Search Results - "Abernathy, Morgan E."

mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants by Wang, Zijun, Schmidt, Fabian, Weisblum, Yiska, Muecksch, Frauke, Barnes, Christopher O., Finkin, Shlomo, Schaefer-Babajew, Dennis, Cipolla, Melissa, Gaebler, Christian, Lieberman, Jenna A., Oliveira, Thiago Y., Yang, Zhi, Abernathy, Morgan E., Huey-Tubman, Kathryn E., Hurley, Arlene, Turroja, Martina, West, Kamille A., Gordon, Kristie, Millard, Katrina G., Ramos, Victor, Da Silva, Justin, Xu, Jianliang, Colbert, Robert A., Patel, Roshni, Dizon, Juan, Unson-O’Brien, Cecille, Shimeliovich, Irina, Gazumyan, Anna, Caskey, Marina, Bjorkman, Pamela J., Casellas, Rafael, Hatziioannou, Theodora, Bieniasz, Paul D., Nussenzweig, Michel C.

“…Here we report on the antibody and memory B cell responses of a cohort of 20 volunteers who received the Moderna (mRNA-1273) or Pfizer–BioNTech (BNT162b2)…”
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SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies by Barnes, Christopher O., Jette, Claudia A., Abernathy, Morgan E., Dam, Kim-Marie A., Esswein, Shannon R., Gristick, Harry B., Malyutin, Andrey G., Sharaf, Naima G., Huey-Tubman, Kathryn E., Lee, Yu E., Robbiani, Davide F., Nussenzweig, Michel C., West, Anthony P., Bjorkman, Pamela J.

“…The coronavirus disease 2019 (COVID-19) pandemic presents an urgent health crisis. Human neutralizing antibodies that target the host ACE2 receptor-binding…”
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Histidine-Directed Arylation/Alkenylation of Backbone N–H Bonds Mediated by Copper(II) by Ohata, Jun, Minus, Matthew B, Abernathy, Morgan E, Ball, Zachary T

“…Chemical modification of proteins and peptides represents a challenge of reaction design as well as an important biological tool. In contrast to side-chain…”
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Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques by Escolano, Amelia, Gristick, Harry B., Abernathy, Morgan E., Merkenschlager, Julia, Gautam, Rajeev, Oliveira, Thiago Y., Pai, Joy, West, Anthony P., Barnes, Christopher O., Cohen, Alexander A., Wang, Haoqing, Golijanin, Jovana, Yost, Daniel, Keeffe, Jennifer R., Wang, Zijun, Zhao, Peng, Yao, Kai-Hui, Bauer, Jens, Nogueira, Lilian, Gao, Han, Voll, Alisa V., Montefiori, David C., Seaman, Michael S., Gazumyan, Anna, Silva, Murillo, McGuire, Andrew T., Stamatatos, Leonidas, Irvine, Darrell J., Wells, Lance, Martin, Malcolm A., Bjorkman, Pamela J., Nussenzweig, Michel C.

“…Broadly neutralizing monoclonal antibodies protect against infection with HIV-1 in animal models, suggesting that a vaccine that elicits these antibodies would…”
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Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody by Schommers, Philipp, Gruell, Henning, Abernathy, Morgan E., Tran, My-Kim, Dingens, Adam S., Gristick, Harry B., Barnes, Christopher O., Schoofs, Till, Schlotz, Maike, Vanshylla, Kanika, Kreer, Christoph, Weiland, Daniela, Holtick, Udo, Scheid, Christof, Valter, Markus M., van Gils, Marit J., Sanders, Rogier W., Vehreschild, Jörg J., Cornely, Oliver A., Lehmann, Clara, Fätkenheuer, Gerd, Seaman, Michael S., Bloom, Jesse D., Bjorkman, Pamela J., Klein, Florian

“…Broadly neutralizing antibodies (bNAbs) represent a promising approach to prevent and treat HIV-1 infection. However, viral escape through mutation of the…”
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How Antibodies Recognize Pathogenic Viruses: Structural Correlates of Antibody Neutralization of HIV-1, SARS-CoV-2, and Zika by Abernathy, Morgan E, Dam, Kim-Marie A, Esswein, Shannon R, Jette, Claudia A, Bjorkman, Pamela J

“…The H1N1 pandemic of 2009-2010, MERS epidemic of 2012, Ebola epidemics of 2013-2016 and 2018-2020, Zika epidemic of 2015-2016, and COVID-19 pandemic of…”
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Antibody elicited by HIV-1 immunogen vaccination in macaques displaces Env fusion peptide and destroys a neutralizing epitope by Abernathy, Morgan E., Gristick, Harry B., Vielmetter, Jost, Keeffe, Jennifer R., Gnanapragasam, Priyanthi N. P., Lee, Yu E., Escolano, Amelia, Gautam, Rajeev, Seaman, Michael S., Martin, Malcolm A., Nussenzweig, Michel C., Bjorkman, Pamela J.

