Search Results - "Abourehab, Mohammed A. S."

Advancements in nanoparticle-based treatment approaches for skin cancer therapy by Zeng, Leli, Gowda, B H Jaswanth, Ahmed, Mohammed Gulzar, Abourehab, Mohammed A S, Chen, Zhe-Sheng, Zhang, Changhua, Li, Jia, Kesharwani, Prashant

“…Skin cancer has emerged as the fifth most commonly reported cancer in the world, causing a burden on global health and the economy. The enormously rising…”
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Gold nanoparticles and gold nanorods in the landscape of cancer therapy by Kesharwani, Prashant, Ma, Ruiyang, Sang, Liang, Fatima, Mahak, Sheikh, Afsana, Abourehab, Mohammed A S, Gupta, Neelima, Chen, Zhe-Sheng, Zhou, Yun

“…Cancer is a grievous disease whose treatment requires a more efficient, non-invasive therapy, associated with minimal side effects. Gold nanoparticles…”
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Unravelling the enigma of siRNA and aptamer mediated therapies against pancreatic cancer by Liu, Zhe, Parveen, Neha, Rehman, Urushi, Aziz, Aisha, Sheikh, Afsana, Abourehab, Mohammed A S, Guo, Wei, Huang, Junhao, Wang, Zhenning, Kesharwani, Prashant

“…Pancreatic cancer (PC) is a fatal disease that has a poor 5-year survival rate. The poor prognosis can be attributed to both troublesome detections at the…”
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Introduction of benzyloxy pharmacophore into aryl/heteroaryl chalcone motifs as a new class of monoamine oxidase B inhibitors by Sudevan, Sachithra Thazhathuveedu, Oh, Jong Min, Abdelgawad, Mohamed A., Abourehab, Mohammed A. S., Rangarajan, T. M., Kumar, Sunil, Ahmad, Iqrar, Patel, Harun, Kim, Hoon, Mathew, Bijo

“…The inhibitory action of fifteen benzyloxy ortho / para -substituted chalcones ( B1-B15 ) was evaluated against human monoamine oxidases (hMAOs). All the…”
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Design, synthesis, in vitro biological assessment and molecular modeling insights for novel 3-(naphthalen-1-yl)-4,5-dihydropyrazoles as anticancer agents with potential EGFR inhibitory activity by Eldehna, Wagdy M., El Hassab, Mahmoud A., Elsayed, Zainab M., Al-Warhi, Tarfah, Elkady, Hazem, Abo-Ashour, Mahmoud F., Abourehab, Mohammed A. S., Eissa, Ibrahim H., Abdel-Aziz, Hatem A.

“…Currently, the humanity is in a fierce battle against various health-related challenges especially those associated with human malignancies. This created the…”
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Dostarlimab as a Miracle Drug: Rising Hope against Cancer Treatment by Singh, Vanshikha, Sheikh, Afsana, Abourehab, Mohammed A. S, Kesharwani, Prashant

“…Immunotherapy is one of the four pillars of cancer treatment that has recently emerged as a beacon of hope for cancer patients. Certain immunotherapies, for…”
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Influence of selected non-antibiotic pharmaceuticals on antibiotic resistance gene transfer in Escherichia coli by Mohamed, Doaa Safwat, Abd El-Baky, Rehab Mahmoud, El-Mokhtar, Mohamed Ahmed, Ghanem, Sahar K, Yahia, Ramadan, Alqahtani, Alaa M, Abourehab, Mohammed A S, Ahmed, Eman Farouk

“…Antibiotic resistance genes (ARGs) transfer rapidly among bacterial species all over the world contributing to the aggravation of antibiotic resistance crisis…”
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Advancements in Polymeric Nanocarriers to Mediate Targeted Therapy against Triple-Negative Breast Cancer by Fatima, Mahak, Sheikh, Afsana, Abourehab, Mohammed A S, Kesharwani, Prashant

“…Triple-negative breast cancer (TNBC) is a destructive disease with a poor prognosis, low survival rate and high rate of metastasis. It comprises 15% of total…”
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Development a novel robust method to enhance the solubility of Oxaprozin as nonsteroidal anti-inflammatory drug based on machine-learning by Abdelbasset, Walid Kamal, Elkholi, Safaa M., Ismail, Khadiga Ahmed, Alshehri, Sameer, Alobaida, Ahmed, Huwaimel, Bader, Alatawi, Ahmed D., Alsubaiyel, Amal M., Venkatesan, Kumar, Abourehab, Mohammed A. S.

“…Accurate specification of the drugs’ solubility is known as an important activity to appropriately manage the supercritical impregnation process. Over the last…”
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Ultrasound Assisted Synthesis and In Silico Modelling of 1,2,4-Triazole Coupled Acetamide Derivatives of 2-(4-Isobutyl phenyl)propanoic acid as Potential Anticancer Agents by Mahmood, Sadaf, Khan, Samreen Gul, Rasul, Azhar, Christensen, Jørn Bolstad, Abourehab, Mohammed A S

“…The development of an economical method for the synthesis of biologically active compounds was the major goal of this research. In the present study, we have…”
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Design of predictive model to optimize the solubility of Oxaprozin as nonsteroidal anti-inflammatory drug by Alshehri, Sameer, Alqarni, Mohammed, Namazi, Nader Ibrahim, Naguib, Ibrahim A., Venkatesan, Kumar, Mosaad, Yasser O., Pishnamazi, Mahboubeh, Alsubaiyel, Amal M., Abourehab, Mohammed A. S.

