Search Results - "Abramson, R G"

Expression of the urate transporter/channel is developmentally regulated in human kidneys by Hyink, D P, Rappoport, J Z, Wilson, P D, Abramson, R G

“…Recombinant protein prepared from cDNA cloned from rat kidney and its human homolog function as urate transporter/channels in lipid bilayers. Using the…”
Get more information

Cost-effectiveness of hepatic arterial chemoembolization for colorectal liver metastases refractory to systemic chemotherapy by Abramson, R G, Rosen, M P, Perry, L J, Brophy, D P, Raeburn, S L, Stuart, K E

“…To calculate the cost-effectiveness of hepatic arterial chemoembolization (HACE) for the treatment of colorectal liver metastases (CLM) over a range of…”
Get more information

Functional analysis and molecular modeling of a cloned urate transporter/channel by Leal-Pinto, E, Cohen, B E, Abramson, R G

“…Recombinant protein, designated UAT, prepared from a cloned rat renal cDNA library functions as a selective voltage-sensitive urate transporter/channel when…”
Get full text

Isolation and immunolocalization of a rat renal cortical membrane urate transporter by KNORR, B. A, LIPKOWITZ, M. S, POTTER, B. J, MASUR, S. K, ABRAMSON, R. G

“…Two modalities of urate transport have been reported in rat kidney, a urate/anion exchanger and a potential sensitive, uricase-like uniporter. As an initial…”
Get full text

Ontogeny of Na/H antiporter activity in rabbit renal brush border membrane vesicles by BECK, J. C, LIPKOWITZ, M. S, ABRAMSON, R. G

“…The development of the Na/H antiporter was studied in renal brush border membrane vesicles (BBMV) from fetal and adult rabbits using isotopic and fluorescent…”
Get full text

Characterization of the fetal glucose transporter in rabbit kidney: comparison with the adult brush border electrogenic Na+-glucose symporter by BECK, J. C, LIPKOWITZ, M. S, ABRAMSON, R. G

“…Glucose transport was characterized in rabbit renal brush border membrane vesicles (BBMV) of the fetus late in gestation. Highly purified, osmotically reactive…”
Get full text

Functional reconstitution, membrane targeting, genomic structure, and chromosomal localization of a human urate transporter by Lipkowitz, M S, Leal-Pinto, E, Rappoport, J Z, Najfeld, V, Abramson, R G

“…Elevated serum levels of uric acid have been associated with an increased risk for gout, hypertension, cardiovascular disease, and renal failure. The molecular…”
Get full text

Modulation of the ionic permeability of renal cortical brush-border membranes by cAMP by Lipkowitz, M S, Abramson, R G

“…The effects of adenosine 3',5'-cyclic monophosphate (cAMP) on potassium chloride permeability, relative ionic permeabilities, and Na+-dependent glucose…”
Get full text

Differential permeabilities of rat renal brush-border and basolateral membrane vesicles by Lipkowitz, M S, Abramson, R G

“…Potassium chloride permeability and relative ionic conductances of rat renal cortical brush-border (BBMV) and basolateral (BLMV) membrane vesicles were…”
Get full text

Hormonal regulation of rat renal proximal tubule brush-border membrane ionic permeability by Lipkowitz, M S, London, R D, Beck, J C, Abramson, R G

“…The effects on ionic permeability of toxins and hormones that activate or deactivate the guanine nucleotide regulatory (G) proteins that govern adenylate…”
Get full text

Classical and channel-like urate transporters in rabbit renal brush border membranes by Knorr, Barbara A., Beck, Jeanne C., Abramson, Ruth G.

“…Classical and channel-like urate transporters in rabbit renal brush border membranes. The precise mechanism by which urate is transported across rabbit renal…”
Get full text

Altered membrane ionic permeability in a rat model of chronic renal failure by London, Roger D., Lipkowitz, Michael S., Abramson, Ruth G.

“…Altered membrane ionic permeability in a rat model of chronic renal failure. Acute elevations in intracellular adenosine 3′,5′-cyclic monophosphate (cAMP)…”
Get full text

Ionic permeabilities of rat renal cortical brush-border membrane vesicles by Lipkowitz, M S, Abramson, R G

“…It is generally assumed that electrolytes equilibrate readily across renal cortical brush-border membrane vesicles (BBMV). This assumption was tested by use of…”
Get full text

Carrier-mediated concentrative urate transport in rat renal membrane vesicles by Abramson, R G, Lipkowitz, M S

“…[2-14C]Urate uptake and efflux were studied in brush border and basolateral membrane vesicles of rat renal cortex that were exposed to 20 microM copper…”
Get full text

Reconstitution of hepatic uricase in planar lipid bilayer reveals a functional organic anion channel by Leal-Pinto, E, London, R D, Knorr, B A, Abramson, R G

“…Rat renal proximal tubule cell membranes have been reported to contain uricase-like proteins that function as electrogenic urate transporters. Although…”
Get full text

Modulation of ionic permeability in a nonpolarized cell: effect of cAMP by London, R D, Lipkowitz, M S, Sinert, R H, Abramson, R G

“…To evaluate whether adenosine 3',5'-cyclic monophosphate (cAMP) modulates ionic permeabilities of nonpolarized cells, as reported in diverse polarized…”
Get full text

State involvement in medical technology assessment by Mendelson, D N, Abramson, R G, Rubin, R J

“…State governments are reevaluating their role in the assessment of medical technologies. This paper outlines a range of state technology assessment activities,…”
Get full text

Colchicine therapy of the renal amyloidosis of ulcerative colitis by Meyers, S, Janowitz, H D, Gumaste, V V, Abramson, R G, Berman, L J, Venkataseshan, V S, Dickman, S H

“…Two patients with severe proteinuria, due to renal amyloidosis complicating chronic ulcerative colitis, improved remarkably with colchicine therapy. One…”
Get more information

Evidence for the transport function of uricase, an oxidative enzyme by Pordy, W T, Lipkowitz, M S, Abramson, R G

“…[2-14C]urate uptake was examined in proteoliposomes prepared with phosphatidylcholine and either pig liver uricase or albumin, and in protein-free liposomes…”
Get full text

Differential binding of folates by rat renal cortex brush border and basolateral membrane preparations by Corrocher, R, Abramson, R G, King, V F, Schreiber, C, Dikman, S, Waxman, S

“…The binding of radioactive 5-methyltetrahydrofolate and folic acid was found to be greater in brush border than in basolateral membrane preparations of rat…”
Get more information