Search Results - "Abera, B"
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1
Protein kinase C and cancer: what we know and what we do not
Published in Oncogene (06-11-2014)“…Since their discovery in the late 1970s, protein kinase C (PKC) isozymes represent one of the most extensively studied signaling kinases. PKCs signal through…”
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2
Kisspeptin regulation of genes involved in cell invasion and angiogenesis in first trimester human trophoblast cells
Published in PloS one (12-06-2014)“…The precise regulation of extravillous trophoblast invasion of the uterine wall is a key process in successful pregnancies. Kisspeptin (KP) has been shown to…”
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3
Antimicrobial susceptibility patterns of E. coli from clinical sources in northeast Ethiopia
Published in African health sciences (01-08-2011)“…Background: Escherichia coli is the leading cause of urinary tract, ear, wound and other infections in humans. Increasing rates of antimicrobial resistance…”
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4
Epidemiology of pre-cancerous cervical lesion and risk factors among adult women in Tigray, Ethiopia
Published in PloS one (06-01-2023)“…Cervical cancer is a preventable disease if treated early, but remains the second leading cause of cancer-related mortality among women in low and…”
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5
Neonatal presentation of a patient with Liddle syndrome, South Africa
Published in African journal of laboratory medicine (2023)“…Introduction: Liddle syndrome is an autosomal dominantly inherited disorder usually arising from single mutations of the genes that encode for the alpha, beta…”
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6
Magnitude of Neonatal Jaundice and Its Associated Factor in Neonatal Intensive Care Units of Mekelle City Public Hospitals, Northern Ethiopia
Published in International journal of pediatrics (01-01-2019)“…Background. Jaundice in the neonate is one of the most common clinical problems. Globally, every year about 1.1 million babies develop it and the vast majority…”
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7
Bacteriological and physico-chemical quality of drinking water sources in a rural community of Ethiopia
Published in African health sciences (2013)“…Accesses to safe water is a universal need however, many of the world's population lack access to adequate and safe water. Consumption of water contaminated…”
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8
Antibiogram of nosocomial urinary tract infections in Felege Hiwot referral hospital, Ethiopia
Published in African health sciences (01-06-2012)“…Background: Nosocomial infections increase the cost of medical care, extend hospital stay and reflect on the morbidity and mortality of the admitted patients…”
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9
Prevalence and Etiology of Subclinical Mastitis in Small Ruminants of Tigray Regional State, North Ethiopia
Published in Veterinary World (01-02-2012)“…A study was conducted at Kafta Humera and Tanqua Abergelle Districts from April to June, 2011 to assess the prevalence of subclinical mastitis in lactating…”
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10
Protein kinase Cα mediates erlotinib resistance in lung cancer cells
Published in Molecular pharmacology (01-05-2015)“…Overexpression and mutational activation of the epidermal growth factor receptor (EGFR) plays an important role in the pathogenesis of non-small cell lung…”
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11
The role of the immunoproteasome in interferon-γ-mediated microglial activation
Published in Scientific reports (24-08-2017)“…Microglia regulate the brain microenvironment by sensing damage and neutralizing potentially harmful insults. Disruption of central nervous system (CNS)…”
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12
Genetic diversity of HHV8 subtypes in South Africa: A5 subtype is associated with extensive disease in AIDS-KS
Published in Journal of medical virology (01-02-2016)“…Human herpes virus 8 (HHV8) is the etiological agent of all forms of Kaposi's sarcoma (KS). Six major subtypes (A‐F), based on genetic variability of open…”
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13
A high-throughput genome-wide RNAi screen identifies modifiers of survival motor neuron protein
Published in Cell reports (Cambridge) (11-05-2021)“…Spinal muscular atrophy (SMA) is a debilitating neurological disorder marked by degeneration of spinal motor neurons and muscle atrophy. SMA results from…”
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14
Transcriptional Regulation of Oncogenic Protein Kinase Cϵ (PKCϵ) by STAT1 and Sp1 Proteins
Published in The Journal of biological chemistry (11-07-2014)“…Overexpression of PKCϵ, a kinase associated with tumor aggressiveness and widely implicated in malignant transformation and metastasis, is a hallmark of…”
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15
Impact assessment of a community-based animal health project in Dollo Ado Dollo Bay districts, southern Ethiopia
Published in Tropical animal health and production (2005)“…Participatory methods were used to assess the impact of a community-based animal health worker (CAHW) project in two remote pastoralist districts of Ethiopia…”
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16
Risk factors for multidrug resistant tuberculosis patients in Amhara National Regional State
Published in African health sciences (01-06-2015)“…Background: Multidrug resistant tuberculosis(MDR-TB) is becoming a major threat to tuberculosis control programs in Ethiopia. Objectives: To determine risk…”
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17
ML372 blocks SMN ubiquitination and improves spinal muscular atrophy pathology in mice
Published in JCI insight (17-11-2016)“…Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disease and one of the leading inherited causes of infant mortality. SMA results from…”
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18
EP2 receptor mediated cAMP release is augmented by PGF(2I-) activation of the FP receptor via the calcium-calmodulin pathway
Published in Cellular signalling (01-01-2010)“…Prostaglandins exert their effects on target cells by coupling to specific G protein-coupled receptors (GPCRs) that are often co-expressed in the same cells…”
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Antibiogram of E. coli serotypes isolated from children aged under five with acute diarrhea in Bahir Dar town
Published in African health sciences (01-01-2015)“…Background: Diarrheal disease and its complications remain a major cause of morbidity and mortality in children. The prevalence and antibiogram of E. coli as…”
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20
Autosomal recessive hypercholesterolaemia: Discrimination of ARH protein and LDLR function in the homozygous FH phenotype
Published in Clinica chimica acta (01-03-2007)“…Phenocopies of homozygous familial hypercholesterolemia (hoFH) having autosomal recessive inheritance, were recently found to arise from defects in the LDL…”
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