Search Results - "Aberle, Tim"

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    Sox10 Activity and the Timing of Schwann Cell Differentiation Are Controlled by a Tle4-Dependent Negative Feedback Loop by Aberle, Tim, Walter, Anna, Piefke, Sandra, Hillgärtner, Simone, Wüst, Hannah M, Wegner, Michael, Küspert, Melanie

    “…The HMG-domain containing transcription factor Sox10 plays a crucial role in regulating Schwann cell survival and differentiation and is expressed throughout…”
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    Journal Article
  3. 3

    Voltage-Gated Ion Channels Are Transcriptional Targets of Sox10 during Oligodendrocyte Development by Peters, Christian, Aberle, Tim, Sock, Elisabeth, Brunner, Jessica, Küspert, Melanie, Hillgärtner, Simone, Wüst, Hannah M, Wegner, Michael

    Published in Cells (Basel, Switzerland) (07-07-2024)
    “…The transcription factor Sox10 is an important determinant of oligodendroglial identity and influences oligodendroglial development and characteristics at…”
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    Journal Article
  4. 4

    Transcription factor Olig2 is a major downstream effector of histone demethylase Phf8 during oligodendroglial development by Kremp, Marco, Aberle, Tim, Sock, Elisabeth, Bohl, Bettina, Hillgärtner, Simone, Winkler, Jürgen, Wegner, Michael

    Published in Glia (01-08-2024)
    “…The plant homeodomain finger protein Phf8 is a histone demethylase implicated by mutation in mice and humans in neural crest defects and neurodevelopmental…”
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    Journal Article
  5. 5

    Transcription factor Zfp276 drives oligodendroglial differentiation and myelination by switching off the progenitor cell program by Aberle, Tim, Piefke, Sandra, Hillgärtner, Simone, Tamm, Ernst R, Wegner, Michael, Küspert, Melanie

    Published in Nucleic acids research (28-02-2022)
    “…Abstract In oligodendrocytes of the vertebrate central nervous system a complex network of transcriptional regulators is required to ensure correct and timely…”
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    Journal Article
  6. 6

    Zinc Finger Protein Zfp276 Is a Novel Transcriptional Regulator Driving Oligodendroglial Differentiation by Inhibition of Immaturity Factors by Aberle, Tim

    Published 01-01-2022
    “…Fast saltatory nerve conduction relies on myelin sheaths which isolate axons and are produced by myelinating oligodendrocytes in the central nervous system…”
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    Dissertation
  7. 7

    The myelination‐associated G protein‐coupled receptor 37 is regulated by Zfp488, Nkx2.2, and Sox10 during oligodendrocyte differentiation by Schmidt, Antonia L., Kremp, Marco, Aratake, Takaaki, Cui, Siying, Lin, Yifeng, Zhong, Xiaowen, Lu, Q. Richard, Zhang, Chengfu, Qiu, Mengsheng, Aberle, Tim, Wegner, Michael

    Published in Glia (01-07-2024)
    “…Oligodendrocyte differentiation and myelination in the central nervous system are controlled and coordinated by a complex gene regulatory network that contains…”
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    Journal Article