Search Results - "Abraham, Linu"

An alpha-catulin homologue controls neuromuscular function through localization of the dystrophin complex and BK channels in Caenorhabditis elegans by Abraham, Linu S, Oh, Hyun J, Sancar, Feyza, Richmond, Janet E, Kim, Hongkyun

“…The large conductance, voltage- and calcium-dependent potassium (BK) channel serves as a major negative feedback regulator of calcium-mediated physiological…”
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Adult Philadelphia-Positive Acute Lymphoblastic Leukemia: A Single-Institution Experience in Limited-Resource Setting by Antapura, Rudresha Haleshappa, Vaibhav, Amale Baburao, Dasappa, Lokanatha, Jacob, Linu Abraham, Sureshbabu, Mallekavu Channappa, Lokesh, Kadabur Nagendrappa, Rajeev, Lakkavalli Krishnappa, Saldanha, Smitha C., Venkatesh, Tirumala

“…Background Adult Philadelphia-positive (Ph + ) acute lymphoblastic leukemia (ALL) is a distinct entity with poor prognosis. Treatment with tyrosine kinase…”
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Socioeconomic and administrative factors associated with treatment delay of esophageal and gastric carcinoma: Prospective study from a tertiary care centre in a developing country by Lokanatha, D., Hassan, Syed Adil, Jacob, Linu Abraham, Suresh Babu, M.C., Lokesh, K.N., Rudresha, A.H., Rajeev, L.K., Saldanha, Smitha, Thottian, Antony G.F.

“…•Median time interval from onset of first symptoms to start of treatment in our study population was 15 weeks.•Per capita income and educational level of the…”
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Role of prephase treatment prior to definitive chemotherapy in patients with diffuse large B‐cell lymphoma by Lakshmaiah, K C, Asati, Vikas, Babu K, Govind, D, Lokanath, Jacob, Linu Abraham, M C, Suresh Babu, K N, Lokesh, L K, Rajeev, A H, Rudresh, Saldanha, Smitha, Koppaka, Deepak, Patidar, Rajesh, C S, Premalata

“…Background During the treatment of diffuse large B‐cell lymphoma (DLBCL) patients, treatment‐related toxicities are higher in the initial phase of treatment…”
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Treatment patterns and comparative analysis of non-intensive regimens in elderly acute myeloid leukemia patients—a real-world experience from India by Kanakasetty, Govind B., R, Chethan, K C, Lakshmaiah, Dasappa, Lokanatha, Jacob, Linu Abraham, M C, Suresh Babu, K N, Lokesh, Haleshappa, Rudresha Antapura, L K, Rajeev, Saldanha, Smitha Carol, Deepak, Koppaka, Rajesh, Patidar, Asati, Vikas

“…Elderly patients with acute myeloid leukemia have a poor prognosis. Data from developing countries is sparse in the literature. In this retrospective study,…”
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Presynaptic BK channel localization is dependent on the hierarchical organization of alpha-catulin and dystrobrevin and fine-tuned by CaV2 calcium channels by Oh, Kelly H, Abraham, Linu S, Gegg, Chandler, Silvestri, Christian, Huang, Yung-Chi, Alkema, Mark J, Furst, Jacob, Raicu, Daniela, Kim, Hongkyun

“…Large conductance, calcium-activated BK channels regulate many important physiological processes, including smooth muscle excitation, hormone release and…”
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Selective MCL-1 inhibitor ABBV-467 is efficacious in tumor models but is associated with cardiac troponin increases in patients by Yuda, Junichiro, Will, Christine, Phillips, Darren C., Abraham, Linu, Alvey, Cory, Avigdor, Abraham, Buck, Wayne, Besenhofer, Lauren, Boghaert, Erwin, Cheng, Dong, Cojocari, Dan, Doyle, Kelly, Hansen, T. Matthew, Huang, Kevin, Johnson, Eric F., Judd, Andrew S., Judge, Russell A., Kalvass, John C., Kunzer, Aaron, Lam, Lloyd T., Li, Rachel, Martin, Ruth L., Mastracchio, Anthony, Mitten, Mike, Petrich, Adam, Wang, Jin, Ward, James E., Zhang, Haichao, Wang, Xilu, Wolff, Johannes E., Bell-McGuinn, Katherine M., Souers, Andrew J.

“…Background MCL-1 is a prosurvival B-cell lymphoma 2 family protein that plays a critical role in tumor maintenance and survival and can act as a resistance…”
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Rapidly Progressing Plasma Cell Leukemia with Underlying Plasmablastic Morphology: A Rare Case Report of a 25-Year Old Male by Saldanha, Smitha, Goyal, Shina, Dasappa, Lokanatha, Jacob, Linu Abraham, Babu, M C Suresh, Lokesh, K N, Rudresha, A H, Rajeev, L K, Madhumathi, D S

“…Multiple myeloma constitutes a wide spectrum of diseases, ranging from slow-growing monoclonal gammopathy of undetermined significance to rapidly progressing…”
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Expression of Aberrant Markers and its Association with Remission Postinduction Therapy in Acute Lymphoblastic Leukaemia and Acute Myeloid Leukaemia by Shwetha, Subbaramaiah, Lokanatha, Dasappa, Sureshbabu, MC, Lokesh, KN, Rudresha, AH, Rajeev, LK, Saldanha, Smitha C, Jacob, Linu Abraham

“…Introduction: Haematological malignancies contribute to a significant number (8.2%) among cancer patientsin India. Bursa-Acute Lymphoblastic Leukaemia (B-ALL),…”
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Pre-phase strategy to mitigate first cycle effect in diffuse large B cell lymphoma by Rudresha, A. H, Hassan, Syed Adil, Sreevalli, A, Lokanatha, D, Babu, M. C. Suresh, Lokesh, K. N, Rajeev, L. K

