Search Results - "Abelson, John N."

Crystal Structure of a DEAD Box Protein from the Hyperthermophile Methanococcus jannaschii by Story, Randall M., Li, Hong, Abelson, John N.

“…We have determined the structure of a DEAD box putative RNA helicase from the hyperthermophile Methanococcus jannaschii. Like other helicases, the protein…”
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Prp43: an RNA helicase-like factor involved in spliceosome disassembly by Arenas, J.E, Abelson, J.N

“…The Saccharomyces cerevisiae genes PRP2, PRP16, and PRP22 encode pre-mRNA splicing factors that belong to the highly conserved "DEAH" family of putative RNA…”
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The Transfer RNA Identity Problem: A Search for Rules by Saks, Margaret E., Sampson, Jeffrey R., Abelson, John N.

“…Correct recognition of transfer RNAs (tRNAs) by aminoacyl-tRNA synthetases is central to the maintenance of translational fidelity. The hypothesis that…”
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Probing the Role of an Active Site Aspartic Acid in Dihydrofolate Reductase by Karginov, Vladimir A, Mamaev, Sergey V, An, Haoyun, Van Cleve, Mark D, Hecht, Sidney M, Komatsoulis, George A, Abelson, John N

“…Analogues of E. coli dihydrofolate reductase (DHFR) containing modified amino acids at single, predetermined sites have been prepared. This was accomplished by…”
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The Yeast tRNA Splicing Endonuclease: A Tetrameric Enzyme with Two Active Site Subunits Homologous to the Archaeal tRNA Endonucleases by Trotta, Christopher R, Miao, Feng, Arn, Eric A, Stevens, Scott W, Ho, Calvin K, Rauhut, Reinhard, Abelson, John N

“…The splicing of tRNA precursors is essential for the production of mature tRNA in organisms from all major phyla. In yeast, the tRNA splicing endonuclease is…”
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Directed Mutagenesis of Dihydrofolate Reductase by Villafranca, Jesus E., Howell, Elizabeth E., Voet, Donald H., Strobel, Marjorie S., Ogden, Richard C., Abelson, John N., Kraut, Joseph

“…Three mutations of the enzyme dihydrofolate reductase were constructed by oligonucleotide-directed mutagenesis of the cloned Escherichia coli gene. The…”
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Nicotinic Receptor Binding Site Probed with Unnatural Amino Acid Incorporation in Intact Cells by Nowak, Mark W., Kearney, Patrick C., Sampson, Jeffrey R., Saks, Margaret E., Labarca, Cesar G., Silverman, Scott K., Zhong, Wenge, Thorson, Jon, Abelson, John N., Davidson, Norman, Schultz, Peter G., Dougherty, Dennis A., Lester, Henry A.

“…The nonsense codon suppression method for unnatural amino acid incorporation has been applied to intact cells and combined with electrophysiological analysis…”
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In vitro trans-splicing in Saccharomyces cerevisiae by Ghetti, A. (California Institute of Technology, Pasadena, CA.), Abelson, J.N

“…The interactions established at the 5'-splice site during spliceosome assembly are likely to be important for both precise recognition of the upstream intron…”
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An Engineered Tetrahymena tRNAGln for in Vivo Incorporation of Unnatural Amino Acids into Proteins by Nonsense Suppression by Saks, M E, Sampson, J R, Nowak, M W, Kearney, P C, Du, F, Abelson, J N, Lester, H A, Dougherty, D A

“…A new tRNA, THG73, has been designed and evaluated as a vehicle for incorporating unnatural amino acids site-specifically into proteins expressed in vivo using…”
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The DEAH-box protein PRP22 is an ATPase that mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes by Wagner, John D.O., Jankowsky, Eckhard, Company, Mahshid, Pyle, Anna Marie, Abelson, John N.

“…Of the proteins required for pre‐mRNA splicing, at least four, the DEAH‐box proteins, are closely related due to the presence of a central ‘RNA helicase‐like’…”
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The 2'-5' RNA ligase of Escherichia coli. Purification, cloning, and genomic disruption by Arn, E A, Abelson, J N

“…An RNA ligase previously detected in extracts of Escherichia coli is capable of joining Saccharomyces cerevisiae tRNA splicing intermediates in the absence of…”
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The 2′-5′ RNA Ligase of Escherichia coli by Eric A. Arn, John N. Abelson

“…An RNA ligase previously detected in extracts of Escherichia coli is capable of joining Saccharomyces cerevisiae tRNA splicing intermediates in the absence of…”
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The 2′-5′ RNA Ligase of Escherichia coli by Arn, Eric A., Abelson, John N.

“…An RNA ligase previously detected in extracts of Escherichia coli is capable of joining Saccharomyces cerevisiae tRNA splicing intermediates in the absence of…”
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The Saccharomyces cerevisiae PRP21 gene product is an integral component of the prespliceosome by Arenas, Jaime E., Abelson, John N.

“…In Saccharomyces cerevisiae, the prp21 mutation causes accumulation of unspliced pre-mRNA at the nonpermissive temperature. We have cloned the PRP21 gene by…”
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PRP4: a Protein of the Yeast U4/U6 Small Nuclear Ribonucleoprotein Particle by Banroques, Josette, Abelson, John N.

“…The Saccharomyces cerevisiae prp mutants (prp2 through prp11) are known to be defective in pre-mRNA splicing at nonpermissive temperatures. We have sequenced…”
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Preparation and fractionation of yeast splicing extract by Cheng, S C, Newman, A N, Lin, R J, McFarland, G D, Abelson, J N

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In vitro synthesis of end-mature, intron-containing transfer RNAs by Reyes, V M, Abelson, J N

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Highly purified transfer RNA splicing endonuclease from Saccharomyces cerevisiae by Green, P R, Abelson, J N

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Nucleotide sequence of ORF2: an open reading frame upstream of the tRNA ligase gene by KOMATSOULIS, G. A, WESTAWAY, S. K, ABELSON, J. N

“…During the course of sequencing the tRNA ligase gene from the yeast Saccharomyces cerevisiae , an open reading frame, ORF2, was discovered in its vicinity…”
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Purification of yeast transfer RNA ligase by Xu, Q, Phizicky, E M, Greer, C L, Abelson, J N

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