Search Results - "Abotsi, Wonder"
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Investigation of Herb-Drug Interactions between Xylopia aethiopica, Its Principal Constituent Xylopic Acid, and Antidepressants
Published in Advances in pharmacological and pharmaceutical sciences (25-05-2024)“…Introduction. Depression affects an estimated 350 million people worldwide and is implicated in up to 60% of suicides. Only about 60–70% of patients respond to…”
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Analgesic effects of an ethanol extract of the fruits of Xylopia aethiopica (Dunal) A. Rich (Annonaceae) and the major constituent, xylopic acid in murine models
Published in Journal of pharmacy & bioallied science (01-10-2012)“…Fruit extracts of Xylopia aethiopica are used traditionally in the management of pain disorders including rheumatism, headache, colic pain, and neuralgia…”
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Antinociceptive effects of a hydroethanolic stem bark extract of Burkea africana
Published in Heliyon (01-02-2022)“…Pain is a major symptom of many clinical disorders and its relief has long been a concern for individuals across the globe. There is therefore an unmet need to…”
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Antinociceptive effect of an ethanolic extract of the aerial parts of Hilleria latifolia (Lam.) H. Walt. (Phytolaccaceae)
Published in Journal of pharmacy & bioallied science (01-07-2011)“…Hilleria latifolia (Lam.) H. Walt. (Phytolaccaceae) is a perennial herb used in Ghanaian traditional medicine for the treatment of various painful conditions…”
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Anti-allodynic and Anti-hyperalgesic effects of an ethanolic extract and xylopic acid from the fruits of Xylopia aethiopica in murine models of neuropathic pain
Published in Pharmacognosy research (01-04-2014)“…Background: Fruit extracts of Xylopia aethiopica are used traditionally in the management of pain disorders including headache and neuralgia. An animal model…”
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Antiarthritic and antioxidant effects of the leaf extract of Ficus exasperata P. Beauv. (Moraceae)
Published in Pharmacognosy research (01-03-2010)“…Leaf extracts of Ficus exasperata P. Beauv. (Moraceae) are commonly used in Ghanaian traditional medicine for the treatment of several pathological states…”
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Analgesic effects of stem bark extracts of Trichilia monadelpha (Thonn.) JJ De Wilde
Published in Indian journal of pharmacology (01-11-2012)“…Various parts of Trichilia monadelpha (Thonn) JJ De Wilde (Fam. Meliaceae) are used in Ghanaian traditional medicine for the treatment of painful and…”
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Anticonvulsant Effects of a Leaf Extract of Ficus exasperata Vahl (Moraceae) in Mice
Published in International journal of pharmacology (01-04-2011)Get full text
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Involvement of catecholaminergic and nitric oxide–cGMP pathways in the antidepressant-like effects of hydroethanolic leaf extract of Morinda Longiflora G. Don in Mice
Published in Scientific African (01-09-2024)“…•Morinda Longiflora G. Don hydroethanolic leaf extract possesses antidepressant-like properties in animal models.•The antidepressant-like activity of M…”
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Ceiba pentandra (L.) Gaertn hydroethanolic leaf extract exhibits anticonvulsant properties in mouse models
Published in Phytomedicine Plus : International journal of phytotherapy and phytopharmacology (01-05-2022)“…Ceiba pentandra (L.) Gaertn. (Malvaceae) is a plant documented folklorically to be used in the management of epilepsy but with no scientific evidence to…”
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Synergistic antidepressant-like effect of xylopic acid co-administered with selected antidepressants
Published in IBRO neuroscience reports (01-06-2024)“…Xylopic acid (XA), a kaurene diterpene from the dried fruits of Xylopia aethiopica, has anxiolytic- and antidepressant-like activity in mice and zebrafish. We…”
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Anti-Arthritic Effect of the Hydroethanolic Root Extract of Psydrax subcordata in Rats
Published in Advances in pharmacological and pharmaceutical sciences (24-08-2022)“…Background. In Ghana, decoctions of various parts of Psydrax subcordata, Bridson (Rubiaceae) are employed in the management of inflammatory conditions…”
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The hydroethanolic root extract of Psydrax subcordata (DC.) Bridson exhibits antinociceptive and anti-inflammatory effects in animal models
Published in Scientific African (01-09-2022)“…•Psydrax subcordata (DC.) Bridson hydroethanolic root extract possesses antinociceptive and anti-inflammatory properties in animal models.•LD50 was estimated…”
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An evaluation of the anti-inflammatory, antipyretic and analgesic effects of hydroethanol leaf extract of Albizia zygia in animal models
Published in Pharmaceutical biology (01-01-2017)“…Context: The leaves of Albizia zygia (DC.) J.F. Macbr. (Leguminosae-Mimosoideae) are used in Ghanaian traditional medicine for the treatment of pain,…”
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Possible mechanisms involved in the anti-nociceptive effects of hydro-ethanolic leaf extract of Ziziphus abyssinica
Published in Pharmaceutical biology (2017)“…Context: Various parts of Ziziphus abyssinica Hochst ex. A. Rich (Rhamnaceae) have been used in Ghanaian and African traditional medicine as an analgesic…”
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Hydroethanolic Stem Bark Extract of Burkea africana Attenuates Vincristine-Induced Peripheral Neuropathy in Rats
Published in Advances in pharmacological and pharmaceutical sciences (2020)“…Context. The stem bark of the savanna tree Burkea africana (Hook) (family: Leguminosae) is used in the Ghanaian traditional medicine for the management of…”
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Anti-inflammatory activity of aqueous leaf extract of Phyllanthus muellerianus (Kuntze) Exell. and its major constituent, geraniin
Published in Journal of ethnopharmacology (01-07-2016)“…Phyllanthus muellerianus (Kuntze) Exell. which belongs to the Family Euphorbiaceae is a shrub widely distributed in West Africa. It is used traditionally to…”
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Anticonvulsant effect of the hydroethanolic leaf extract of Psydrax subcordata (DC.) Bridson in murine models
Published in Journal of ethnopharmacology (01-03-2018)“…Psydrax subcordata (DC.) Bridson is a tropical medicinal plant used traditionally for the management of epilepsy. However, there is little scientific evidence…”
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Regulation of Nrf2 and NF-κB activities may contribute to the anti-inflammatory mechanism of xylopic acid
Published in Inflammopharmacology (01-10-2022)“…Xylopic acid (XA) is a kaurene diterpene which naturally exists in African plants such as Xylopia aethiopica . It has been established to exhibit acute and…”
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Albizia zygia (DC.) J.F. Macbr. (Leguminosae-Mimosoideae) root extract exhibits anti-nociceptive and antipyretic activities in murine models
Published in Journal of ethnopharmacology (06-03-2017)“…The root extract of Albizia zygia (DC.) J.F. Macbr. (Leguminosae-Mimosoideae) is traditionally used in the management of pain and fever. However, little…”
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