Search Results - "Abrams, S"

Management of hypertensive crisis: British and Irish Hypertension Society Position document by Kulkarni, Spoorthy, Glover, Mark, Kapil, Vikas, Abrams, S. M. L., Partridge, Sarah, McCormack, Terry, Sever, Peter, Delles, Christian, Wilkinson, Ian B.

“…Patients with hypertensive emergencies, malignant hypertension and acute severe hypertension are managed heterogeneously in clinical practice. Initiating…”
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How I treat refractory thrombotic thrombocytopenic purpura by Sayani, Farzana A., Abrams, Charles S.

“…Acquired thrombotic thrombocytopenic purpura (TTP) is characterized by thrombocytopenia and microangiopathic hemolytic anemia (MAHA) without an obvious cause,…”
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Impact of positive surgical margin length and Gleason grade at the margin on oncologic outcomes in patients with nonorgan‐confined prostate cancer by Preisser, Felix, Heinze, Alexander, S. Abrams‐Pompe, Raisa, Budäus, Lars, Chun, Felix K.‐H., Graefen, Markus, Huland, Hartwig, Tilki, Derya

“…Purpose Positive surgical margins (PSM) represent a poor prognostic factor at radical prostatectomy (RP). To investigate the impact of PSM, its length, the…”
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Roles of the Ras Raf MEK ERK pathway in leukemia therapy by Steelman, L S, Franklin, R A, Abrams, S L, Chappell, W, Kempf, C R, Bäsecke, J, Stivala, F, Donia, M, Fagone, P, Nicoletti, F, Libra, M, Ruvolo, P, Ruvolo, V, Evangelisti, C, Martelli, A M, McCubrey, J A

“…The Ras/Raf/mitogen-activated protein kinase (MEK)/extracellular signal-regulated kinase (ERK) pathway is often implicated in sensitivity and resistance to…”
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A Golgi Lipid Signaling Pathway Controls Apical Golgi Distribution and Cell Polarity during Neurogenesis by Xie, Zhigang, Hur, Seong Kwon, Zhao, Liang, Abrams, Charles S., Bankaitis, Vytas A.

“…Phosphatidylinositol (PtdIns) transfer proteins (PITPs) stimulate PtdIns-4-P synthesis and signaling in eukaryotic cells, but to what biological outcomes such…”
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Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K PTEN Akt mTOR pathway by Martelli, A M, Evangelisti, C, Chappell, W, Abrams, S L, Bäsecke, J, Stivala, F, Donia, M, Fagone, P, Nicoletti, F, Libra, M, Ruvolo, V, Ruvolo, P, Kempf, C R, Steelman, L S, McCubrey, J A

“…It has become apparent that regulation of protein translation is an important determinant in controlling cell growth and leukemic transformation. The…”
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How tumours escape mass destruction by Stewart, T J, Abrams, S I

“…It is now well established that the immune system can control neoplastic development and growth in a process termed immunosurveillance. A link between host…”
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60 Microlensing Events from the Three Years of Zwicky Transient Facility Phase One by Medford, Michael S., Abrams, Natasha S., Lu, Jessica R., Nugent, Peter, Lam, Casey Y.

“…Abstract Microlensing events have historically been discovered throughout the Galactic bulge and plane by surveys designed solely for that purpose. We conduct…”
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Overall Survival As the Outcome for Randomized Clinical Trials With Effective Subsequent Therapies by KORN, Edward L, FREIDLIN, Boris, ABRAMS, Jeffrey S

“…We review how overall survival (OS) comparisons should be interpreted with increasing availability of effective therapies that can be given subsequently to the…”
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Astrometric Microlensing by Primordial Black Holes with the Roman Space Telescope by Fardeen, James, McGill, Peter, Perkins, Scott E., Dawson, William A., Abrams, Natasha S., Lu, Jessica R., Ho, Ming-Feng, Bird, Simeon

