Search Results - "Abitbol, Julia M"

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  1. 1

    Lineage-tracing and translatomic analysis of damage-inducible mitotic cochlear progenitors identifies candidate genes regulating regeneration by Udagawa, Tomokatsu, Atkinson, Patrick J, Milon, Beatrice, Abitbol, Julia M, Song, Yang, Sperber, Michal, Huarcaya Najarro, Elvis, Scheibinger, Mirko, Elkon, Ran, Hertzano, Ronna, Cheng, Alan G

    Published in PLoS biology (01-11-2021)
    “…Cochlear supporting cells (SCs) are glia-like cells critical for hearing function. In the neonatal cochlea, the greater epithelial ridge (GER) is a mitotically…”
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    Journal Article
  2. 2

    Differential effects of pannexins on noise-induced hearing loss by Abitbol, Julia M, Kelly, John J, Barr, Kevin, Schormans, Ashley L, Laird, Dale W, Allman, Brian L

    Published in Biochemical journal (15-12-2016)
    “…Hearing loss, including noise-induced hearing loss, is highly prevalent and severely hinders an individual's quality of life, yet many of the mechanisms that…”
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    Journal Article
  3. 3

    Hair Cell Regeneration: From Animals to Humans by Choi, Sung-Won, Abitbol, Julia, Cheng, Alan

    “…Cochlear hair cells are critical in converting sound into electrical signals that are relayed via the spiral ganglion neurons to the central auditory pathway…”
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  4. 4

    Selection of viral capsids and promoters affects the efficacy of rescue of Tmprss3-deficient cochlea by Aaron, Ksenia A., Pekrun, Katja, Atkinson, Patrick J., Billings, Sara E., Abitbol, Julia M., Lee, Ina A., Eltawil, Yasmin, Chen, Yuan-Siao, Dong, Wuxing, Nelson, Rick F., Kay, Mark A., Cheng, Alan G.

    “…Adeno-associated virus (AAV)-mediated gene transfer has shown promise in rescuing mouse models of genetic hearing loss, but how viral capsid and promoter…”
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  5. 5

    GJB2 Mutations Linked to Hearing Loss Exhibit Differential Trafficking and Functional Defects as Revealed in Cochlear-Relevant Cells by Beach, Rianne, Abitbol, Julia M, Allman, Brian L, Esseltine, Jessica L, Shao, Qing, Laird, Dale W

    “…gene (that encodes Cx26) mutations are causal of hearing loss highlighting the importance of Cx26-based channel signaling amongst the supporting cells in the…”
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  6. 6

    The connexin 30 A88V mutant reduces cochlear gap junction expression and confers long-term protection against hearing loss by Kelly, John J, Abitbol, Julia M, Hulme, Stephanie, Press, Eric R, Laird, Dale W, Allman, Brian L

    Published in Journal of cell science (16-01-2019)
    “…Mutations in the genes that encode the gap junction proteins connexin 26 (Cx26, encoded by ) and Cx30 ( ) are the leading cause of hereditary hearing loss…”
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  7. 7

    Mice harbouring an oculodentodigital dysplasia-linked Cx43 G60S mutation have severe hearing loss by Abitbol, Julia M, Kelly, John J, Barr, Kevin J, Allman, Brian L, Laird, Dale W

    Published in Journal of cell science (01-05-2018)
    “…Given the importance of connexin43 (Cx43, encoded by ) function in the central nervous system and sensory organ processing, we proposed that it would also be…”
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