in Current opinion in nephrology and hypertension (01-09-2003)“…PURPOSE OF REVIEWThe goal of this article is to review the physiology and describe newly defined molecular mechanisms that are responsible for renal urate…”
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Functional reconstitution, membrane targeting, genomic structure, and chromosomal localization of a human urate transporter
Published in The Journal of clinical investigation (01-05-2001)“…Elevated serum levels of uric acid have been associated with an increased risk for gout, hypertension, cardiovascular disease, and renal failure. The molecular…”
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Current and emerging quantitative magnetic resonance imaging methods for assessing and predicting the response of breast cancer to neoadjuvant therapy
Published in Breast cancer targets and therapy (01-01-2012)“…Reliable early assessment of breast cancer response to neoadjuvant therapy (NAT) would provide considerable benefit to patient care and ongoing research…”
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Galectin 9 is the sugar-regulated urate transporter/channel UAT
Published in Glycoconjugate journal (2002)“…UAT, also designated galectin 9, is a multifunctional protein that can function as a urate channel/transporter, a regulator of thymocyte-epithelial cell…”
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Functional analysis and molecular model of the human urate transporter/channel, hUAT
Published in American journal of physiology. Renal physiology (01-07-2002)“…Recombinant protein, designated hUAT, the human homologue of the rat urate transporter/channel (UAT), functions as a highly selective urate channel in lipid…”
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Localization and topology of a urate transporter/channel, a galectin, in epithelium-derived cells
Published in American Journal of Physiology: Cell Physiology (01-12-2001)“…Recombinant protein produced from a cDNA cloned in our laboratory (UAT) functions in lipid bilayers as a urate transporter/channel. Because UAT is a galectin,…”
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Molecular Cloning and Functional Reconstitution of a Urate Transporter/Channel
Published in The Journal of biological chemistry (03-01-1997)“…Maintenance of urate homeostasis requires urate efflux from urate-producing cells with subsequent renal and gastrointestinal excretion. The molecular basis for…”
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Expression of the urate transporter/channel is developmentally regulated in human kidneys
Published in American journal of physiology. Renal physiology (01-11-2001)“…Recombinant protein prepared from cDNA cloned from rat kidney and its human homolog function as urate transporter/channels in lipid bilayers. Using the…”
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Cost-effectiveness of hepatic arterial chemoembolization for colorectal liver metastases refractory to systemic chemotherapy
Published in Radiology (01-08-2000)“…To calculate the cost-effectiveness of hepatic arterial chemoembolization (HACE) for the treatment of colorectal liver metastases (CLM) over a range of…”
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Functional analysis and molecular modeling of a cloned urate transporter/channel
Published in The Journal of membrane biology (01-05-1999)“…Recombinant protein, designated UAT, prepared from a cloned rat renal cDNA library functions as a selective voltage-sensitive urate transporter/channel when…”
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Ontogeny of Na/H antiporter activity in rabbit renal brush border membrane vesicles
Published in The Journal of clinical investigation (01-06-1991)“…The development of the Na/H antiporter was studied in renal brush border membrane vesicles (BBMV) from fetal and adult rabbits using isotopic and fluorescent…”
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Classical and channel-like urate transporters in rabbit renal brush border membranes
Published in Kidney international (01-03-1994)“…Classical and channel-like urate transporters in rabbit renal brush border membranes. The precise mechanism by which urate is transported across rabbit renal…”
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Isolation and immunolocalization of a rat renal cortical membrane urate transporter
Published in The Journal of biological chemistry (04-03-1994)“…Two modalities of urate transport have been reported in rat kidney, a urate/anion exchanger and a potential sensitive, uricase-like uniporter. As an initial…”
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Reconstitution of hepatic uricase in planar lipid bilayer reveals a functional organic anion channel
Published in The Journal of membrane biology (01-07-1995)“…Rat renal proximal tubule cell membranes have been reported to contain uricase-like proteins that function as electrogenic urate transporters. Although…”
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Characterization of the fetal glucose transporter in rabbit kidney: comparison with the adult brush border electrogenic Na+-glucose symporter
Published in The Journal of clinical investigation (01-08-1988)“…Glucose transport was characterized in rabbit renal brush border membrane vesicles (BBMV) of the fetus late in gestation. Highly purified, osmotically reactive…”
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State involvement in medical technology assessment
Published in Health Affairs (1995)“…State governments are reevaluating their role in the assessment of medical technologies. This paper outlines a range of state technology assessment activities,…”
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Modulation of the ionic permeability of renal cortical brush-border membranes by cAMP
Published in The American journal of physiology (01-11-1989)“…The effects of adenosine 3',5'-cyclic monophosphate (cAMP) on potassium chloride permeability, relative ionic permeabilities, and Na+-dependent glucose…”
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Differential permeabilities of rat renal brush-border and basolateral membrane vesicles
Published in The American journal of physiology (01-01-1989)“…Potassium chloride permeability and relative ionic conductances of rat renal cortical brush-border (BBMV) and basolateral (BLMV) membrane vesicles were…”
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Hormonal regulation of rat renal proximal tubule brush-border membrane ionic permeability
Published in The American journal of physiology (01-07-1992)“…The effects on ionic permeability of toxins and hormones that activate or deactivate the guanine nucleotide regulatory (G) proteins that govern adenylate…”
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