Search Results - "Abourehab, Mohammed A.S."
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New opportunities for RGD-engineered metal nanoparticles in cancer
Published in Molecular cancer (25-05-2023)“…The advent of nanotechnology has opened new possibilities for bioimaging. Metal nanoparticles (such as gold, silver, iron, copper, etc.) hold tremendous…”
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2
Unveiling Antimicrobial and Antioxidant Compositional Differences between Dukkah and Za’atar via SPME-GCMS and HPLC-DAD
Published in Molecules (Basel, Switzerland) (01-10-2022)“…Interest in plant-based diets has been on the rise in recent years owing to the potential health benefits of their individual components and the notion that…”
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3
Hyaluronic acid decorated tacrolimus-loaded nanoparticles: Efficient approach to maximize dermal targeting and anti-dermatitis efficacy
Published in Carbohydrate polymers (01-10-2018)“…[Display omitted] •Nano-delivery systems have extensively been employed for target-specific delivery.•Hyaluronic acid modified tacrolimus-loaded nanoparticles…”
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Hyaluronic Acid Modified Risedronate and Teriparatide Co-loaded Nanocarriers for Improved Osteogenic Differentiation of Osteoblasts for the Treatment of Osteoporosis
Published in Current pharmaceutical design (01-01-2019)“…Owing to its multifactorial intricate pathogenesis, combined therapeutic regimen is considered appropriate for the treatment of osteoporosis. However, a…”
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5
Ginger Extract-Loaded Transethosomes for Effective Transdermal Permeation and Anti-Inflammation in Rat Model
Published in International journal of nanomedicine (01-01-2023)“…Ginger extract (GE) has sparked great interest due to its numerous biological benefits. However, it suffers from limited skin permeability, which challenges…”
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6
Nanoemulgel, an Innovative Carrier for Diflunisal Topical Delivery with Profound Anti-Inflammatory Effect: in vitro and in vivo Evaluation
Published in International journal of nanomedicine (01-01-2021)“…Rheumatoid arthritis is an autoimmune disorder that directly affects joints. However, other body organs including heart, eyes, skin, blood vessels and lungs…”
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7
Measurement of metoprolol solubility in supercritical carbon dioxide; experimental and modeling study
Published in Case studies in thermal engineering (01-02-2023)“…Metoprolol is a beta-blocker agent, widely used to treat hypertension, and some heart diseases. However, due to low bioavailability and short half-life of this…”
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8
Self-assembled biodegradable polymeric micelles to improve dapoxetine delivery across the blood-brain barrier
Published in International journal of nanomedicine (01-01-2018)“…Dapoxetine (DPX) is the drug of choice for the specific treatment of premature ejaculation. DPX is characterized by relatively low bioavailability (42%) and…”
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Cubosomes as an emerging platform for drug delivery: a review of the state of the art
Published in Journal of materials chemistry. B, Materials for biology and medicine (13-04-2022)“…Lipid-based drug-delivery nanoparticles, including non-lamellar-type, mesophasic nanostructured materials of lyotropic liquid crystals (LLCs), have been a…”
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'Poly phenolic phytoceutical loaded nano-bilosomes for enhanced caco-2 cell permeability and SARS-CoV 2 antiviral activity': in-vitro and insilico studies
Published in Drug delivery (01-12-2023)“…Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) predisposed to the emergence of worldwide catastrophe that impels the evolution of safe and…”
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11
Boosting the anti MERS-CoV activity and oral bioavailability of resveratrol via PEG-stabilized emulsomal nano-carrier: Factorial design, in-vitro and in-vivo assessments
Published in Drug delivery (31-12-2022)“…Resveratrol (RSV) is a phytoceutical polyphenolic compound exhibiting a well evidenced wide range of therapeutic activities. Unfortunately, its diminished…”
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12
Self-emulsifying drug delivery systems as a tool to improve solubility and bioavailability of resveratrol
Published in Drug design, development and therapy (01-01-2016)“…Resveratrol is a nonflavonoid polyphenolic compound which has a broad range of desirable biological actions which include antioxidant, anti-inflammatory,…”
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13
Development of GC–MS/MS method for environmental monitoring of 49 pesticide residues in food commodities in Al-Rass, Al-Qassim region, Saudi Arabia
Published in Arabian journal of chemistry (01-11-2022)“…The harmful effects of pesticide residues are a threat to our health. Therefore, the current study aimed to validate a simple method for the determination of…”
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Solubility enhancement of decitabine as anticancer drug via green chemistry solvent: Novel computational prediction and optimization
Published in Arabian journal of chemistry (01-12-2022)“…Nowadays, supercritical fluid technology (SFT) has been an interesting scientific subject in disparate industrial-based activities such as drug delivery,…”
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15
Computational modeling of Hg/Ni ions separation via MOF/LDH nanocomposite: Machine learning based modeling
Published in Arabian journal of chemistry (01-12-2022)“…Nowadays, sustainable supplement of water has recently been identified as a vital necessity due to the existence of limited drinkable water sources. To do…”
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Exploring the volatile metabolites of three Chorisia species: Comparative headspace GC–MS, multivariate chemometrics, chemotaxonomic significance, and anti-SARS-CoV-2 potential
Published in Saudi pharmaceutical journal (01-05-2023)“…Chorisia (syn. Ceiba) species are important ornamental, economic, and medicinal plants that are endowed with a diversity of secondary metabolites; however,…”
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Exploitation the unique acidity of novel cerium-tungstate catalysts in the preparation of indole derivatives under eco-friendly acid catalyzed Fischer indole reaction protocol
Published in Arabian journal of chemistry (01-03-2022)“…Solid acidic cerium tungstate catalysts containing different molar ratios of cerium and tungstate were prepared by direct solvothermal methodology. The…”
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Evaluation of the effects of a dasatinib-containing, self-emulsifying, drug delivery system on HT29 and SW420 human colorectal carcinoma cells, and MCF7 human breast adenocarcinoma cells
Published in Journal of Taibah University Medical Sciences (01-08-2024)“…داساتينيب هو مثبط تيروزين كيناز من الجيل الثاني. إنه يعمل كدواء جزيء صغير متعدد الأهداف من خلال استهداف كينازات التيروزين المختلفة التي تشارك في نمو الخلايا…”
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Drug Polymeric Carrier of Aceclofenac Based on Amphiphilic Chitosan Micelles
Published in ACS omega (19-12-2023)“…Amphiphilic micelles based on chitosan (CS) were applied as drug carriers of aceclofenac (ACF) as a potential method to induce its bioavailability and…”
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Pyrrolizine/indolizine-cinnamaldehyde Schiff bases: Design, synthesis, biological evaluation, ADME, and molecular docking study
Published in European journal of medicinal chemistry reports (01-04-2022)“…In the present study, two new Schiff bases 10a,b were synthesized by the condensation of 9a,b with cinnamaldehyde. The chemical structures of 10a,b were…”
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