Search Results - "Abian, O"

On the link between conformational changes, ligand binding and heat capacity by Vega, S., Abian, O., Velazquez-Campoy, A.

“…Conformational changes coupled to ligand binding constitute the structural and energetics basis underlying cooperativity, allostery and, in general, protein…”
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False-positive fecal immunochemical test results in colorectal cancer screening and gastrointestinal drug use by Domper Arnal, M. J., García Mateo, S., Hermoso-Durán, S., Abad, D., Carrera-Lasfuentes, P., Velazquez-Campoy, A., Abian Franco, O., Lanas, A.

“…Purpose The study aimed to determine the influence of drug treatments (proton pump inhibitors [PPIs] combined with other drugs) on the false-positive (FP) rate…”
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Mechanism of FMN Binding to the Apoflavodoxin from Helicobacter pylori by Ayuso-Tejedor, S, Abián, O, Velázquez-Campoy, A, Sancho, J

“…Flavodoxins are bacterial electron transport proteins whose redox competence is due to the presence of a tightly but noncovalently bound FMN molecule. While…”
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Correction to: False-positive fecal immunochemical test results in colorectal cancer screening and gastrointestinal drug use by Arnal, M. J. Domper, Mateo, S. García, Hermoso-Durán, S., Abad, D., Carrera-Lasfuentes, P., Velazquez-Campoy, A., Abian Franco, O., Lanas, A.

“…A correction to this paper has been published: https://doi.org/10.1007/s00384-021-03947-1…”
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Thermal liquid biopsy as a new tool for lung cancer patients diagnostic: Pilot study by Rodrigo, A., Abian, O., Velazquez-Campoy, A., Callejo, A., Vega, S., Fernandez, A., Sánchez-Gracia, O., Iranzo Gomez, P., Cruellas, M., Quilez Bielsa, E., Isla, D.

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Targeting NUPR1 by ZZW-115, alone and in combination with genotoxic agents, is an efficient strategy for PDAC treatment by Santofimia-Castaño, P., Lan, W., Swayden, M., Xia, Y., Zhou, Z., Audebert, S., Camoin, L., Huang, C., Peng, L., Geli, V., Velazquez-Campoy, A., Abian, O., Lomberk, G., Urrutia, R., Rizzuti, B., Soubeyran, P., Neira, J., Iovanna, J.

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Protein-cation interactions: structural and thermodynamic aspects by Arias-Moreno, X, Abian, O, Vega, S, Sancho, J, Velazquez-Campoy, A

“…Cations are specifically recognized by numerous proteins. Cations may play a structural role, as cofactors stabilizing their binding partners, or a functional…”
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Preparation of artificial hyper-hydrophilic micro-environments (polymeric salts) surrounding enzyme molecules: New enzyme derivatives to be used in any reaction medium by Abian, O, Wilson, L, Mateo, C, Fernández-Lorente, G, Palomo, J.M, Fernández-Lafuente, R, Guisán, J.M, Re, D, Tam, A, Daminatti, M

“…Although enzymes usually undergo rapid inactivations in the presence of organic media, the mechanism of these inactivations is often quite simple. An…”
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Enantioselective Synthesis of Phenylacetamides in the Presence of High Organic Cosolvent Concentrations Catalyzed by Stabilized Penicillin G Acylase. Effect of the Acyl Donor by Abian, Olga, Mateo, César, Palomo, José M., Fernández-Lorente, Gloria, Guisán, José M., Fernández-Lafuente, Roberto

“…Immobilization of penicillin G acylase on glyoxyl agarose and its further hydrophilization by physicochemical modification with ionic polymers has made it…”
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1344PThermal liquid biopsy as a new tool for lung cancer patients diagnostic: Pilot study by Rodrigo, A, Abian, O, Velazquez-Campoy, A, Callejo, A, Vega, S, Fernandez, A, Sánchez-Gracia, O, Iranzo Gomez, P, Cruellas, M, Quilez Bielsa, E, Isla, D

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1424P - Thermal liquid biopsy as a valuable tool in lung cancer screening programs by Rodrigo, A., Vega, S., Ojeda Cabrera, J., Sanchez-Gracia, O., Callejo, A., Fernandez, A., Iranzo, P., Cruellas Lapena, M., Quilez Bielsa, E., Velazquez-Campoy, A., Abian, O., Isla, D.

