Search Results - "Abliz, Zeper"
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Spatially resolved metabolomics to discover tumor-associated metabolic alterations
Published in Proceedings of the National Academy of Sciences - PNAS (02-01-2019)“…Characterization of tumor metabolism with spatial information contributes to our understanding of complex cancer metabolic reprogramming, facilitating the…”
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A new water-soluble pillar[5]arene: synthesis and application in the preparation of gold nanoparticles
Published in Chemical communications (Cambridge, England) (01-01-2012)“…A new water-soluble pillar[5]arene containing ten imidazolium groups was prepared. It can be used as a stabilizer to fabricate gold nanoparticles smaller than…”
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3
Design of Bis-spiropyran Ligands as Dipolar Molecule Receptors and Application to in Vivo Glutathione Fluorescent Probes
Published in Journal of the American Chemical Society (20-01-2010)“…Despite considerable efforts toward the development of various sophisticated spiropyrans for metal ion sensing, less attention has been paid to organic…”
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4
Combination of Droplet Extraction and Pico-ESI-MS Allows the Identification of Metabolites from Single Cancer Cells
Published in Analytical chemistry (Washington) (21-08-2018)“…We have combined droplet extraction and a pulsed direct current electrospray ionization mass spectrometry method (Pico-ESI-MS) to obtain information-rich…”
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5
Rewiring of purine metabolism in response to acidosis stress in glioma stem cells
Published in Cell death & disease (15-03-2021)“…Glioma stem cells (GSCs) contribute to therapy resistance and poor outcomes for glioma patients. A significant feature of GSCs is their ability to grow in an…”
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Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases
Published in Nature communications (30-04-2019)“…Cardiovascular and metabolic disease (CMD) remains a main cause of premature death worldwide. Berberine (BBR), a lipid-lowering botanic compound with…”
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Identification of Diagnostic Metabolic Signatures in Thyroid Tumors Using Mass Spectrometry Imaging
Published in Molecules (Basel, Switzerland) (31-07-2023)“…"Gray zone" thyroid follicular tumors are difficult to diagnose, especially when distinguishing between benign follicular thyroid adenoma (FTA) and malignant…”
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Synthesis of a water-soluble pillar[9]arene and its pH-responsive binding to paraquat
Published in Chemical communications (Cambridge, England) (01-01-2014)“…A water-soluble pillar[9]arene was synthesized. Its pH-responsive host-guest binding to paraquat in water was studied…”
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Spatial-resolved metabolomics reveals tissue-specific metabolic reprogramming in diabetic nephropathy by using mass spectrometry imaging
Published in Acta pharmaceutica Sinica. B (01-11-2021)“…Detailed knowledge on tissue-specific metabolic reprogramming in diabetic nephropathy (DN) is vital for more accurate understanding the molecular pathological…”
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10
Mapping the Metabolic Characteristics and Perturbation of Adult Casper Zebrafish by Ambient Mass Spectrometry Imaging
Published in Metabolites (04-04-2024)“…, a type of transparent mutant-line zebrafish, was generated to overcome the opaque trunk of an adult zebrafish for tumor modeling to realize real-time…”
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Application of imaging mass spectrometry for the molecular diagnosis of human breast tumors
Published in Scientific reports (12-02-2016)“…Distinguishing breast invasive ductal carcinoma (IDC) and breast ductal carcinoma in situ (DCIS) is a key step in breast surgery, especially to determine…”
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12
Air Flow-Assisted Ionization Imaging Mass Spectrometry Method for Easy Whole-Body Molecular Imaging under Ambient Conditions
Published in Analytical chemistry (Washington) (05-03-2013)“…Whole-body molecular imaging is able to directly map spatial distribution of molecules and monitor its biotransformation in intact biological tissue sections…”
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In situ metabolomics in nephrotoxicity of aristolochic acids based on air flow-assisted desorption electrospray ionization mass spectrometry imaging
Published in Acta pharmaceutica Sinica. B (01-06-2020)“…Understanding of the nephrotoxicity induced by drug candidates is vital to drug discovery and development. Herein, an in situ metabolomics method based on air…”
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Global and Targeted Metabolomics of Esophageal Squamous Cell Carcinoma Discovers Potential Diagnostic and Therapeutic Biomarkers
Published in Molecular & cellular proteomics (01-05-2013)“…Diagnostic and therapeutic biomarkers useful for esophageal squamous cell carcinoma (ESCC) have the ability to increase the long term survival of cancer…”
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15
The impact of chronic environmental metal and benzene exposure on human urinary metabolome among Chinese children and the elderly population
Published in Ecotoxicology and environmental safety (01-03-2019)“…The health effects of metals and benzene exposure have been extensively investigated; however, information on the impact of chronic environmental metal and…”
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16
In situ biomarker discovery and label-free molecular histopathological diagnosis of lung cancer by ambient mass spectrometry imaging
Published in Scientific reports (25-09-2015)“…Sensitive and spatial exploration of the metabolism of tumors at the metabolome level is highly challenging. In this study, we developed an in situ…”
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Molecular Pathological Diagnosis of Thyroid Tumors Using Spatially Resolved Metabolomics
Published in Molecules (Basel, Switzerland) (18-02-2022)“…The pathological diagnosis of benign and malignant follicular thyroid tumors remains a major challenge using the current histopathological technique. To…”
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18
Liquid Chromatography–Tandem Mass Spectrometry-Based Plasma Metabonomics Delineate the Effect of Metabolites’ Stability on Reliability of Potential Biomarkers
Published in Analytical chemistry (Washington) (05-03-2013)“…Metabonomics is an important platform for investigating the metabolites of integrated living systems and their dynamic responses to changes caused by both…”
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In situ label-free visualization of tissue distributions of salidroside in multiple mouse organs by MALDI-MS imaging
Published in International journal of mass spectrometry (01-07-2020)“…Detailed knowledge on the spatiotemporal distribution of drugs or drug candidates in bio-tissues is of vital importance for the determination of their…”
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Combination of Injection Volume Calibration by Creatinine and MS Signals’ Normalization to Overcome Urine Variability in LC-MS-Based Metabolomics Studies
Published in Analytical chemistry (Washington) (20-08-2013)“…It is essential to choose one preprocessing method for liquid chromatography–mass spectrometry (LC-MS)-based metabolomics studies of urine samples in order to…”
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