Search Results - "Abram, Timothy J"
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A modular microarray imaging system for highly specific COVID-19 antibody testing
Published in Lab on a chip (21-09-2020)“…To detect the presence of antibodies in blood against SARS-CoV-2 in a highly sensitive and specific manner, here we describe a robust, inexpensive ($200),…”
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A Protein Microarray-Based Respiratory Viral Antigen Testing Platform for COVID-19 Surveillance
Published in Biomedicines (01-09-2022)“…High-throughput and rapid screening testing is highly desirable to effectively combat the rapidly evolving COVID-19 pandemic co-presents with influenza and…”
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Risk Stratification of Oral Potentially Malignant Disorders in Fanconi Anemia Patients Using Autofluorescence Imaging and Cytology-On-A Chip Assay
Published in Translational oncology (01-04-2018)“…Fanconi anemia (FA) is a hereditary genomic instability disorder with a predisposition to leukemia and oral squamous cell carcinomas (OSCCs). Hematopoietic…”
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Rapid bacterial detection and antibiotic susceptibility testing in whole blood using one-step, high throughput blood digital PCR
Published in Lab on a chip (07-02-2020)“…Sepsis due to antimicrobial resistant pathogens is a major health problem worldwide. The inability to rapidly detect and thus treat bacteria with appropriate…”
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An ultrasensitive test for profiling circulating tumor DNA using integrated comprehensive droplet digital detection
Published in Lab on a chip (13-03-2019)“…Current cancer detection systems lack the required sensitivity to reliably detect minimal residual disease (MRD) and recurrence at the earliest stages when…”
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Innovative Programmable Bio-Nano-Chip Digitizes Biology Using Sensors That Learn Bridging Biomarker Discovery and Clinical Implementation
Published in Frontiers in public health (22-05-2017)“…The lack of standard tools and methodologies and the absence of a streamlined multimarker approval process have hindered the translation rate of new biomarkers…”
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A rapid, point-of-care antibiotic susceptibility test for urinary tract infections
Published in Journal of medical microbiology (01-01-2020)“…The alarming rise in urinary tract infection (UTI) antimicrobial resistance has resulted from a combination of high prevalence, low specificity and the lack of…”
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Rapid isolation of rare targets from large fluid volumes
Published in Scientific reports (27-07-2020)“…Rapidly isolating rare targets from larger, clinically relevant fluid volumes remains an unresolved problem in biomedicine and diagnosis. Here, we describe how…”
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Characterization of the porosity in TRISO coated fuel particles and its effect on the relative thermal diffusivity
Published in Nuclear engineering and design (01-12-2013)“…•Identification of the porosity in 3D using Image Based Modelling (IBM).•The porosity volume fractions are varied 15.2–25.9vol% in TRISO particles.•Comparison…”
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Development of a cytology-based multivariate analytical risk index for oral cancer
Published in Oral oncology (01-05-2019)“…•An accurate Multivariate Analytical Risk Index for Oral Cancer has been developed.•Accuracy ranged from 76.0–82.4–89.6% for benign, dysplastic, malignant…”
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‘Cytology-on-a-chip’ based sensors for monitoring of potentially malignant oral lesions
Published in Oral oncology (01-09-2016)“…Highlights • Cytology-on-chip approach permits rapid molecular and morphometric analysis. • Stable, robust predictive models created from single-cell data. •…”
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Selective area laser deposition of FCC beta silicon carbide
Published in Crystal research and technology (1979) (01-07-2016)“…Silicon Carbide (SiC) has been deposited onto an alumina substrate by the thermal decomposition of the gaseous precursor tetramethylsilane (TMS). A 500 W…”
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The chemical durability of glass and graphite–glass composite doped with cesium oxide
Published in Journal of nuclear materials (01-01-2013)“…The role of temperature in determining the chemical stability of a waste form, as well as its leach rate, is very complex. This is because the dissolution…”
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Abstract LB-248: Minimally-invasive “cytology-on-chip” assay combined with continuous risk index for screening and surveillance of oral cancer in patients with Fanconi anemia
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Abstract Fanconi Anemia (FA) is an autosomal recessive disorder caused by mutations of DNA repair genes. The risk of oral cancer (OC) among FA patients is…”
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The chemical durability of glass and graphiteaglass composite doped with cesium oxide
Published in Journal of nuclear materials (01-01-2013)“…The role of temperature in determining the chemical stability of a waste form, as well as its leach rate, is very complex. This is because the dissolution…”
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Interobserver agreement in dysplasia grading: toward an enhanced gold standard for clinical pathology trials
Published in Oral surgery, oral medicine, oral pathology and oral radiology (01-10-2015)“…Objective Interobserver agreement in the context of oral epithelial dysplasia (OED) grading has been notoriously unreliable and can impose barriers for…”
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Risk Stratification of Oral Potentially Malignant Disorders in Fanconi Anemia Patients Using Autofluorescence Imaging and Cytology-On-A Chip Assay12
Published in Translational oncology (24-02-2018)“…Fanconi anemia (FA) is a hereditary genomic instability disorder with a predisposition to leukemia and oral squamous cell carcinomas (OSCCs). Hematopoietic…”
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