Search Results - "Abolhassani , Hassan"

Current genetic landscape in common variable immune deficiency by Abolhassani, Hassan, Hammarström, Lennart, Cunningham-Rundles, Charlotte

“…Using whole-exome sequencing to examine the genetic causes of immune deficiency in 235 common variable immunodeficiency (CVID) patients seen in the United…”
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Ataxia‐telangiectasia: A review of clinical features and molecular pathology by Amirifar, Parisa, Ranjouri, Mohammad Reza, Yazdani, Reza, Abolhassani, Hassan, Aghamohammadi, Asghar

“…Ataxia‐telangiectasia (A‐T) is an autosomal recessive primary immunodeficiency (PID) disease that is caused by mutations in ataxia‐telangiectasia mutated (ATM)…”
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Specific Immune Response and Cytokine Production in CD70 Deficiency by Abolhassani, Hassan

“…Collective clinical and immunologic findings of defects in the CD27-CD70 axis indicate a primary immunodeficiency associated with terminal B-cell development…”
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Clinical implications of systematic phenotyping and exome sequencing in patients with primary antibody deficiency by Abolhassani, Hassan, Aghamohammadi, Asghar, Fang, Mingyan, Rezaei, Nima, Jiang, Chongyi, Liu, Xiao, Pan-Hammarström, Qiang, Hammarström, Lennart

“…The etiology of 80% of patients with primary antibody deficiency (PAD), the second most common type of human immune system disorder after human…”
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A hypomorphic recombination-activating gene 1 ( RAG1 ) mutation resulting in a phenotype resembling common variable immunodeficiency by Abolhassani, Hassan, MD, Wang, Ning, PhD, Aghamohammadi, Asghar, MD, PhD, Rezaei, Nima, MD, PhD, Lee, Yu Nee, PhD, Frugoni, Francesco, PhD, Notarangelo, Luigi D., MD, Pan-Hammarström, Qiang, MD, PhD, Hammarström, Lennart, MD, PhD

“…Background Recombination-activating gene 1 (RAG1) deficiency presents with a varied spectrum of combined immunodeficiency, ranging from a T− B− NK+ type of…”
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Impact of SARS-CoV-2 Pandemic on Patients with Primary Immunodeficiency by Delavari, Samaneh, Abolhassani, Hassan, Abolnezhadian, Farhad, Babaha, Fateme, Iranparast, Sara, Ahanchian, Hamid, Moazzen, Nasrin, Nabavi, Mohammad, Arshi, Saba, Fallahpour, Morteza, Bemanian, Mohammad Hassan, Shokri, Sima, Momen, Tooba, Sadeghi-Shabestari, Mahnaz, Molatefi, Rasol, Shirkani, Afshin, Vosughimotlagh, Ahmad, Safarirad, Molood, Sharifzadeh, Meisam, Pashangzadeh, Salar, Salami, Fereshte, Shirmast, Paniz, Rezaei, Arezou, Moeini Shad, Tannaz, Mohraz, Minoo, Rezaei, Nima, Hammarström, Lennart, Yazdani, Reza, Aghamohamamdi, Asghar

“…Although it is estimated that COVID-19 life-threatening conditions may be diagnosed in less than 1:1000 infected individuals below the age of 50, but the real…”
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Clinical, Immunological, and Genetic Features in Patients with Activated PI3Kδ Syndrome (APDS): a Systematic Review by Jamee, Mahnaz, Moniri, Shakiba, Zaki-Dizaji, Majid, Olbrich, Peter, Yazdani, Reza, Jadidi-Niaragh, Farhad, Aghamahdi, Fatemeh, Abolhassani, Hassan, Condliffe, Alison M., Aghamohammadi, Asghar, Azizi, Gholamreza

“…Activated phosphoinositide 3-kinase delta syndrome (APDS) is a novel primary immunodeficiency (PID) caused by heterozygous gain of function mutations in PI3Kδ…”
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B- and T-Cell Subset Abnormalities in Monogenic Common Variable Immunodeficiency by Fekrvand, Saba, Khanmohammadi, Shaghayegh, Abolhassani, Hassan, Yazdani, Reza

