Search Results - "Abramowitz, Wattanaporn"

Lack of Pharmacokinetic or Pharmacodynamic Interaction Between Memantine and Donepezil by Periclou, Antonia P, Ventura, Daniel, Sherman, Tyler, Rao, Niranjan, Abramowitz, Wattanaporn T

“…BACKGROUND: Memantine, a low- to moderate-affinity, uncompetitive N-methyl-d-aspartate receptor antagonist, was approved in the US for treatment of moderate to…”
Get full text

An evaluation of the potential for pharmacokinetic interaction between escitalopram and the cytochrome P450 3A4 inhibitor ritonavir by Gutierrez, Marcelo M., Rosenberg, Jeffrey, Abramowitz, Wattanaporn

“…Background: Depression often coexists with a number of disease states, and patients with a diagnosis of depression often receive multiple medications. Thus, it…”
Get full text

Lack of Effect of a Single Dose of Ketoconazole on the Pharmacokinetics of Citalopram by Gutierrez, Marcelo, Abramowitz, Wattanaporn

“…Study Objective. To determine whether the pharmacokinetics of the antidepressant citalopram are affected by ketoconazole, a potent inhibitor of cytochrome P450…”
Get full text

Lack of Interaction Between Citalopram and the CYP3A4 Substrate Triazolam by Nolting, Arno, Abramowitz, Wattanaporn

“…Study Objectives. To determine the effect of the selective serotonin reuptake inhibitor citalopram on plasma levels of triazolam, and to determine the effect…”
Get full text

Pharmacokinetic study of memantine in healthy and renally impaired subjects by Periclou, Antonia, Ventura, Daniel, Rao, Niranjan, Abramowitz, Wattanaporn

“…Objective Our objective was to evaluate the pharmacokinetics of the Alzheimer's disease treatment memantine in subjects with normal and impaired renal…”
Get full text

A pharmacokinetic and dose-escalating study of paclitaxel injection concentrate for nano-dispersion (PICN) alone and with carboplatin in patients with advanced solid tumors by Ma, Wen Wee, Lam, Elaine Tat, Dy, Grace K., Diamond, Jennifer Robinson, Zhao, Yujie, Bui, Lynne A., Fetterly, Gerald J., Abramowitz, Wattanaporn, Harning, Ronald, Pencheva, Pepi, Bhowmik, Shravanti, Divekar, Ganesh Harishchandra, DiRaddo, Ann Marie, Eckhardt, S. Gail, Adjei, Alex A., Jimeno, Antonio

“…Abstract only 2557 Background: PICN is a novel Cremaphor-free composite of paclitaxel nano-particles stabilized with polymer and lipid using Nanotecton…”
Get full text

Investigation of the pharmacokinetic and pharmacodynamic interactions between memantine and glyburide/metformin in healthy young subjects: A single-center, multiple-dose, open-label study by Rao, Niranjan, Chou, Thomas, Ventura, Daniel, Abramowitz, Wattanaporn

“…The high prevalence rates of both 1026 Alzheimer's disease (AD) and type 2 diabetes mellitus in the elderly population suggest that concomitant pharmacotherapy…”
Get full text

Single-dose study to compare the pharmacokinetics of HFA flunisolide and CFC flunisolide by Nolting, Arno, Sista, Suryanarayana, Abramowitz, Wattanaporn

“…The hydrofluoroalkane (HFA) formulation of the inhaled corticosteroid flunisolide is a modification of the original chlorofluorocarbon (CFC) formulation. HFA…”
Get more information

Pharmacokinetic properties of combination oxycodone plus racemic ibuprofen: Two randomized, open-label, crossover studies in healthy adult volunteers by Kapil, Ram, Nolting, Arno, Roy, Partha, Fiske, William, Benedek, Irma, Abramowitz, Wattanaporn

“…As part of ongoing studies to evaluate the analgesic efficacy and pharmacokinetic properties of combination oxycodone plus ibuprofen in the treatment of…”
Get full text

Steady-State Pharmacokinetics of Citalopram in Young and Elderly Subjects by Gutierrez, Marcelo, Abramowitz, Wattanaporn

“…Study Objectives. To compare the steady‐state pharmacokinetics of citalopram after multiple‐dose administration in elderly and young subjects, and to correlate…”
Get full text

Effect of azole antifungals ketoconazole and fluconazole on the pharmacokinetics of dexloxiglumide by Jakate, Abhijeet S., Roy, Partha, Patel, Alpita, Abramowitz, Wattanaporn, Persiani, Stefano, Wangsa, Julie, Kapil, Ram

“…Aims Dexloxiglumide is a new CCK1 receptor antagonist under investigation for treatment of functional gastrointestinal disorders and is metabolized by CYP3A4…”
Get full text

Pharmacokinetic comparison of oral solution and tablet formulations of citalopram: a single-dose, randomized, crossover study by Gutierrez, Marcelo M., Abramowitz, Wattanaporn

“…Background: Citalopram tablets fulfill most dosing needs in the treatment of depression, but some patients may have difficulty swallowing tablets and thus may…”
Get full text

Multiple-dose proportionality study of flunisolide hydrofluoroalkane by Nolting, Arno, Abramowitz, Wattanaporn

“…The hydrofluoroalkane (HFA) formulation of the inhaled corticosteroid flunisolide is a modification of the original chlorofluorocarbon formulation. HFA…”
Get more information

Effect of Multiple-Dose Dexloxiglumide on the Pharmacokinetics of Oral Contraceptives in Healthy Women by Roy, Partha, Jakate, Abhijeet S., Patel, Alpita, Abramowitz, Wattanaporn, Wangsa, Julie, Persiani, Stefano, Kapil, Ram

“…This study was undertaken to evaluate the effect of dexloxiglumide, a selective cholecystokinin receptor antagonist, on the pharmacokinetics of a combination…”
Get full text

Flunisolide HFA vs flunisolide CFC: pharmacokinetic comparison in healthy volunteers by Nolting, Arno, Sista, Suryanarayana, Abramowitz, Wattanaporn

“…Two preparations of flunisolide, an inhaled corticosteroid, were compared in a parallel, multiple‐dose study of 31 healthy volunteers. The new flunisolide…”
Get full text

Pharmacokinetics of flunisolide administered via metered dose inhaler with and without a spacer device and following oral administration by Dickens, G R, Wermeling, D P, Matheny, C J, John, W, Abramowitz, W, Sista, S M, Foster, T, Choudhury, S

“…After inhalation of a glucocorticoid from a meter dose inhaler (MDI), a certain portion of the delivered dose is deposited in the lungs, and the remainder is…”
Get more information

Gastrointestinal transit of nondisintegrating, nonerodible oral dosage forms in pigs by MOHAMMAD HOSSAIN, ABRAMOWITZ, W, WATROUS, B. J, SZPUNAR, G. J, AYRES, J. W

“…Gastrointestinal (GI) transit data necessary as "baseline" or "control" information were collected using pigs as animal models preliminary to bioavailability…”
Get full text

Deposition and pharmacokinetics of flunisolide delivered from pressurized inhalers containing non-CFC and CFC propellants by Richards, J, Hirst, P, Pitcairn, G, Mahashabde, S, Abramowitz, W, Nolting, A, Newman, S P

“…Our objective was to assess the deposition and pharmacokinetics of a novel formulation of flunisolide (Aerobid, Forest Laboratories) in hydrofluoroalkane (HFA)…”
Get more information