Search Results - "Abellan, Juan J."

Estimation of Treatment Policy Estimands for Continuous Outcomes Using Off-Treatment Sequential Multiple Imputation by Drury, Thomas, Abellan, Juan J, Best, Nicky, White, Ian R

“…The estimands framework outlined in ICH E9 (R1) describes the components needed to precisely define the effects to be estimated in clinical trials, which…”
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Historical controls in clinical trials: a note on linking Pocock’s model with the robust mixture priors by Callegaro, Andrea, Galwey, Nicholas, Abellan, Juan J

“…Summary Several Bayesian methods have been proposed to borrow information dynamically from historical controls in clinical trials. In this note, we identify…”
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Statistical analysis of actigraphy data with generalised additive models by Lisi, Edoardo, Abellan, Juan J.

“…There is a growing interest in the use of physical activity data in clinical studies, particularly in diseases that limit mobility in patients. High‐frequency…”
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Assessing Gut Microbial Diversity from Feces and Rectal Mucosa by Durbán, Ana, Abellán, Juan J, Jiménez-Hernández, Nuria, Ponce, Marta, Ponce, Julio, Sala, Teresa, D'Auria, Giuseppe, Latorre, Amparo, Moya, Andrés

“…Gut microbiota is the most complex bacterial community in the human body and its study may give important clues to the etiology of different intestinal…”
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Instability of the faecal microbiota in diarrhoea-predominant irritable bowel syndrome by Durbán, Ana, Abellán, Juan J., Jiménez-Hernández, Nuria, Artacho, Alejandro, Garrigues, Vicente, Ortiz, Vicente, Ponce, Julio, Latorre, Amparo, Moya, Andrés

“…Abstract The irritable bowel syndrome (IBS) is a functional gastrointestinal disorder with a largely unknown aetiology and a wide range of symptoms. Most…”
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Estimation of a treatment policy estimand for time to event data using data collected post discontinuation of randomised treatment by Hartley, Benjamin, Drury, Thomas, Lettis, Sally, Mayer, Bhabita, Keene, Oliver N., Abellan, Juan J.

“…Discontinuation from randomised treatment is a common intercurrent event in clinical trials. When the target estimand uses a treatment policy strategy to deal…”
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Environmental inequity in England: Small area associations between socio-economic status and environmental pollution by Briggs, David, Abellan, Juan J., Fecht, Daniela

“…Recent studies have suggested that more deprived people tend to live in areas characterised by higher levels of environmental pollution. If generally true,…”
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Bayesian spatio-temporal analysis of joint patterns of male and female lung cancer risks in Yorkshire (UK) by Richardson, Sylvia, Abellan, Juan J, Best, Nicky

“…Recent advances in disease mapping have focused first on including the time dimension, thus giving rise to spatio-temporal analysis of the variation of disease…”
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Spatial Analysis of the Relationship between Mortality from Cardiovascular and Cerebrovascular Disease and Drinking Water Hardness by Ferrándiz, Juan, Abellán, Juan J., Gómez-Rubio, Virgilio, López-Quílez, Antonio, Sanmartín, Pilar, Abellán, Carlos, Martínez-Beneito, Miguel A., Melchor, Inmaculada, Vanaclocha, Hermelinda, Zurriaga, Óscar, Ballester, Ferrán, Gil, José M., Pérez-Hoyos, Santiago, Ocaña, Ricardo

“…Previously published scientific papers have reported a negative correlation between drinking water hardness and cardiovascular mortality. Some ecologic and…”
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Treatment policy estimands for recurrent event data using data collected after cessation of randomised treatment by Roger, James H., Bratton, Daniel J., Mayer, Bhabita, Abellan, Juan J., Keene, Oliver N.

“…SUMMARY In the past, many clinical trials have withdrawn subjects from the study when they prematurely stopped their randomised treatment and have therefore…”
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Structural alterations of faecal and mucosa-associated bacterial communities in irritable bowel syndrome by Durbán, Ana, Abellán, Juan J., Jiménez-Hernández, Nuria, Salgado, Patricia, Ponce, Marta, Ponce, Julio, Garrigues, Vicente, Latorre, Amparo, Moya, Andrés

“…Summary Irritable bowel syndrome (IBS) is the most common functional gastrointestinal disorder in western countries. Previous studies on IBS, mostly based on…”
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Bayesian model to detect phenotype-specific genes for copy number data by Gonzalez, Juan R, Abellan, Carlos, Abellan, Juan J

“…An important question in genetic studies is to determine those genetic variants, in particular CNVs, that are specific to different groups of individuals. This…”
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Tramadol article conclusion troubling by Abellan, Juan J, van Niel, Johannes C G, Eerdekens, Mariëlle

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Bayesian shared spatial-component models to combine and borrow strength across sparse disease surveillance sources by Ancelet, Sophie, Abellan, Juan J., Del Rio Vilas, Víctor J., Birch, Colin, Richardson, Sylvia

“…When analyzing the geographical variations of disease risk, one common problem is data sparseness. In such a setting, we investigate the possibility of using…”
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Bayesian analysis of the multivariate geographical distribution of the socio-economic environment in England by Abellan, Juan J., Fecht, Daniela, Best, Nicky, Richardson, Sylvia, Briggs, David J.

“…In this paper we analyse the geographical distribution of the Indices of Deprivation 2004, a set of seven area‐based indices measuring multiple dimensions of…”
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Assessing the social class of children from parental information to study possible social inequalities in health outcomes by Zurriaga, Oscar, Martı́ínez-Beneito, Miguel A, Abellán, Juan J, Carda, Carmen

“…When the subjects are children, the assessment of social class must be made indirectly from parental data. We propose correspondence analysis as a method for…”
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Estimation of treatment policy estimands for continuous outcomes using off treatment sequential multiple imputation by Drury, Thomas, Abellan, Juan J, Best, Nicky, White, Ian R

“…The estimands framework outlined in ICH E9 (R1) describes the components needed to precisely define the effects to be estimated in clinical trials, which…”
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Spatio-temporal patterns of bladder cancer incidence in Utah (1973-2004) and their association with the presence of toxic release inventory sites by Fortunato, Léa, Abellan, Juan José, Beale, Linda, LeFevre, Sam, Richardson, Sylvia

“…The authors analyse the spatio-temporal variations of the incidence of bladder cancer between 1973 and 2004 in Utah at the census tract level (496 areas) to…”
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Awareness and use of quantitative decision-making methods in pharmaceutical development by Thömmes, Guido, Sailer, Martin Oliver, Bonnet, Nicolas, Carlton, Alex, Abellan, Juan J, Robert, Veronique

“…The pharmaceutical industry has experienced increasing costs and sustained high attrition rates in drug development over the last years. One proposal that…”
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Implementation and pratical aspects of quantitative decision-making in clinical drug development by Abellan, Juan J, Bonnet, Nicolas, Carlton, Alex, Frewer, Paul, Götte, Heiko, Lawo, John-Philip, Madsen, Jesper, Sailer, Oliver, Thömmes, Guido, Saint-Hilary, Gaëlle

“…Quantitative decision-making (QDM) principles address the issues related to the mapping of results to decisions, the synthesis of information and the…”
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