“…Common variable immunodeficiency (CVID) is a heterogeneous group of inborn errors of immunity characterized by reduced serum concentrations of different…”
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Hallmarks of Cancers: Primary Antibody Deficiency Versus Other Inborn Errors of Immunity by Abolhassani, Hassan, Wang, Yating, Hammarström, Lennart, Pan-Hammarström, Qiang

“…Inborn Errors of Immunity (IEI) comprise more than 450 inherited diseases, from which selected patients manifest a frequent and early incidence of…”
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Inherited IFNAR1 Deficiency in a Child with Both Critical COVID-19 Pneumonia and Multisystem Inflammatory Syndrome by Abolhassani, Hassan, Landegren, Nils, Bastard, Paul, Materna, Marie, Modaresi, Mohammadreza, Du, Likun, Aranda-Guillén, Maribel, Sardh, Fabian, Zuo, Fanglei, Zhang, Peng, Marcotte, Harold, Marr, Nico, Khan, Taushif, Ata, Manar, Al-Ali, Fatima, Pescarmona, Remi, Belot, Alexandre, Béziat, Vivien, Zhang, Qian, Casanova, Jean-Laurent, Kämpe, Olle, Zhang, Shen-Ying, Hammarström, Lennart, Pan-Hammarström, Qiang

“…Background Inborn errors of immunity (IEI) and autoantibodies to type I interferons (IFNs) underlie critical COVID-19 pneumonia in at least 15% of the…”
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Novel mutations in TNFRSF7 / CD27 : Clinical, immunologic, and genetic characterization of human CD27 deficiency by Alkhairy, Omar K., MD, Perez-Becker, Ruy, MD, Driessen, Gertjan J., MD, PhD, Abolhassani, Hassan, MD, van Montfrans, Joris, MD, PhD, Borte, Stephan, MD, Choo, Sharon, MD, Wang, Ning, PhD, Tesselaar, Kiki, PhD, Fang, Mingyan, PhD, Bienemann, Kirsten, MD, Boztug, Kaan, MD, Daneva, Ana, MSc, Mechinaud, Francoise, MD, Wiesel, Thomas, MD, Becker, Christian, MD, Dückers, Gregor, MD, Siepermann, Kathrin, MD, van Zelm, Menno C., PhD, Rezaei, Nima, MD, PhD, van der Burg, Mirjam, PhD, Aghamohammadi, Asghar, MD, PhD, Seidel, Markus G., MD, Niehues, Tim, MD, Hammarström, Lennart, MD, PhD

“…Background The clinical and immunologic features of CD27 deficiency remain obscure because only a few patients have been identified to date. Objective We…”
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RAC2 loss-of-function mutation in 2 siblings with characteristics of common variable immunodeficiency by Alkhairy, Omar K., MD, Rezaei, Nima, MD, PhD, Graham, Robert R., PhD, Abolhassani, Hassan, MD, Borte, Stephan, MD, Hultenby, Kjell, PhD, Wu, Chenglin, PhD, Aghamohammadi, Asghar, MD, PhD, Williams, David A., MD, Behrens, Timothy W., MD, Hammarström, Lennart, MD, PhD, Pan-Hammarström, Qiang, MD, PhD

“…The affected gene encodes RAC2, a hematopoietic-specific member of the Rho family of guanosine triphosphatases (Rho GTPase), which are crucial regulators of…”
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Primary Immunodeficiency Diseases and Bacillus Calmette-Guérin (BCG)-Vaccine–Derived Complications: A Systematic Review by Fekrvand, Saba, Yazdani, Reza, Olbrich, Peter, Gennery, Andrew, Rosenzweig, Sergio D., Condino-Neto, Antonio, Azizi, Gholamreza, Rafiemanesh, Hosein, Hassanpour, Gholamreza, Rezaei, Nima, Abolhassani, Hassan, Aghamohammadi, Asghar

