Search Results - "Abler, Lisa"

A uropathogenic E. coli UTI89 model of prostatic inflammation and collagen accumulation for use in studying aberrant collagen production in the prostate by Ruetten, Hannah, Sandhu, Jaskiran, Mueller, Brett, Wang, Peiqing, Zhang, Helen L, Wegner, Kyle A, Cadena, Mark, Sandhu, Simran, L Abler, Lisa, Zhu, Jonathan, O'Driscoll, Chelsea A, Chelgren, Britta, Wang, Zunyi, Shen, Tian, Barasch, Jonathan, Bjorling, Dale E, Vezina, Chad M

“…Bacterial infection is one known etiology of prostatic inflammation. Prostatic inflammation is associated with prostatic collagen accumulation and both are…”
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Characterization of fibrillar collagens and extracellular matrix of glandular benign prostatic hyperplasia nodules by Bauman, Tyler M, Nicholson, Tristan M, Abler, Lisa L, Eliceiri, Kevin W, Huang, Wei, Vezina, Chad M, Ricke, William A

“…Recent studies have associated lower urinary tract symptoms (LUTS) in men with prostatic fibrosis, but a definitive link between collagen deposition and LUTS…”
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Links between lower urinary tract symptoms, intermittent hypoxia and diabetes: Causes or cures? by Abler, Lisa L., Vezina, Chad M.

“…•Lower urinary tract symptoms (LUTS) are a group of symptoms that affect urination.•Few therapies eliminate LUTS, meaning a lifetime of treatments for most…”
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Urethral luminal epithelia are castration‐insensitive cells of the proximal prostate by Joseph, Diya B., Henry, Gervaise H., Malewska, Alicia, Iqbal, Nida S., Ruetten, Hannah M., Turco, Anne E., Abler, Lisa L., Sandhu, Simran K., Cadena, Mark T., Malladi, Venkat S., Reese, Jeffrey C., Mauck, Ryan J., Gahan, Jeffrey C., Hutchinson, Ryan C., Roehrborn, Claus G., Baker, Linda A., Vezina, Chad M., Strand, Douglas W.

“…Background Castration‐insensitive epithelial progenitors capable of regenerating the prostate have been proposed to be concentrated in the proximal region…”
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Conditional gene inactivation reveals roles for Fgf10 and Fgfr2 in establishing a normal pattern of epithelial branching in the mouse lung by Abler, Lisa L., Mansour, Suzanne L., Sun, Xin

“…Fibroblast growth factor 10 (FGF10) signaling through FGF receptor 2 (FGFR2) is required for lung initiation. While studies indicate that Fgf10 and Fgfr2 are…”
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Void spot assay procedural optimization and software for rapid and objective quantification of rodent voiding function, including overlapping urine spots by Wegner, Kyle A, Abler, Lisa L, Oakes, Steven R, Mehta, Guneet S, Ritter, K Elaine, Hill, Warren G, Zwaans, Bernadette M, Lamb, Laura E, Wang, Zunyi, Bjorling, Dale E, Ricke, William A, Macoska, Jill, Marker, Paul C, Southard-Smith, E Michelle, Eliceiri, Kevin W, Vezina, Chad M

“…Mouse urinary behavior is quantifiable and is used to pinpoint mechanisms of voiding dysfunction and evaluate potential human therapies. Approaches to evaluate…”
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In vivo replacement of damaged bladder urothelium by Wolffian duct epithelial cells by Joseph, Diya B., Chandrashekar, Anoop S., Abler, Lisa L., Chu, Li-Fang, Thomson, James A., Mendelsohn, Cathy, Vezina, Chad M.

“…The bladder’s remarkable regenerative capacity had been thought to derive exclusively from its own progenitors. While examining consequences of DNA…”
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Androgen receptor DNA methylation regulates the timing and androgen sensitivity of mouse prostate ductal development by Keil, Kimberly P., Abler, Lisa L., Laporta, Jimena, Altmann, Helene M., Yang, Bing, Jarrard, David F., Hernandez, Laura L., Vezina, Chad M.

“…Androgen receptor (AR) signaling initiates mouse prostate development by stimulating prostate ductal bud formation and specifying bud patterns. Curiously,…”
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The influence of intermittent hypoxia, obesity, and diabetes on male genitourinary anatomy and voiding physiology by Abler, Lisa L, O'Driscoll, Chelsea A, Colopy, Sara A, Stietz, Kimberly P Keil, Wang, Peiqing, Wang, Zunyi, Hartmann, Faye, Crader-Smith, Stephanie M, Oellete, Jonathan N, Mehta, Vatsal, Oakes, Steven R, Grimes, Matthew D, Mitchell, Gordon S, Baan, Mieke, Gallagher, Shannon J, Davis, Dawn B, Kimple, Michelle E, Bjorling, Dale E, Watters, Jyoti J, Vezina, Chad M

“…We used male BTBR mice carrying the mutation, which are subject to severe and progressive obesity and diabetes beginning at 6 wk of age, to examine the…”
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Epithelial DNA methyltransferase-1 regulates cell survival, growth and maturation in developing prostatic buds by Joseph, Diya B., Chandrashekar, Anoop S., Abler, Lisa L., Chu, Li-Fang, Thomson, James A., Vezina, Chad M.

