Search Results - "Abeyweera, Thushara P"
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Inhibitory signaling blocks activating receptor clustering and induces cytoskeletal retraction in natural killer cells
Published in The Journal of cell biology (21-02-2011)“…Natural killer (NK) lymphocytes use a variety of activating receptors to recognize and kill infected or tumorigenic cells during an innate immune response. To…”
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2
Nanoelectrochemistry of mammalian cells
Published in Proceedings of the National Academy of Sciences - PNAS (15-01-2008)“…There is a significant current interest in development of new techniques for direct characterization of the intracellular redox state and high-resolution…”
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3
Building tolerance by dismantling synapses: inhibitory receptor signaling in natural killer cells
Published in Immunological reviews (01-01-2013)“…Summary Cell surface receptors bearing immunotyrosine‐based inhibitory motifs (ITIMs) maintain natural killer (NK) cell tolerance to normal host tissues. These…”
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Inhibitory receptor signaling destabilizes immunological synapse formation in primary NK cells
Published in Frontiers in immunology (01-01-2013)“…Upon engagement of their cognate class I major histocompatibility complex ligands, receptors containing immunotyrosine-based inhibitory motifs (ITIMs)…”
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Phosphorylation of α6-Tubulin by Protein Kinase Cα Activates Motility of Human Breast Cells
Published in The Journal of biological chemistry (26-06-2009)“…Engineered overexpression of protein kinase Cα (PKCα) was previously shown to endow nonmotile MCF-10A human breast cells with aggressive motility. A traceable…”
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6
Analysis of Substrates of Protein Kinase C Isoforms in Human Breast Cells by the Traceable Kinase Method
Published in Biochemistry (Easton) (11-09-2012)“…A previous report [Abeyweera, T. P., and Rotenberg, S. A. (2007) Biochemistry 46, 2364–2370] described the application of the traceable kinase method in…”
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Inhibitory signaling blocks activating receptor clustering and induces cytoskeletal retraction in natural killer cells
Published in The Journal of experimental medicine (14-03-2011)Get full text
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8
Protein kinase C-θ clustering at immunological synapses amplifies effector responses in NK cells
Published in The Journal of immunology (1950) (15-11-2012)“…In lymphocytes, stimulation of cell surface activating receptors induces the formation of protein microclusters at the plasma membrane that contain the…”
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9
Conformationally Constrained Analogues of Diacylglycerol. 29. Cells Sort Diacylglycerol-Lactone Chemical Zip Codes to Produce Diverse and Selective Biological Activities
Published in Journal of medicinal chemistry (11-09-2008)“…Diacylglycerol-lactone (DAG-lactone) libraries generated by a solid-phase approach using IRORI technology produced a variety of unique biological activities…”
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10
Design and Characterization of a Traceable Protein Kinase Cα
Published in Biochemistry (Easton) (06-03-2007)“…Protein kinase Cα (PKCα) is a critical component of pathways that govern cancer-related phenotypes such as invasion and proliferation. Proteins that serve as…”
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11
Building tolerance by dismantling synapses: inhibitory receptor signaling in natural killer cells: Cell:Cell Contacts
Published in Immunological reviews (2013)Get full text
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12
Protein Kinase C-[thetas] Clustering at Immunological Synapses Amplifies Effector Responses in NK Cells
Published in The Journal of immunology (1950) (15-11-2012)“…In lymphocytes, stimulation of cell surface activating receptors induces the formation of protein microclusters at the plasma membrane that contain the…”
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Journal Article -
13
Phosphorylation of α6-Tubulin by Protein Kinase Cα Activates Motility of Human Breast Cells
Published in The Journal of biological chemistry (26-06-2009)“…Engineered overexpression of protein kinase Cα (PKCα) was previously shown to endow nonmotile MCF-10A human breast cells with aggressive motility. A…”
Get full text
Journal Article -
14
Phosphorylation of alpha6-tubulin by protein kinase Calpha activates motility of human breast cells
Published in The Journal of biological chemistry (26-06-2009)“…Engineered overexpression of protein kinase Calpha (PKCalpha) was previously shown to endow nonmotile MCF-10A human breast cells with aggressive motility. A…”
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Journal Article -
15
Design and characterization of a traceable protein kinase Calpha
Published in Biochemistry (Easton) (06-03-2007)“…Protein kinase Calpha (PKCalpha) is a critical component of pathways that govern cancer-related phenotypes such as invasion and proliferation. Proteins that…”
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