“…Bacillus Calmette-Guérin (BCG) vaccine is a live attenuated bacterial vaccine derived from Mycobacterium bovis, which is mostly administered to neonates in…”
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X-Linked TLR7 Deficiency Underlies Critical COVID-19 Pneumonia in a Male Patient with Ataxia-Telangiectasia by Abolhassani, Hassan, Vosughimotlagh, Ahmad, Asano, Takaki, Landegren, Nils, Boisson, Bertrand, Delavari, Samaneh, Bastard, Paul, Aranda-Guillén, Maribel, Wang, Yating, Zuo, Fanglei, Sardh, Fabian, Marcotte, Harold, Du, Likun, Zhang, Shen-Ying, Zhang, Qian, Rezaei, Nima, Kämpe, Olle, Casanova, Jean-Laurent, Hammarström, Lennart, Pan-Hammarström, Qiang

“…Background Coronavirus disease 2019 (COVID-19) exhibits a wide spectrum of clinical manifestations, ranging from asymptomatic to critical conditions…”
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Variable Abnormalities in T and B Cell Subsets in Ataxia Telangiectasia by Moeini Shad, Tannaz, Yousefi, Bahman, Amirifar, Parisa, Delavari, Samaneh, Rae, William, Kokhaei, Parviz, Abolhassani, Hassan, Aghamohammadi, Asghar, Yazdani, Reza

“…Background Ataxia-telangiectasia (AT) is a rare genetic condition, caused by biallelic deleterious variants in the ATM gene, and has variable immunological…”
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Clinical, Immunological, and Genetic Features in 49 Patients With ZAP-70 Deficiency: A Systematic Review by Sharifinejad, Niusha, Jamee, Mahnaz, Zaki-Dizaji, Majid, Lo, Bernice, Shaghaghi, Mohammadreza, Mohammadi, Hamed, Jadidi-Niaragh, Farhad, Shaghaghi, Shiva, Yazdani, Reza, Abolhassani, Hassan, Aghamohammadi, Asghar, Azizi, Gholamreza

“…Zeta-Chain Associated Protein Kinase 70 kDa (ZAP-70) deficiency is a rare combined immunodeficiency (CID) caused by recessive homozygous/compound heterozygous…”
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Next Generation Sequencing Data Analysis in Primary Immunodeficiency Disorders – Future Directions by Fang, Mingyan, Abolhassani, Hassan, Lim, Che Kang, Zhang, Jianguo, Hammarström, Lennart

“…Primary immunodeficiency diseases (PIDs) comprise a group of highly heterogeneous immune system diseases and around 300 forms of PID have been described to…”
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Autoimmunity in common variable immunodeficiency: epidemiology, pathophysiology and management by Azizi, Gholamreza, Abolhassani, Hassan, Asgardoon, Mohammad Hosein, Alinia, Tina, Yazdani, Reza, Mohammadi, Javad, Rezaei, Nima, Ochs, Hans D, Aghamohammadi, Asghar

“…Common variable immunodeficiency (CVID) comprises a large heterogeneous group of patients with primary antibody deficiency. Areas covered: The affected…”
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From variant of uncertain significance to likely pathogenic in two siblings with atypical RAG2 Deficiency: a case report and review of the literature by Taghizadeh, Nima, Mohammadi, Soha, Abolhassani, Hassan, Shokri, Sima, Nabavi, Mohammad, Fallahpour, Morteza, Bemanian, Mohammad Hassan

“…Severe combined immunodeficiencies (SCIDs) are hereditary disorders characterized by impaired T and B cell function, resulting in significant immune system…”
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SARS-CoV-2 infection in patients with inborn errors of immunity due to DNA repair defects by Wang, Yating, Abolhassani, Hassan, Hammarström, Lennart, Pan-Hammarström, Qiang

“…Clinical information on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in patients with inborn errors of immunity (IEI) during the…”
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