“…Abstract Primordial black holes (PBHs) could explain some fraction of dark matter and shed light on many areas of early-Universe physics. Despite over half a…”
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Disentangling the Black Hole Mass Spectrum with Photometric Microlensing Surveys by Perkins, Scott E., McGill, Peter, Dawson, William, Abrams, Natasha S., Lam, Casey Y., Ho, Ming-Feng, Lu, Jessica R., Bird, Simeon, Pruett, Kerianne, Golovich, Nathan, Chapline, George

“…Abstract From the formation mechanisms of stars and compact objects to nuclear physics, modern astronomy frequently leverages surveys to understand populations…”
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ALCHEMIST Trials: A Golden Opportunity to Transform Outcomes in Early-Stage Non-Small Cell Lung Cancer by Govindan, Ramaswamy, Mandrekar, Sumithra J, Gerber, David E, Oxnard, Geoffrey R, Dahlberg, Suzanne E, Chaft, Jamie, Malik, Shakun, Mooney, Margaret, Abrams, Jeffrey S, Jänne, Pasi A, Gandara, David R, Ramalingam, Suresh S, Vokes, Everett E

“…The treatment of patients with metastatic non-small cell lung cancer (NSCLC) is slowly evolving from empirical cytotoxic chemotherapy to personalized treatment…”
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Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention by McCubrey, J A, Steelman, L S, Bertrand, F E, Davis, N M, Abrams, S L, Montalto, G, D'Assoro, A B, Libra, M, Nicoletti, F, Maestro, R, Basecke, J, Cocco, L, Cervello, M, Martelli, A M

“…Glycogen synthase kinase-3 (GSK-3) is well documented to participate in a complex array of critical cellular processes. It was initially identified in rat…”
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Nonparametric estimation of risk ratios for bivariate data by Abrams, S., Janssen, P., Swanepoel, J., Veraverbeke, N.

“…Inspired by the cross-ratio proposed by Clayton, we study a new risk ratio to describe the relation between the components of the random vector ( ). It is the…”
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Quantum Algorithm Providing Exponential Speed Increase for Finding Eigenvalues and Eigenvectors by Abrams, Daniel S., Lloyd, Seth

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Barriers to Service Use for Postpartum Depression Symptoms Among Low-Income Ethnic Minority Mothers in the United States by Abrams, Laura S., Dornig, Katrina, Curran, Laura

“…The risks of untreated postpartum depression (PPD) in the United States are higher among low-income ethnic minority mothers. However, research has not…”
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Digital Breast Tomosynthesis: Observer Performance Study by Gur, David, Abrams, Gordon S, Chough, Denise M, Ganott, Marie A, Hakim, Christiane M, Perrin, Ronald L, Rathfon, Grace Y, Sumkin, Jules H, Zuley, Margarita L, Bandos, Andriy I

“…The purpose of this study was to compare in a retrospective observer study the diagnostic performance of full-field digital mammography (FFDM) with that of…”
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Accuracy of circulating histones in predicting persistent organ failure and mortality in patients with acute pancreatitis by Liu, T., Huang, W., Szatmary, P., Abrams, S. T., Alhamdi, Y., Lin, Z., Greenhalf, W., Wang, G., Sutton, R., Toh, C. H.

“…Background Early prediction of acute pancreatitis severity remains a challenge. Circulating levels of histones are raised early in mouse models and correlate…”
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Statistical and practical considerations for clinical evaluation of predictive biomarkers by Polley, Mei-Yin C, Freidlin, Boris, Korn, Edward L, Conley, Barbara A, Abrams, Jeffrey S, McShane, Lisa M

“…Predictive biomarkers to guide therapy for cancer patients are a cornerstone of precision medicine. Discussed herein are considerations regarding the design…”
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COVID and crime: An early empirical look by Abrams, David S.

“…Data from 25 large U.S. cities is assembled to estimate the impact of the onset of the COVID-19 pandemic on crime. There is a widespread immediate drop in both…”
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