“…HIV-1 vaccine design aims to develop an immunogen that elicits broadly neutralizing antibodies against a desired epitope, while eliminating responses to…”
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Sequential immunization of macaques elicits heterologous neutralizing antibodies targeting the V3-glycan patch of HIV-1 Env by Escolano, Amelia, Gristick, Harry B, Gautam, Rajeev, DeLaitsch, Andrew T, Abernathy, Morgan E, Yang, Zhi, Wang, Haoqing, Hoffmann, Magnus A G, Nishimura, Yoshiaki, Wang, Zijun, Koranda, Nicholas, Kakutani, Leesa M, Gao, Han, Gnanapragasam, Priyanthi N P, Raina, Henna, Gazumyan, Ana, Cipolla, Melissa, Oliveira, Thiago Y, Ramos, Victor, Irvine, Darrell J, Silva, Murillo, West, Jr, Anthony P, Keeffe, Jennifer R, Barnes, Christopher O, Seaman, Michael S, Nussenzweig, Michel C, Martin, Malcolm A, Bjorkman, Pamela J

“…Broadly neutralizing antibodies (bNAbs) against HIV-1 develop after prolonged virus and antibody coevolution. Previous studies showed that sequential…”
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Author Correction: SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies by Barnes, Christopher O., Jette, Claudia A., Abernathy, Morgan E., Dam, Kim-Marie A., Esswein, Shannon R., Gristick, Harry B., Malyutin, Andrey G., Sharaf, Naima G., Huey-Tubman, Kathryn E., Lee, Yu E., Robbiani, Davide F., Nussenzweig, Michel C., West, Anthony P., Bjorkman, Pamela J.

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Human neutralizing antibodies to cold linear epitopes and subdomain 1 of the SARS-CoV-2 spike glycoprotein by Bianchini, Filippo, Crivelli, Virginia, Abernathy, Morgan E, Guerra, Concetta, Palus, Martin, Muri, Jonathan, Marcotte, Harold, Piralla, Antonio, Pedotti, Mattia, De Gasparo, Raoul, Simonelli, Luca, Matkovic, Milos, Toscano, Chiara, Biggiogero, Maira, Calvaruso, Veronica, Svoboda, Pavel, Cervantes Rincón, Tomás, Fava, Tommaso, Podešvová, Lucie, Shanbhag, Akanksha A, Celoria, Andrea, Sgrignani, Jacopo, Stefanik, Michal, Hönig, Vaclav, Pranclova, Veronika, Michalcikova, Tereza, Prochazka, Jan, Guerrini, Giuditta, Mehn, Dora, Ciabattini, Annalisa, Abolhassani, Hassan, Jarrossay, David, Uguccioni, Mariagrazia, Medaglini, Donata, Pan-Hammarström, Qiang, Calzolai, Luigi, Fernandez, Daniel, Baldanti, Fausto, Franzetti-Pellanda, Alessandra, Garzoni, Christian, Sedlacek, Radislav, Ruzek, Daniel, Varani, Luca, Cavalli, Andrea, Barnes, Christopher O, Robbiani, Davide F

“…Emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants diminishes the efficacy of vaccines and antiviral monoclonal antibodies…”
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Pan-sarbecovirus prophylaxis with human anti-ACE2 monoclonal antibodies by Zhang, Fengwen, Jenkins, Jesse, de Carvalho, Renan V. H., Nakandakari-Higa, Sandra, Chen, Teresia, Abernathy, Morgan E., Baharani, Viren A., Nyakatura, Elisabeth K., Andrew, David, Lebedeva, Irina V., Lorenz, Ivo C., Hoffmann, H.-Heinrich, Rice, Charles M., Victora, Gabriel D., Barnes, Christopher O., Hatziioannou, Theodora, Bieniasz, Paul D.

“…Human monoclonal antibodies (mAbs) that target the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein have been isolated from…”
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CD4 binding site immunogens elicit heterologous anti-HIV-1 neutralizing antibodies in transgenic and wild-type animals by Gristick, Harry B, Hartweger, Harald, Loewe, Maximilian, van Schooten, Jelle, Ramos, Victor, Oliveira, Thiago Y, Nishimura, Yoshiaki, Koranda, Nicholas S, Wall, Abigail, Yao, Kai-Hui, Poston, Daniel, Gazumyan, Anna, Wiatr, Marie, Horning, Marcel, Keeffe, Jennifer R, Hoffmann, Magnus A G, Yang, Zhi, Abernathy, Morgan E, Dam, Kim-Marie A, Gao, Han, Gnanapragasam, Priyanthi N P, Kakutani, Leesa M, Pavlovitch-Bedzyk, Ana Jimena, Seaman, Michael S, Howarth, Mark, McGuire, Andrew T, Stamatatos, Leonidas, Martin, Malcolm A, West, Jr, Anthony P, Nussenzweig, Michel C, Bjorkman, Pamela J

“…Passive transfer of broadly neutralizing anti-HIV-1 antibodies (bNAbs) protects against infection, and therefore, eliciting bNAbs by vaccination is a major…”
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Immunization expands HIV-1 V3-glycan specific B-cells in mice and macaques by Escolano, Amelia, Gristick, Harry B., Abernathy, Morgan E., Merkenschlager, Julia, Gautam, Rajeev, Oliveira, Thiago Y., Pai, Joy, West, Anthony P., Barnes, Christopher O., Cohen, Alexander A., Wang, Haoqing, Golijanin, Jovana, Yost, Daniel, Keeffe, Jennifer R., Wang, Zijun, Zhao, Peng, Yao, Kai-Hui, Bauer, Jens, Nogueira, Lilian, Gao, Han, Voll, Alisa V., Montefiori, David C., Seaman, Michael S., Gazumyan, Anna, Silva, Murillo, McGuire, Andrew T., Stamatatos, Leonidas, Irvine, Darrell J., Wells, Lance, Martin, Malcolm A., Bjorkman, Pamela J., Nussenzweig, Michel C.

“…Broadly neutralizing monoclonal antibodies protect against HIV-1 infection in animal models, suggesting that a vaccine that elicits them in humans would be…”
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