“…These days, many efforts have been made to increase and develop the solubility and bioavailability of novel therapeutic medicines. One of the most believable…”
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A Novel Curcumin Arginine Salt: A Solution for Poor Solubility and Potential Anticancer Activities by Fatease, Adel Al, Shoman, Mai E, Abourehab, Mohammed A S, Abou-Taleb, Heba A, Abdelkader, Hamdy

“…Curcumin is a natural polyphenolic compound with well-known anticancer properties. Poor solubility and permeability hamper its use as an anticancer…”
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Design, Formulation, and Characterization of Valsartan Nanoethosomes for Improving Their Bioavailability by Nasr, Ali M, Moftah, Fayrouz, Abourehab, Mohammed A. S, Gad, Shadeed

“…The objective of this study was to formulate and evaluate valsartan (VLT) ethosomes to prepare an optimized formula of VLT-entrapped ethosomes that could be…”
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Solubility Optimization of Loxoprofen as a Nonsteroidal Anti-Inflammatory Drug: Statistical Modeling and Optimization by Alqarni, Mohammed, Namazi, Nader Ibrahim, Alshehri, Sameer, Naguib, Ibrahim A, Alsubaiyel, Amal M, Venkatesan, Kumar, Elmokadem, Eman Mohamed, Pishnamazi, Mahboubeh, Abourehab, Mohammed A S

“…Industrial-based application of supercritical CO (SCCO ) has emerged as a promising technology in numerous scientific fields due to offering brilliant…”
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In Silico Study for Algerian Essential Oils as Antimicrobial Agents against Multidrug-Resistant Bacteria Isolated from Pus Samples by Aouf, Abdelhakim, Bouaouina, Sarah, Abdelgawad, Mohamed A, Abourehab, Mohammed A. S, Farouk, Amr

“…In the context of the globally growing problem of resistance to most used antibacterial agents, essential oils offer promising solutions against…”
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Development of GBRT Model as a Novel and Robust Mathematical Model to Predict and Optimize the Solubility of Decitabine as an Anti-Cancer Drug by Abdelbasset, Walid Kamal, Elsayed, Shereen H, Alshehri, Sameer, Huwaimel, Bader, Alobaida, Ahmed, Alsubaiyel, Amal M, Alqahtani, Abdulsalam A, El Hamd, Mohamed A, Venkatesan, Kumar, AboRas, Kareem M, Abourehab, Mohammed A. S

“…The efficient production of solid-dosage oral formulations using eco-friendly supercritical solvents is known as a breakthrough technology towards developing…”
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Computational simulation and target prediction studies of solubility optimization of decitabine through supercritical solvent by Alshahrani, Saad M., Almutairy, Bjad K., Alfadhel, Munerah M., Belal, Amany, Abourehab, Mohammed A. S., Saqr, Ahmed Al, Alshetaili, Abdullah S., Venkatesan, Kumar, Alsubaiyel, Amal M., Pishnamazi, Mahboubeh

“…Computational analysis of drug solubility was carried out using machine learning approach. The solubility of Decitabine as model drug in supercritical CO 2 was…”
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Natural resistance of tomato plants to Tomato yellow leaf curl virus by H El-Sappah, Ahmed, Qi, Shiming, A Soaud, Salma, Huang, Qiulan, M Saleh, Alaa, A S Abourehab, Mohammed, Wan, Lingyun, Cheng, Guo-Ting, Liu, Jingyi, Ihtisham, Muhammad, Noor, Zarqa, Rouf Mir, Reyazul, Zhao, Xin, Yan, Kuan, Abbas, Manzar, Li, Jia

“…Tomato yellow leaf curl virus (TYLCV) is one of the most harmful afflictions in the world that affects tomato growth and production. Six regular antagonistic…”
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Critical Analysis and Optimization of Stoichiometric Ratio of Drug-Coformer on Cocrystal Design: Molecular Docking, In Vitro and In Vivo Assessment by Dhibar, Manami, Chakraborty, Santanu, Basak, Souvik, Pattanayak, Paramita, Chatterjee, Tanmay, Ghosh, Balaram, Raafat, Mohamed, Abourehab, Mohammed A S

“…In this present research, an attempt has been made to address the influence of drug-coformer stoichiometric ratio on cocrystal design and its impact on…”
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Development of Halogenated-Chalcones Bearing with Dimethoxy Phenyl Head as Monoamine Oxidase-B Inhibitors by Rehuman, Nisha Abdul, Oh, Jong Min, Abdelgawad, Mohamed A, Beshr, Eman A M, Abourehab, Mohammed A S, Gambacorta, Nicola, Nicolotti, Orazio, Jat, Rakesh Kumar, Kim, Hoon, Mathew, Bijo

“…Two series of dimethoxy-halogenated chalcones (DM1−DM20) were synthesized and tested for their ability to inhibit monoamine oxidase (MAOs). Compound DM2…”
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