Search Results - "Abela, Andrew R"

Median raphe serotonin neurons promote anxiety-like behavior via inputs to the dorsal hippocampus by Abela, Andrew R., Browne, Caleb J., Sargin, Derya, Prevot, Thomas D., Ji, Xiao Dong, Li, Zhaoxia, Lambe, Evelyn K., Fletcher, Paul J.

“…Anxiety disorders may be mediated in part by disruptions in serotonin (5-hydroxytryptamine, 5-HT) system function. Behavioral measures of approach-avoidance…”
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Noradrenergic α2A-receptor stimulation in the ventral hippocampus reduces impulsive decision-making by Abela, Andrew R., Chudasama, Yogita

“…Rationale Guanfacine, an α 2A -adrenergic receptor agonist, is currently in use for treatment of a variety of psychiatric disorders that are associated with…”
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Assessing the stability of responding of male mice in the touchscreen 5 choice serial reaction time task: Focus on premature responding by Rahbarnia, Arya, Abela, Andrew R, Fletcher, Paul J

“…The five-choice serial reaction time task (5CSRTT) is a test of attention that provides a well-validated ancillary measure of impulsive action, measured by…”
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Dissociable contributions of the ventral hippocampus and orbitofrontal cortex to decision-making with a delayed or uncertain outcome by Abela, Andrew R., Chudasama, Yogita

“…In this study, we examined how risk and delay influence rats' decision‐making, and the role of the ventral hippocampus (VHC) and orbitofrontal cortex (OFC) in…”
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Hippocampal interplay with the nucleus accumbens is critical for decisions about time by Abela, Andrew R., Duan, Yiran, Chudasama, Yogita

“…Human cognition depends upon the capacity to make decisions in the present that bear upon outcomes in the future. The nucleus accumbens, a recipient of direct…”
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Adolescent exposure to Δ9-tetrahydrocannabinol delays acquisition of paired-associates learning in adulthood by Abela, Andrew R., Rahbarnia, Arya, Wood, Suzanne, Lê, Anh D., Fletcher, Paul J.

“…Rationale and objectives Adolescence is a sensitive period of brain development, during which there may be a heightened vulnerability to the effects of drug…”
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Dorsal raphe serotonin neurons inhibit operant responding for reward via inputs to the ventral tegmental area but not the nucleus accumbens: evidence from studies combining optogenetic stimulation and serotonin reuptake inhibition by Browne, Caleb J, Abela, Andrew R, Chu, Duong, Li, Zhaoxia, Ji, Xiaodong, Lambe, Evelyn K, Fletcher, Paul J

“…The monoamine neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts an inhibitory influence over motivation, but the circuits mediating this are…”
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Intraneuronal Amyloid Beta Accumulation Disrupts Hippocampal CRTC1-Dependent Gene Expression and Cognitive Function in a Rat Model of Alzheimer Disease by Wilson, Edward N, Abela, Andrew R, Do Carmo, Sonia, Allard, Simon, Marks, Adam R, Welikovitch, Lindsay A, Ducatenzeiler, Adriana, Chudasama, Yogita, Cuello, A Claudio

“…In Alzheimer disease (AD), the accumulation of amyloid beta (Aβ) begins decades before cognitive symptoms and progresses from intraneuronal material to…”
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Clozapine reliably increases the motivation for food: parsing the role of the 5-HT2c and H1 receptors by Abela, Andrew R., Ji, Xiao Dong, Li, Zhaoxia, Lê, Anh D., Fletcher, Paul J.

“…Rationale and objectives Although clozapine is effective in treating schizophrenia, it is associated with adverse side effects including weight gain and…”
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Prenatal disruption of D1R-SynGAP complex causes cognitive deficits in adulthood by Lai, Terence K.Y., Abela, Andrew R., Su, Ping, Fletcher, Paul J., Liu, Fang

“…γ-aminobutyric acid (GABA)-ergic interneurons are essential for the physiological function of the mammalian central nervous system. Dysregulated GABAergic…”
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Clozapine reduces nicotine self‐administration, blunts reinstatement of nicotine‐seeking but increases responding for food by Abela, Andrew R., Li, Zhaoxia, Lê, Anh D., Fletcher, Paul J.

“…People with schizophrenia display significantly higher rates of smoking than the general population, which may be due to an interaction between nicotine and…”
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Inhibitory control deficits in rats with ventral hippocampal lesions by Abela, Andrew R, Dougherty, Stephen D, Fagen, Erin D, Hill, Carolyn J R, Chudasama, Y

“…Two experiments are reported in which rats with selective hippocampal lesions were tested on 2 prefrontal-dependent tasks. In Experiment 1, we compared the…”
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Effects of acute olanzapine exposure on central insulin-mediated regulation of whole body fuel selection and feeding by Castellani, Laura N., Wilkin, Jennifer, Abela, Andrew R., Benarroch, Louise, Ahasan, Zohra, Teo, Celine, Wilson, Virginia, Kowalchuk, Chantel, Giacca, Adria, Remington, Gary J., Hahn, Margaret K.

“…•Olanzapine increases preference for fatty acid oxidation in light and dark phases.•Central insulin decreases food intake and promotes dark phase fatty acid…”
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Noradrenergic alpha sub(2A)-receptor stimulation in the ventral hippocampus reduces impulsive decision-making by Abela, Andrew R, Chudasama, Yogita

“…Rationale: Guanfacine, an alpha sub(2A)-adrenergic receptor agonist, is currently in use for treatment of a variety of psychiatric disorders that are…”
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Noradrenergic [α.sub.2A]-receptor stimulation in the ventral hippocampus reduces impulsive decision-making by Abela, Andrew R, Chudasama, Yogita

“…Rationale Guanfacine, an [α.sub.2A]-adrenergic receptor agonist, is currently in use for treatment of a variety of psychiatric disorders that are associated…”
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Noradrenergic [alpha]^sub 2A^-receptor stimulation in the ventral hippocampus reduces impulsive decision-making by Abela, Andrew R, Chudasama, Yogita

“…Guanfacine, an [alpha]^sub 2A^-adrenergic receptor agonist, is currently in use for treatment of a variety of psychiatric disorders that are associated with…”
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Clozapine reliably increases the motivation for food: parsing the role of the 5-HT.sub.2c and H.sub.1 receptors by Abela, Andrew R, Ji, Xiao Dong, Li, Zhaoxia, Lê, Anh D, Fletcher, Paul J

“…Rationale and objectives Although clozapine is effective in treating schizophrenia, it is associated with adverse side effects including weight gain and…”
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Adolescent exposure to [DELTA]9-tetrahydrocannabinol delays acquisition of paired-associates learning in adulthood by Abela, Andrew R, Rahbarnia, Arya, Wood, Suzanne, Lê, Anh D, Fletcher, Paul J

“…Rationale and objectives Adolescence is a sensitive period of brain development, during which there may be a heightened vulnerability to the effects of drug…”
Get full text

Clozapine reliably increases the motivation for food: parsing the role of the 5-HT 2c and H 1 receptors by Abela, Andrew R, Ji, Xiao Dong, Li, Zhaoxia, Lê, Anh D, Fletcher, Paul J

“…Although clozapine is effective in treating schizophrenia, it is associated with adverse side effects including weight gain and metabolic syndrome. Despite…”
Get full text