“…DNA methyltransferase 1 (DNMT1) is required for embryogenesis but roles in late forming organ systems including the prostate, which emerges from the urethral…”
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Atlas of Wnt and R‐spondin gene expression in the developing male mouse lower urogenital tract by Mehta, Vatsal, Abler, Lisa L., Keil, Kimberly P., Schmitz, Christopher T., Joshi, Pinak S., Vezina, Chad M.

“…Prostate development is influenced by β‐catenin signaling, but it is unclear which β‐catenin activators are involved, where they are synthesized, and whether…”
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Impact of a folic acid-enriched diet on urinary tract function in mice treated with testosterone and estradiol by Keil, Kimberly P, Abler, Lisa L, Altmann, Helene M, Wang, Zunyi, Wang, Peiqing, Ricke, William A, Bjorling, Dale E, Vezina, Chad M

“…Aging men are susceptible to developing lower urinary tract symptoms, but the underlying etiology is unknown and the influence of dietary and environmental…”
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Wnt Inhibitory Factor 1 (Wif1) Is Regulated by Androgens and Enhances Androgen-Dependent Prostate Development by Keil, Kimberly P, Mehta, Vatsal, Branam, Amanda M, Abler, Lisa L, Buresh-Stiemke, Rita A, Joshi, Pinak S, Schmitz, Christopher T, Marker, Paul C, Vezina, Chad M

“…Fetal prostate development from urogenital sinus (UGS) epithelium requires androgen receptor (AR) activation in UGS mesenchyme (UGM). Despite growing awareness…”
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A high‐resolution molecular atlas of the fetal mouse lower urogenital tract by Abler, Lisa L., Keil, Kimberly P., Mehta, Vatsal, Joshi, Pinak S., Schmitz, Christopher T., Vezina, Chad M.

“…Epithelial‐stromal interactions in the lower urogenital tract (LUT) are integral to prostatic and seminal vesicle development in males, vaginal and uterine…”
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Beta-catenin (CTNNB1) induces Bmp expression in urogenital sinus epithelium and participates in prostatic bud initiation and patterning by Mehta, Vatsal, Schmitz, Christopher T., Keil, Kimberly P., Joshi, Pinak S., Abler, Lisa L., Lin, Tien-Min, Taketo, Makoto M., Sun, Xin, Vezina, Chad M.

“…Fetal prostate development is initiated by androgens and patterned by androgen dependent and independent signals. How these signals integrate to control…”
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Influence of animal husbandry practices on void spot assay outcomes in C57BL/6J male mice by Keil, Kimberly P., Abler, Lisa L., Altmann, Helene M., Bushman, Wade, Marker, Paul C., Li, Lingjun, Ricke, William A., Bjorling, Dale E., Vezina, Chad M.

“…Aims Mice are increasingly being used as models to investigate aspects of urinary dysfunction that humans with lower urinary tract symptoms (LUTS) experience…”
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In Utero and Lactational TCDD Exposure Increases Susceptibility to Lower Urinary Tract Dysfunction in Adulthood by Ricke, William A, Lee, Calvin W, Clapper, Tyler R, Schneider, Andrew J, Moore, Robert W, Keil, Kimberly P, Abler, Lisa L, Wynder, Jalissa L, López Alvarado, Arnaldo, Beaubrun, Isaac, Vo, Jenny, Bauman, Tyler M, Ricke, Emily A, Peterson, Richard E, Vezina, Chad M

“…Benign prostatic hyperplasia, prostate cancer, and changes in the ratio of circulating testosterone and estradiol often occur concurrently in aging men and can…”
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DNA methylation of E-cadherin is a priming mechanism for prostate development by Keil, Kimberly P., Abler, Lisa L., Mehta, Vatsal, Altmann, Helene M., Laporta, Jimena, Plisch, Erin H., Suresh, M., Hernandez, Laura L., Vezina, Chad M.

“…In prostate and other epithelial cancers, E-cadherin (CDH1) is downregulated inappropriately by DNA methylation to promote an invasive phenotype. Though cancer…”
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Histone acetylation regulates prostate ductal morphogenesis through a bone morphogenetic protein–dependent mechanism by Keil, Kimberly P., Altmann, Helene M., Abler, Lisa L., Hernandez, Laura L., Vezina, Chad M.

“…Background: Epigenetic factors influence stem cell function and other developmental events but their role in prostate morphogenesis is not completely known. We…”
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Visualization and quantification of mouse prostate development by in situ hybridization by Keil, Kimberly P., Mehta, Vatsal, Abler, Lisa L., Joshi, Pinak S., Schmitz, Christopher T., Vezina, Chad M.

“…The purpose of this study was to validate a combined in situ hybridization (ISH)/immunohistochemistry (IHC) staining method for visualizing and quantifying…”
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