Search Results - "Aboagye, Jeremy"
-
1
Tolerability and immunogenicity of an intranasally-administered adenovirus-vectored COVID-19 vaccine: An open-label partially-randomised ascending dose phase I trial
Published in EBioMedicine (01-11-2022)“…Intranasal vaccination may induce protective local and systemic immune responses against respiratory pathogens. A number of intranasal SARS-CoV-2 vaccine…”
Get full text
Journal Article -
2
Safety and immunogenicity of ChAdOx1 MERS vaccine candidate in healthy Middle Eastern adults (MERS002): an open-label, non-randomised, dose-escalation, phase 1b trial
Published in The Lancet. Microbe (01-01-2022)“…ChAdOx1-vectored vaccine candidates against several pathogens have been developed and tested in clinical trials and ChAdOx1 nCoV-19 has now been licensed for…”
Get full text
Journal Article -
3
Safety and immunogenicity of varied doses of R21/Matrix-M™ vaccine at three years follow-up: A phase 1b age de-escalation, dose-escalation trial in adults, children, and infants in Kilifi-Kenya
Published in Wellcome open research (2023)“…Falciparum malaria remains a global health problem. Two vaccines, based on the circumsporozoite antigen, are available. RTS, S/AS01 was recommended for use in…”
Get full text
Journal Article -
4
Safety and Immunogenicity of Adenovirus and Poxvirus Vectored Vaccines against a Mycobacterium Avium Complex Subspecies
Published in Vaccines (Basel) (16-03-2021)“…Heterologous prime-boost strategies are known to substantially increase immune responses in viral vectored vaccines. Here we report on safety and…”
Get full text
Journal Article -
5
Efficacy and immunogenicity of R21/Matrix-M vaccine against clinical malaria after 2 years' follow-up in children in Burkina Faso: a phase 1/2b randomised controlled trial
Published in The Lancet infectious diseases (01-12-2022)“…Malaria is a leading cause of morbidity and mortality worldwide. We previously reported the efficacy of the R21/Matrix-M malaria vaccine, which reached the…”
Get full text
Journal Article -
6
The public health impact and cost-effectiveness of the R21/Matrix-M malaria vaccine: a mathematical modelling study
Published in The Lancet infectious diseases (01-05-2024)“…The R21/Matrix-M vaccine has demonstrated high efficacy against Plasmodium falciparum clinical malaria in children in sub-Saharan Africa. Using trial data, we…”
Get full text
Journal Article -
7
Persistence of the immune response after two doses of ChAdOx1 nCov-19 (AZD1222): 1 year of follow-up of two randomized controlled trials
Published in Clinical and experimental immunology (24-03-2023)“…Abstract The trajectory of immune responses following the primary dose series determines the decline in vaccine effectiveness over time. Here we report on…”
Get full text
Journal Article -
8
Safety and immunogenicity of a simian-adenovirus-vectored rabies vaccine: an open-label, non-randomised, dose-escalation, first-in-human, single-centre, phase 1 clinical trial
Published in The Lancet. Microbe (01-09-2022)“…Rabies kills around 60 000 people each year. ChAdOx2 RabG, a simian adenovirus-vectored rabies vaccine candidate, might have potential to provide low-cost…”
Get full text
Journal Article