Search Results - "Abel, Yoann"
-
1
SnoRNAs and the emerging class of sdRNAs: Multifaceted players in oncogenesis
Published in Biochimie (01-09-2019)“…Small nucleolar RNAs are generally involved in the modification of target ribosomal RNAs. Other possible functions recently emerged with the discovery of the…”
Get full text
Journal Article -
2
The RPAP3-Cterminal domain identifies R2TP-like quaternary chaperones
Published in Nature communications (29-05-2018)“…R2TP is an HSP90 co-chaperone that assembles important macro-molecular machineries. It is composed of an RPAP3-PIH1D1 heterodimer, which binds the two…”
Get full text
Journal Article Web Resource -
3
Small non-coding RNAs: a quick look in the rearview mirror
Published in Methods in molecular biology (Clifton, N.J.) (2015)“…The revolution of miRNA discovery, in the early 2000s, shed a new light in the exciting field of small non-coding RNAs. Since then, and owing to outstanding…”
Get more information
Journal Article -
4
Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex
Published in Structure (London) (04-09-2018)“…RPAP3 and PIH1D1 are part of the HSP90 co-chaperone R2TP complex involved in the assembly process of many molecular machines. In this study, we performed a…”
Get full text
Journal Article Web Resource -
5
Gene expression knockdown by transfection of siRNAs into mammalian cells
Published in Methods in molecular biology (Clifton, N.J.) (2015)“…SiRNA induced gene silencing or RNA interference is a powerful tool to knock down gene expression and perform gene function studies. In this chapter, we…”
Get more information
Journal Article -
6
The interaction between RPAP3 and TRBP reveals a possible involvement of the HSP90/R2TP chaperone complex in the regulation of miRNA activity
Published in Nucleic acids research (28-02-2022)“…Abstract MicroRNAs silence mRNAs by guiding the RISC complex. RISC assembly occurs following cleavage of pre-miRNAs by Dicer, assisted by TRBP or PACT, and the…”
Get full text
Journal Article -
7
NOPCHAP1 is a PAQosome cofactor that helps loading NOP58 on RUVBL1/2 during box C/D snoRNP biogenesis
Published in Nucleic acids research (25-01-2021)“…Abstract The PAQosome is a large complex composed of the HSP90/R2TP chaperone and a prefoldin-like module. It promotes the biogenesis of cellular machineries…”
Get full text
Journal Article -
8
Deciphering cellular and molecular determinants of human DPCD protein in complex with RUVBL1/RUVBL2 AAA-ATPases
Published in Journal of molecular biology (15-10-2022)“…[Display omitted] •DPCD is a new RUVBL1/RUVBL2 cofactor.•3 DPCD interact with 1 RUVBL1/RUVBL2 heterohexamer with sub-micromolar affinity.•DPCD regulates the…”
Get full text
Journal Article -
9
Beyond usual functions of snoRNAs
Published in M.S. Médecine sciences (01-03-2014)“…Small nucleolar RNAs or snoRNAs, principally implicated in post-transcriptional chemical modification of other RNAs, were among the first non-coding RNA…”
Get more information
Journal Article