Search Results - "Abeza, Claire"
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Author Correction: The HSP90/R2TP assembly chaperone promotes cell proliferation in the intestinal epithelium
Published in Nature communications (19-10-2022)Get full text
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The HSP90/R2TP assembly chaperone promotes cell proliferation in the intestinal epithelium
Published in Nature communications (10-08-2021)“…The R2TP chaperone cooperates with HSP90 to integrate newly synthesized proteins into multi-subunit complexes, yet its role in tissue homeostasis is unknown…”
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Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones
Published in The Journal of cell biology (05-06-2017)“…Splicing is catalyzed by the spliceosome, a complex of five major small nuclear ribonucleoprotein particles (snRNPs). The pre-mRNA splicing factor PRPF8 is a…”
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The HSP90/R2TP Quaternary Chaperone Scaffolds Assembly of the TSC Complex
Published in Journal of molecular biology (01-12-2024)“…[Display omitted] •TSC1 directly interacts with the N-terminal binding pocket of PIH1D1 in a phosphorylation independent manner.•Inhibition of R2TP leads to a…”
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Inhibition of Proteasome Activity Induces Formation of Alternative Proteasome Complexes
Published in The Journal of biological chemistry (17-06-2016)“…The proteasome is an intracellular protease complex consisting of the 20S catalytic core and its associated regulators, including the 19S complex, PA28αβ,…”
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The RPAP3-Cterminal domain identifies R2TP-like quaternary chaperones
Published in Nature communications (29-05-2018)“…R2TP is an HSP90 co-chaperone that assembles important macro-molecular machineries. It is composed of an RPAP3-PIH1D1 heterodimer, which binds the two…”
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