Search Results - "Abo, Kristine M."

SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response by Huang, Jessie, Hume, Adam J., Abo, Kristine M., Werder, Rhiannon B., Villacorta-Martin, Carlos, Alysandratos, Konstantinos-Dionysios, Beermann, Mary Lou, Simone-Roach, Chantelle, Lindstrom-Vautrin, Jonathan, Olejnik, Judith, Suder, Ellen L., Bullitt, Esther, Hinds, Anne, Sharma, Arjun, Bosmann, Markus, Wang, Ruobing, Hawkins, Finn, Burks, Eric J., Saeed, Mohsan, Wilson, Andrew A., Mühlberger, Elke, Kotton, Darrell N.

“…A hallmark of severe COVID-19 pneumonia is SARS-CoV-2 infection of the facultative progenitors of lung alveoli, the alveolar epithelial type 2 cells (AT2s)…”
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Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2 by Hekman, Ryan M., Hume, Adam J., Goel, Raghuveera Kumar, Abo, Kristine M., Huang, Jessie, Blum, Benjamin C., Werder, Rhiannon B., Suder, Ellen L., Paul, Indranil, Phanse, Sadhna, Youssef, Ahmed, Alysandratos, Konstantinos D., Padhorny, Dzmitry, Ojha, Sandeep, Mora-Martin, Alexandra, Kretov, Dmitry, Ash, Peter E.A., Verma, Mamta, Zhao, Jian, Patten, J.J., Villacorta-Martin, Carlos, Bolzan, Dante, Perea-Resa, Carlos, Bullitt, Esther, Hinds, Anne, Tilston-Lunel, Andrew, Varelas, Xaralabos, Farhangmehr, Shaghayegh, Braunschweig, Ulrich, Kwan, Julian H., McComb, Mark, Basu, Avik, Saeed, Mohsan, Perissi, Valentina, Burks, Eric J., Layne, Matthew D., Connor, John H., Davey, Robert, Cheng, Ji-Xin, Wolozin, Benjamin L., Blencowe, Benjamin J., Wuchty, Stefan, Lyons, Shawn M., Kozakov, Dima, Cifuentes, Daniel, Blower, Michael, Kotton, Darrell N., Wilson, Andrew A., Mühlberger, Elke, Emili, Andrew

“…Human transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causative pathogen of the COVID-19 pandemic, exerts a massive health and…”
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Intraoperative hypovolemia as a possible precipitating factor for pituitary apoplexy: a case report by Abo, Kristine M, Kane, Joseph, Druckenbrod, Rachel C, Mooney, Michael A, Rachlin, Jacob

“…Pituitary apoplexy is acute infarction with or without hemorrhage of the pituitary gland. It is a rare but potentially life-threatening emergency that most…”
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Air-liquid interface culture promotes maturation and allows environmental exposure of pluripotent stem cell-derived alveolar epithelium by Abo, Kristine M, Sainz de Aja, Julio, Lindstrom-Vautrin, Jonathan, Alysandratos, Konstantinos-Dionysios, Richards, Alexsia, Garcia-de-Alba, Carolina, Huang, Jessie, Hix, Olivia T, Werder, Rhiannon B, Bullitt, Esther, Hinds, Anne, Falconer, Isaac, Villacorta-Martin, Carlos, Jaenisch, Rudolf, Kim, Carla F, Kotton, Darrell N, Wilson, Andrew A

“…Type 2 alveolar epithelial cells (AT2s), facultative progenitor cells of the lung alveolus, play a vital role in the biology of the distal lung. In vitro model…”
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MicroRNAs as diagnostic markers for pancreatic ductal adenocarcinoma and its precursor, pancreatic intraepithelial neoplasm by Xue, Yue, Abou Tayoun, Ahmad N, Abo, Kristine M, Pipas, J. Marc, Gordon, Stuart R, Gardner, Timothy B, Barth, Richard J, Suriawinata, Arief A, Tsongalis, Gregory J

“…Since the discovery of small non-coding RNAs, the analysis of microRNA (miRNA) expression patterns in human cancer have provided new insights into cancer…”
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β2-Adrenoreceptor is a regulator of the α-synuclein gene driving risk of Parkinson’s disease by Mittal, Shuchi, Bjørnevik, Kjetil, Im, Doo Soon, Flierl, Adrian, Dong, Xianjun, Locascio, Joseph J., Abo, Kristine M., Long, Elizabeth, Jin, Ming, Xu, Bing, Xiang, Yang K., Rochet, Jean-Christophe, Engeland, Anders, Rizzu, Patrizia, Heutink, Peter, Bartels, Tim, Selkoe, Dennis J., Caldarone, Barbara J., Glicksman, Marcie A., Khurana, Vikram, Schüle, Birgitt, Park, David S., Riise, Trond, Scherzer, Clemens R.

“…Copy number mutations implicate excess production of α-synuclein as a possibly causative factor in Parkinson’s disease (PD). Using an unbiased screen targeting…”
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Pulmonary Cellular Toxicity in Alpha-1 Antitrypsin Deficiency by Abo, Kristine M., Merritt, Carly, Basil, Maria C., Lin, Susan M., Cantu, Edward, Morley, Michael P., Bawa, Pushpinder, Gallagher, Marissa, Byers, Derek E., Morrisey, Edward E., Wilson, Andrew A.