“…Context Treatment-related toxicities in DLBCL (diffuse large B cell lymphoma) patients are higher in the initial phase of treatment (first cycle effect)…”
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Glutathione is essential for early embryogenesis – Analysis of a glutathione synthetase knockout mouse by Winkler, Andreas, Njålsson, Runa, Carlsson, Katarina, Elgadi, Abdelaziz, Rozell, Björn, Abraham, Linu, Ercal, Nuran, Shi, Zheng-Zheng, Lieberman, Michael W., Larsson, Agne, Norgren, Svante

“…► Mice homozygous for the knockout of glutathione synthetase die in utero. ► Heterozygous mice survive without distinct phenotype. ► Gamma-glutamylcysteine…”
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Follicular Lymphoma in Young Adults: Study from a Regional Cancer Center in South India by Rudreshaa, A. H., Goyal, Shina, Lokanatha, D., Jacob, Linu Abraham, Lokesh, K. N., Saldanha, Smitha, Sansar, Bipinesh, Rajeev, L. K.

“…Abstract Objective Follicular lymphoma (FL) is a disease of the elderly. It is postulated that younger patients have distinct tumor biology and treatment…”
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Interaction of α-Catulin with Dystrobrevin Contributes to Integrity of Dystrophin Complex in Muscle by Oh, Hyun J., Abraham, Linu S., van Hengel, Jolanda, Stove, Christophe, Proszynski, Tomasz J., Gevaert, Kris, DiMario, Joseph X., Sanes, Joshua R., van Roy, Frans, Kim, Hongkyun

“…The dystrophin complex is a multimolecular membrane-associated protein complex whose defects underlie many forms of muscular dystrophy. The dystrophin complex…”
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A Pilot Study on the Addition of Tramadol or Eutectic Mixture of Local Anesthetics (Prilocaine Plus Lignocaine) to Local Lignocaine Infiltration for Prevention of Bone Marrow Aspiration/Biopsy Associated Pain by Rudresha, AH, Sansar, Bipinesh, Lokanath, D., Jacob, Linu Abraham, Babu, M.C. Suresh, Lokesh, K. N., Saldanha, Smitha C., Goyal, Shina, Rajeev, L. K.

“…Abstract Objectives Bone marrow aspiration although being a common procedure is associated with significant pain and its reduction remains an unmet need. We…”
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Chronic myeloid leukemia in children and adolescents: results of treatment with imatinib mesylate by Lakshmaiah, K. C., Bhise, Rohan, Purohit, Samit, Abraham, Linu J., Lokanatha, D., Suresh, T. M., Appaji, L., Arunakumari, B. S., Govindbabu, K.

“…Abstract Chronic myeloid leukemia (CML) is a rare disease in children, accounting for 2-3% of leukemias in this age group. Few studies have reported on…”
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Predictive & Prognostic Implications of Variant Philadelphia Translocations in CML – Experience from a Tertiary Oncology Centre in Southern India by Babu Kanakasetty, Govind, Dr, Kuntejowdahalli, Lakshmaiah, Dr, Harsh Thanky, Aditi, Dr, Dasappa, Lokanatha, Dr, Jacob, Linu Abraham, Dr, Mallekavu, Suresh Babu, Dr, Kumari, Prasanna, Dr

“…Abstract Inroduction Chronic Myeloid Leukemia (CML) is a Myeloproliferative disorder characterised by Philadelphia (Ph) chromosome with classical…”
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CML in Elderly: Does Age Matter? by Lokesh, Kadabur Nagendrappa, Pehalajani, Jitendra Kumar, Loknatha, Dassappa, Jacob, Linu Abraham, Babu, M. C. Suresh, Rudresha, A. H., Rajeev, Lakkavalli Krishnappa, Smitha, S. C., Ashok, Khandare Pravin, Madhumathi, D. S.

“…The median age of diagnosis for chronic myeloid leukemia (CML) in India is 35 years on the contrary to western literature which is 47 years. The outcome of the…”
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Primary mucinous carcinomas of the lung: Clinical characteristics and treatment outcomes by Rajeev, L, Thottian, Antony, Amirtham, Usha, Lokanatha, D, Jacob, Linu, Babu, M, Lokesh, K, Rudresha, A, Saldanha, Smitha, Hassan, Syed

“…Introduction: Invasive mucinous adenocarcinoma (IMA) of the lung is a distinct histologic variant of adenocarcinomas comprising about 2%-10% of lung…”
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Clinicopathological Profile of Pure Neuroendocrine Neoplasms of the Esophagus: A South Indian Center Experience by Saldanha, Smitha Carol, Kumar, Rekha V., Lokesh, K. N., Rajeev, Lakkavalli Krishnappa, Babu, Suresh, Jacob, Linu A., Kamath, Mangesh, Lakshmaiah, Kuntegowdanahalli Chinnagiriyappa, Lokanatha, D., Babu, Govind, Haleshappa, Rudresha Antapura

“…Purpose. Neuroendocrine neoplasms (NENs) of the esophagus are very uncommon with only a few studies published worldwide. Studies on clinical profile,…”
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Clinico-Pathological Significance and Prognostic Impact of Various PML RARA Transcripts on Outcomes in Acute Promyelocytic Myeloid Leukemia (APML) Treated with Single Agent Arsenic Trioxide(ATO)- Insights from a Tertiary Cancer Center in South India by Sindhusha, K, C Saldanha, Smitha, Abraham Jacob, Linu, Suresh Babu, M.C., Lokesh, K. N., Rudresha, A. H., Rajeev, L. K.

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