Search Results - "Abrahamsson, P A"
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Guidance on the use of bisphosphonates in solid tumours: recommendations of an international expert panel
Published in Annals of oncology (01-03-2008)“…Bisphosphonates (BP) prevent, reduce, and delay cancer-related skeletal complications in patients, and have substantially decreased the prevalence of such…”
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New considerations for ADT in advanced prostate cancer and the emerging role of GnRH antagonists
Published in Prostate cancer and prostatic diseases (01-03-2013)“…Androgen deprivation therapy (ADT) is first-line treatment for metastatic prostate cancer (PCa). Gonadotrophin-releasing hormone (GnRH) agonists are the most…”
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Neuroendocrine cells in tumour growth of the prostate
Published in Endocrine-related cancer (01-12-1999)“…The prognostic significance of neuroendocrine differentiation in prostatic malignancy is controversial, but the results of recent studies with markers such as…”
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Three‐month neoadjuvant hormonal therapy before radical prostatectomy: a 7‐year follow‐up of a randomized controlled trial
Published in BJU international (01-10-2002)“…Objective To describe the outcome, assessed as the level of prostate specific antigen (PSA), of a mature (more than half the events recorded) prospective…”
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Expression of serotonin receptors and role of serotonin in human prostate cancer tissue and cell lines
Published in The Prostate (15-05-2004)“…BACKGROUND Increase in the number of serotonin (5‐HT) releasing neuroendocrine (NE) cells has been shown to be correlated with tumor progression, loss of…”
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Clinical trial update and novel therapeutic approaches for metastatic prostate cancer
Published in Current medicinal chemistry (01-10-2011)“…Recurrent prostate cancer (PCa) remains a major clinical challenge. Invasive and metastatic PCa lesions often exhibit a partial and time-limited response to…”
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AKT and AMPK activation after high-fat and high-glucose in vitro treatment of prostate epithelial cells
Published in Hormone and metabolic research (01-06-2014)“…Considering the increasing consumption of saturated fat and glucose in diets worldwide and its possible association to carcinogenesis, this investigation…”
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Neuroendocrine differentiation in prostatic carcinoma
Published in The Prostate (01-05-1999)“…BACKGROUND Information is presented on prostatic neuroendocrine cells and neuroendocrine differentiation in prostatic carcinoma. The prognostic and therapeutic…”
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Expression of Serotonin Receptors 2B and 4 in Human Prostate Cancer Tissue and Effects of Their Antagonists on Prostate Cancer Cell Lines
Published in European urology (01-06-2005)“…Overexpression of receptors to neuroendocrine (NE) cell products has been suggested to contribute to development of hormone-refractory prostate cancer (HRPC)…”
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Neuroendocrine pathogenesis in adenocarcinoma of the prostate
Published in Annals of oncology (2001)“…In the prostate, the importance of sex hormones for its normal development and function is well known. However, it has been proposed that various…”
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Regressive changes and neuroendocrine differentiation in prostate cancer after neoadjuvant hormonal treatment
Published in The Prostate (01-03-2000)“…BACKGROUND We studied the extent of neuroendocrine (NE) tumor cell differentiation and its relation to regressive changes in prostate cancer after 3‐month…”
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No association between mutations in the human androgen receptor GGN repeat and inter‐sex conditions
Published in Molecular human reproduction (01-07-2003)“…The functional role of the GGN repeat in the human androgen receptor gene is unknown, although mutations in this region have been found in patients with…”
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Risks and Benefits of Hormonal Manipulation as Monotherapy or Adjuvant Treatment in Localised Prostate Cancer
Published in European urology (01-12-2005)“…A round table meeting was held to discuss the role of hormonal therapy in localised prostate cancer. The findings of the group were that immediate hormonal…”
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Neuroendocrine Differentiation in Prostatic Carcinoma During Hormonal Treatment
Published in Urology (Ridgewood, N.J.) (01-04-1998)“…Objectives. Neuroendocrine differentiation (NED) is a common feature in adenocarcinoma of the prostate. Several studies suggest that NED may have a major…”
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Treatment of locally advanced prostate cancer--a new role for antiandrogen monotherapy?
Published in European urology (2001)“…Men with locally advanced prostate cancer face a high risk of disease progression and cancer-related death. The traditional active treatment options for…”
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Free, complexed and total serum prostate specific antigen: the establishment of appropriate reference ranges for their concentrations and ratios
Published in The Journal of urology (01-09-1995)“…Prostate specific antigen (PSA) exists in the serum in several molecular forms that can be measured by immunodetectable assays: free PSA, PSA complexed to…”
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Semenogelin, the predominant protein in human semen. Primary structure and identification of closely related proteins in the male accessory sex glands and on the spermatozoa
Published in The Journal of biological chemistry (25-01-1989)“…The predominant protein in human semen, semenogelin, was characterized by lambda gt11 clones isolated from a seminal vesicular cDNA library. One clone,…”
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Octreotide scintigraphy and Chromogranin A do not predict clinical response in patients with octreotide acetate-treated hormone-refractory prostate cancer
Published in Prostate cancer and prostatic diseases (01-03-2006)“…In this pilot study, the predictive value of Octreotide scintigraphy (Octreoscan) and/or Chromogranin-A (CgA) was investigated in patients with…”
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