Search Results - "Abplanalp, W T"

Loss of Y-chromosomal genes in macrophages induces paracrine phenotypic alterations in cardiac cells by Zanders, L, Fleck, F, Shumliakivska, M, Abplanalp, W T, Zeiher, A M, Dimmeler, S

“…Abstract Background At the intersection of gender medicine and ageing, mosaic loss of the Y chromosome (mLoY) in hematopoietic cells has emerged as a novel…”
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Human, mouse scRNA-seq and flow cytometry data in ischemic heart failure models predict immune cell activation signatures with altered endothelial cell cross talk by Merten, M, Rasper, T, Cremer, S, Schuhmacher, B, Tombor, L, Zeiher, A M, Hoffmann, J, Abplanalp, W T, Dimmeler, S

“…Abstract   Chronic ischemic Heart Failure (HF) with reduced ejection fraction is marked by adverse remodelling and sustained inflammation. The effects of…”
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Interaction of inherited genetic variants in the NLRP3 inflammasome/IL-6 pathway with acquired clonal hematopoiesis to modulate mortality risk in patients with HFrEF by Cremer, S, Katsaouni, N, Abplanalp, W T, Berkowitsch, A, Kirschbaum, K, Rieger, M, Rapp, S, Wild, P, Dimmeler, S, Schulz, M, Zeiher, A

“…Abstract Aims Clonal hematopoiesis (CH), defined as the presence of an expanded somatic blood cell clone due to acquired mutations in leukemia driver genes,…”
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Atherosclerosis licenses for an exceeding immune response in COVID-19 disease by Leberzammer, J, Abplanalp, W T, Glaser, S F, Schumacher, B, Merten, M, Katschke, M T, John, D, Vehreschild, M, Zeiher, A, Dimmeler, S, Cremer, S

“…Abstract Background COVID-19 is characterized by emergency hematopoiesis with a dysregulated myeloid compartment, comprising proinflammatory and…”
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Vascular senescence controls the neuro-cardiac interface in the aging heart by Wagner, J, Tombor, L S, Malacarne, P F, Abplanalp, W T, John, D, Angendohr, S, Scherschel, K, Meyer, C, Clauss, S, Baer, C, Osmanagic-Myers, S, Zeiher, A M, Brandes, R P, Luxan, G, Dimmeler, S

“…Abstract Aging is a major risk factor for impaired cardiovascular function. The aging heart is characterized by vascular dysfunction, increased hypertrophy,…”
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The human cell atlas of the hypertrophic heart reveals impaired inter-cellular cross-talks by Nicin, L, Bruening, R S, Kattih, B, Glaser, S F, Abplanalp, W T, Schroeter, S M, Arsalan, M, Holubec, T, Emrich, F, Meder, B, Reich, C, Walther, T, Zeiher, A M, John, D, Dimmeler, S

“…Abstract Introduction The pathophysiology of cardiac hypertrophy is multifactorial and is accompanied by the dysregulation of various signaling pathways…”
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