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Human airway lineages derived from pluripotent stem cells reveal the epithelial responses to SARS-CoV-2 infection by Wang, Ruobing, Hume, Adam J, Beermann, Mary Lou, Simone-Roach, Chantelle, Lindstrom-Vautrin, Jonathan, Le Suer, Jake, Huang, Jessie, Olejnik, Judith, Villacorta-Martin, Carlos, Bullitt, Esther, Hinds, Anne, Ghaedi, Mahboobe, Rollins, Stuart, Werder, Rhiannon B, Abo, Kristine M, Wilson, Andrew A, Mühlberger, Elke, Kotton, Darrell N, Hawkins, Finn J

“…There is an urgent need to understand how SARS-CoV-2 infects the airway epithelium and in a subset of individuals leads to severe illness or death. Induced…”
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Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2 by Hekman, Ryan M., Hume, Adam J., Goel, Raghuveera Kumar, Abo, Kristine M., Huang, Jessie, Blum, Benjamin C., Werder, Rhiannon B., Suder, Ellen L., Paul, Indranil, Phanse, Sadhna, Youssef, Ahmed, Alysandratos, Konstantinos D., Padhorny, Dzmitry, Ojha, Sandeep, Mora-Martin, Alexandra, Kretov, Dmitry, Ash, Peter E.A., Verma, Mamta, Zhao, Jian, Patten, J.J., Villacorta-Martin, Carlos, Bolzan, Dante, Perea-Resa, Carlos, Bullitt, Esther, Hinds, Anne, Tilston-Lunel, Andrew, Varelas, Xaralabos, Farhangmehr, Shaghayegh, Braunschweig, Ulrich, Kwan, Julian H., McComb, Mark, Basu, Avik, Saeed, Mohsan, Perissi, Valentina, Burks, Eric J., Layne, Matthew D., Connor, John H., Davey, Robert, Cheng, Ji-Xin, Wolozin, Benjamin L., Blencowe, Benjamin J., Wuchty, Stefan, Lyons, Shawn M., Kozakov, Dima, Cifuentes, Daniel, Blower, Michael, Kotton, Darrell N., Wilson, Andrew A., Mühlberger, Elke, Emili, Andrew

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Generating 3D Spheres and 2D Air-Liquid Interface Cultures of Human Induced Pluripotent Stem Cell-Derived Type 2 Alveolar Epithelial Cells by Werder, Rhiannon B, Huang, Jessie, Abo, Kristine M, Hix, Olivia T, Minakin, Kasey, Alysandratos, Konstantinos-Dionysios, Merritt, Carly, Berthiaume, Kayleigh, Alber, Andrea B, Burgess, Claire L, Kotton, Darrell N, Wilson, Andrew A

“…In the lung, the alveolar epithelium is a physical barrier from environmental stimuli and plays an essential role in homeostasis and disease. Type 2 alveolar…”
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CRISPR interference interrogation of COPD GWAS genes reveals the functional significance of desmoplakin in iPSC-derived alveolar epithelial cells by Werder, Rhiannon B, Liu, Tao, Abo, Kristine M, Lindstrom-Vautrin, Jonathan, Villacorta-Martin, Carlos, Huang, Jessie, Hinds, Anne, Boyer, Nathan, Bullitt, Esther, Liesa, Marc, Silverman, Edwin K, Kotton, Darrell N, Cho, Michael H, Zhou, Xiaobo, Wilson, Andrew A

“…Genome-wide association studies (GWAS) have identified dozens of loci associated with chronic obstructive pulmonary disease (COPD) susceptibility; however, the…”
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Maturation of Pluripotent Stem Cell-Derived Alveolar Type II Cells at Air-Liquid Interface and Response to Environmental Stimuli by Abo, Kristine M

“…Human pulmonary alveolar type II cells (AT2s) are facultative progenitors of the distal lung epithelium and secrete surfactant, a protein-lipid mixture that…”
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[beta]2-Adrenoreceptor is a regulator of the [alpha]-synuclein gene driving risk of Parkinson's disease by Mittal, Shuchi, Bjørnevik, Kjetil, Im, Doo Soon, Flierl, Adrian, Dong, Xianjun, Locascio, Joseph J, Abo, Kristine M, Long, Elizabeth, Jin, Ming, Xu, Bing, Xiang, Yang K, Rochet, Jean-Christophe, Engeland, Anders, Rizzu, Patrizia, Heutink, Peter, Bartels, Tim, Selkoe, Dennis J, Caldarone, Barbara J, Glicksman, Marcie A, Khurana, Vikram, Schüle, Birgitt, Park, David S, Riise, Trond, Scherzer, Clemens R

“…High expression of the α-synuclein gene (SNCA) is a risk factor for Parkinson's disease (PD), but certain drugs may mitigate this risk. Mittal et al. ran a…”
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