Search Results - "Abramson, N. S."

Improved resuscitation outcome in emergency medical systems with increased usage of sodium bicarbonate during cardiopulmonary resuscitation by Bar-Joseph, G., Abramson, N. S., Kelsey, S. F., Mashiach, T., Craig, M. T., Safar, P.

“…Background:  The use of sodium bicarbonate (SB) in cardiopulmonary resuscitation (CPR) is controversial. This study analyzes the effects of SB use on CPR…”
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Recommended guidelines for uniform reporting of data from out-of-hospital cardiac arrest: the Utstein Style. A statement for health professionals from a task force of the American Heart Association, the European Resuscitation Council, the Heart and Stroke Foundation of Canada, and the Australian Resuscitation Council by Cummins, R O, Chamberlain, D A, Abramson, N S, Allen, M, Baskett, P J, Becker, L, Bossaert, L, Delooz, H H, Dick, W F, Eisenberg, M S

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Chemical Syntheses and Biological Activities of Lactam Analogues of α-Conotoxin SI by Hargittai, Balazs, Solé, Núria A, Groebe, Duncan R, Abramson, Stewart N, Barany, George

“…Bicyclization represents an effective method for the introduction of conformational constraints into small, biologically important peptides. Several strategies…”
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An Analog of Lophotoxin Reacts Covalently with Tyr190 in the α-Subunit of the Nicotinic Acetylcholine Receptor by Abramson, S N, Li, Y, Culver, P, Taylor, P

“…Lophotoxin and lophotoxin analog-1 are natural diterpenes from coral that inhibit nicotinic acetylcholine receptors by covalent reaction with the acetylcholine…”
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Old age does not negate good cerebral outcome after cardiopulmonary resuscitation: Analyses from the brain resuscitation clinical trials by Rogove, Herbert J, Safar, Peter, Sutton-Tyrrell, Kim, Abramson, Norman S

“…OBJECTIVETo assess survival after cardiac arrest and to determine whether age is an independent determinant of late mortality or poor neurologic outcome…”
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Neurotoxins distinguish between different neuronal nicotinic acetylcholine receptor subunit combinations by Luetje, C W, Wada, K, Rogers, S, Abramson, S N, Tsuji, K, Heinemann, S, Patrick, J

“…Neuronal and muscle nicotinic acetylcholine receptor subunit combinations expressed in Xenopus oocytes were tested for sensitivity to various neurotoxins…”
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Cardiopulmonary resuscitation: What cost to cheat death? by Lee, Kang H, Angus, Derek C, Abramson, Norman S

“…OBJECTIVESTo review the various outcomes from cardiopulmonary resuscitation (CPR), the factors that influence these outcomes, the costs associated with CPR,…”
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ACLS-does it really work? by Pepe, Paul E., Abramson, Norman S., Brown, Charles G.

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Actions of neurotoxins (bungarotoxins, neosurugatoxin and lophotoxins) on insect and nematode nicotinic acetylcholine receptors by Tornøe, C., Bai, D., Holden-Dye, L., Abramson, S.N., Sattelle, D.B.

“…Neurotoxins of natural origin have proved to be of considerable value in the isolation and characterization of vertebrate muscle and neuronal nicotinic…”
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Onchidal: a naturally occurring irreversible inhibitor of acetylcholinesterase with a novel mechanism of action by Abramson, S N, Radic, Z, Manker, D, Faulkner, D J, Taylor, P

“…Onchidal has been identified as the major lipid-soluble component of the defensive secretion of the mollusc Onchidella binneyi, and it has been proposed as the…”
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Irreversible inhibition of nicotinic acetylcholine receptors by the bipinnatins. Toxin activation and kinetics of receptor inhibition by GROEBE, D. R, DUMM, J. M, ABRAMSON, S. N

“…Bipinnatin-A, -B, and -C belong to a family of naturally occurring marine neurotoxins known as the lophotoxins. The lophotoxins are unique in that they…”
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Emergency cardiopulmonary bypass for resuscitation from prolonged cardiac arrest by Safar, P, Abramson, N S, Angelos, M, Cantadore, R, Leonov, Y, Levine, R, Pretto, E, Reich, H, Sterz, F, Stezoski, S W

“…After cardiac arrest (no flow) of more than approximately 5 minutes' duration, standard external cardiopulmonary resuscitation (CPR) basic, advanced, and…”
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Pathophysiologic and therapeutic implications of acid-base changes during CPR by von Planta, M, Bar-Joseph, G, Wiklund, L, Bircher, N G, Falk, J L, Abramson, N S

“…Acid-base changes occurring during cardiac arrest and subsequent CPR are related to a complex low-perfusion state characterized clinically by venous and tissue…”
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Lophotoxin and related coral toxins covalently label the alpha-subunit of the nicotinic acetylcholine receptor by Abramson, S N, Culver, P, Kline, T, Li, Y, Guest, P, Gutman, L, Taylor, P

“…Lophotoxin and lophotoxin analog-1 are uncharged cyclic diterpenes obtained from gorgonian corals. They have been shown to block the function of nicotinic…”
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Structure/activity and molecular modeling studies of the lophotoxin family of irreversible nicotinic receptor antagonists by Abramson, Stewart N, Trischman, Jacqueline A, Tapiolas, Dianne M, Harold, Edward E, Fenical, William, Taylor, Palmer

“…Lophotoxin is a small cyclic diterpene that irreversibly inhibits agonist binding to nicotinic acetylcholine receptors by reacting covalently with Tyr190 in…”
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Cerebral resuscitation from cardiac arrest: Treatment potentials by Gisvold, Sven-Eric, Sterz, Fritz, Abramson, Norman S, Bar-Joseph, Gad, Ebmeyer, Uwe, Gervais, Hendrik, Ginsberg, Myron, Katz, Laurence M, Kochanek, Patrick M, Kuboyama, Kazutoshi, Miller, Brian, Obrist, Walter, Roine, Risto O, Safar, Peter, Sim, Kah Ming, Vandevelde, Karol, White, Robert J, Xiao, Feng

“…In 1961, in Pittsburgh, PA, ``cerebral'' was added to the cardiopulmonary resuscitation system (CPR right arrow CPCR).Cerebral recovery is dependent on arrest…”
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Evaluation of models for analysis of radioligand binding data by Abramson, S N, McGonigle, P, Molinoff, P B

“…In the presence of agonists, many neurotransmitter receptors interact with regulatory components, resulting in the formation of a ternary complex composed of…”
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Properties of beta-adrenergic receptors of cultured mammalian cells. Interaction of receptors with a guanine nucleotide-binding protein in membranes prepared from L6 myoblasts and from wild-type and cyc- S49 lymphoma cells by Abramson, S N, Molinoff, P B

“…The radiolabeled agonist [3H]hydroxybenzylisoproterenol ([3H]HBI) and antagonist [125I]iodopindolol ([125I]IPIN) were used to investigate the properties of…”
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Irreversible Inhibitors of Nicotinic Acetylcholine Receptors: Isolation and Structural Characterization of the Biologically Active Solvolysis Products of Bipinnatin-A and Bipinnatin-C by Hyde, Edward G, Boyer, Arthur, Tang, Pei, Xu, Yan, Abramson, Stewart N

“…The lophotoxins irreversibly inhibit nicotinic acetylcholine receptors by covalent modification of Tyr190 in the alpha-subunits of the receptor. Previous…”
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Improving survival from sudden cardiac arrest : the chain of survival concept : a statement for health professionals from the advanced cardiac life support subcommittee and the emergency cardiac care committee, American heart association by Cummins, R O, Ornato, J P, Thies, W H, Pepe, P E

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