“…Implementing screening programs for risk populations can reduce lung cancer mortality by detecting the disease at early stages, when surgical intervention or…”
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1424PThermal liquid biopsy as a valuable tool in lung cancer screening programs by Rodrigo, A, Vega, S, Ojeda Cabrera, J, Sanchez-Gracia, O, Callejo, A, Fernandez, A, Iranzo, P, Cruellas Lapena, M, Quilez Bielsa, E, Velazquez-Campoy, A, Abian, O, Isla, D

“…Abstract Background Implementing screening programs for risk populations can reduce lung cancer mortality by detecting the disease at early stages, when…”
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Thermal liquid biopsy as a valuable tool in lung cancer screening programs by Rodrigo, A., Vega, S., Ojeda Cabrera, J., Sanchez-Gracia, O., Callejo, A., Fernandez, A., Iranzo, P., Cruellas Lapena, M., Quilez Bielsa, E., Velazquez-Campoy, A., Abian, O., Isla, D.

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Preparation of artificial hyper-hydrophilic micro-environments (polymeric salts) surrounding enzyme molecules by Abian, O, Wilson, L, Mateo, C, Fernández-Lorente, G, Palomo, J.M, Fernández-Lafuente, R, Guisán, J.M, Re, D, Tam, A, Daminatti, M

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Some special features of glyoxyl supports to immobilize proteins by Mateo, Cesar, Abian, Olga, Bernedo, Marieta, Cuenca, Emma, Fuentes, Manuel, Fernandez-Lorente, Gloria, Palomo, Jose M., Grazu, Valeria, Pessela, Benevides C.C., Giacomini, Cecilia, Irazoqui, Gabriela, Villarino, Andrea, Ovsejevi, Karen, Batista-Viera, Francisco, Fernandez-Lafuente, Roberto, Guisán, Jose M.

“…This paper described that glyoxyl activated supports are only able to quantitatively immobilize proteins at alkaline pH values and using highly activated…”
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Multifunctional Epoxy Supports:  A New Tool To Improve the Covalent Immobilization of Proteins. The Promotion of Physical Adsorptions of Proteins on the Supports before Their Covalent Linkage by Mateo, Cesar, Fernández-Lorente, Gloria, Abian, Olga, Fernández-Lafuente, Roberto, Guisán, Jose M

“…Multifunctional supports containing epoxy groups are here proposed as a second generation of activated supports for covalent immobilization of enzymes…”
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Rescuing compound bioactivity in a secondary cell-based screening by usingγ-cyclodextrin asa molecular carrier by Claveria-Gimeno R, Vega S, Grazu V, de la Fuente JM, Lanas A, Velazquez-Campoy A, Abian O

“…Rafael Claveria-Gimeno,1-3 Sonia Vega,3 Valeria Grazu,4 Jesús M de la Fuente,4-6 Angel Lanas,2,8-10 Adrian Velazquez-Campoy,2,3,7 Olga Abian1-3,8 1Instituto…”
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Increase in conformational stability of enzymes immobilized on epoxy-activated supports by favoring additional multipoint covalent attachment by Mateo, Cesar, Abian, Olga, Fernandez–Lafuente, Roberto, Guisan, Jose M.

“…Epoxy supports (Eupergit C) may be very suitable to achieve the multipoint covalent attachment of proteins and enzymes, therefore, to stabilize their…”
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Epoxy Sepabeads: A Novel Epoxy Support for Stabilization of Industrial Enzymes via Very Intense Multipoint Covalent Attachment by Mateo, Cesar, Abian, Olga, Fernández-Lorente, Gloria, Pedroche, Justo, Fernández-Lafuente, Roberto, Guisan, Jose M.

“…Sepabeads‐EP (a new epoxy support) has been utilized to immobilize‐stabilize the enzyme penicillin G acylase (PGA) via multipoint covalent attachment. These…”
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Epoxy-Amino Groups:  A New Tool for Improved Immobilization of Proteins by the Epoxy Method by Mateo, Cesar, Torres, Rodrigo, Fernández-Lorente, Gloria, Ortiz, Claudia, Fuentes, Manuel, Hidalgo, Aurelio, López-Gallego, Fernando, Abian, Olga, Palomo, Jose M., Betancor, Lorena, Pessela, Benevides C. C., Guisan, José M., Fernández-Lafuente, Roberto

“…The properties of a new commercially available amino-epoxy support (amino-epoxy-Sepabeads) for immobilizing enzymes have been compared to those of conventional…”
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