Search Results - "Abeni, Edoardo"
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Effects of miR-193a and sorafenib on hepatocellular carcinoma cells
Published in Molecular cancer (13-12-2013)“…Hepatocellular carcinoma (HCC) is a challenging malignancy of global importance, it is the third most common cause of cancer-related mortality worldwide. In…”
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Transmembrane Protein TMEM230, Regulator of Glial Cell Vascular Mimicry and Endothelial Cell Angiogenesis in High-Grade Heterogeneous Infiltrating Gliomas and Glioblastoma
Published in International journal of molecular sciences (01-04-2024)“…High-grade gliomas (HGGs) and glioblastoma multiforme (GBM) are characterized by a heterogeneous and aggressive population of tissue-infiltrating cells that…”
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Biological Function of MicroRNA193a-3p in Health and Disease
Published in International journal of genomics (01-01-2017)“…MicroRNAs (miRNAs) are a class of small noncoding RNAs that act mainly as negative regulators of gene expression. Several studies demonstrated that miRNAs take…”
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Transmembrane Protein TMEM230, a Target of Glioblastoma Therapy
Published in Frontiers in cellular neuroscience (17-11-2021)“…Glioblastomas (GBM) are the most aggressive tumors originating in the brain. Histopathologic features include circuitous, disorganized, and highly permeable…”
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Sorafenib induces variations of the DNA methylome in HA22T/VGH human hepatocellular carcinoma-derived cells
Published in International journal of oncology (01-07-2017)“…Sorafenib is currently used to treat advanced and/or unresectable hepatocellular carcinoma (HCC), but the increase of the median survival was only 3 months…”
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Human hepatocellular carcinoma cell-specific miRNAs reveal the differential expression of miR-24 and miR-27a in cirrhotic/non-cirrhotic HCC
Published in International journal of oncology (01-02-2013)“…microRNAs (miRs) are 18-25 nucleotide non-coding RNAs that regulate gene expression in several physiological and pathological conditions. To gather more…”
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Analysis of a nanoparticle‑enriched fraction of plasma reveals miRNA candidates for Down syndrome pathogenesis
Published in International journal of molecular medicine (01-06-2019)“…Down syndrome (DS) is caused by the presence of part or all of a third copy of chromosome 21. DS is associated with several phenotypes, including intellectual…”
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Transmembrane protein TMEM230, regulator of metalloproteins and motor proteins in gliomas and gliosis
Published in Advances in protein chemistry and structural biology (2024)“…Glial cells provide physical and chemical support and protection for neurons and for the extracellular compartments of neural tissue through secretion of…”
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Single-cell transcriptomic analysis to identify endomembrane regulation of metalloproteins and motor proteins in autoimmunity
Published in Advances in protein chemistry and structural biology (2024)“…TMEM230 promotes antigen processing, trafficking, and presentation by regulating the endomembrane system of membrane bound organelles (lysosomes, proteosomes…”
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Long-term culture of patient-derived mammary organoids in non-biogenic electrospun scaffolds for identifying metalloprotein and motor protein activities in aging and senescence
Published in Advances in protein chemistry and structural biology (2024)“…We recently identified TMEM230 as a master regulator of the endomembrane system of cells. TMEM230 expression is necessary for promoting motor protein dependent…”
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Molecular characterization of LASP-1 expression reveals vimentin as its new partner in human hepatocellular carcinoma cells
Published in International journal of oncology (01-05-2015)“…Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related mortality worldwide. We have previously reported that LASP-1 is a downstream…”
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DNA methylation variations in familial female and male breast cancer
Published in Oncology letters (01-06-2021)“…In total, ~25% of familial breast cancer (BC) is attributed to germline mutations of the BRCA1 and BRCA2 genes, while the rest of the cases are included in the…”
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