Search Results - "Abel, Renata"
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Allosteric Modulation of the CB1 Cannabinoid Receptor by Cannabidiol-A Molecular Modeling Study of the N-Terminal Domain and the Allosteric-Orthosteric Coupling
Published in Molecules (Basel, Switzerland) (23-04-2021)“…The CB cannabinoid receptor (CB R) contains one of the longest N termini among class A G protein-coupled receptors. Mutagenesis studies suggest that the…”
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Reynoutria Rhizomes as a Natural Source of SARS-CoV-2 Mpro Inhibitors-Molecular Docking and In Vitro Study
Published in Pharmaceuticals (Basel, Switzerland) (29-07-2021)“…More than a year has passed since the world began to fight the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for the…”
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Cytotoxic Effect of Vanicosides A and B from Reynoutria sachalinensis Against Melanotic and Amelanotic Melanoma Cell Lines and in silico Evaluation for Inhibition of BRAFV600E and MEK1
Published in International journal of molecular sciences (29-06-2020)“…Vanicosides A and B are the esters of hydroxycinnamic acids with sucrose, occurring in a few plant species from the Polygonaceae family. So far, vanicosides A…”
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SuperTCM: A biocultural database combining biological pathways and historical linguistic data of Chinese Materia Medica for drug development
Published in Biomedicine & pharmacotherapy (01-12-2021)“…Botanicals used in Traditional Chinese Medicine (TCM) are a rich source for drug discovery and provide models for multi-component drug development. To…”
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Computational Prediction of Potential Inhibitors of the Main Protease of SARS-CoV-2
Published in Frontiers in chemistry (23-12-2020)“…The rapidly developing pandemic, known as coronavirus disease 2019 (COVID-19) and caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),…”
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Norditerpenoids with Selective Anti-Cholinesterase Activity from the Roots of Perovskia atriplicifolia Benth
Published in International journal of molecular sciences (23-06-2020)“…Inhibition of cholinesterases remains one of a few available treatment strategies for neurodegenerative dementias such as Alzheimer's disease and related…”
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A Comparative Analysis of COVID-19 Vaccines Based on over 580,000 Cases from the Vaccination Adverse Event Reporting System
Published in Vaccines (Basel) (01-03-2022)“…Background: The COVID-19 pandemic is being battled via the largest vaccination campaign in history, with more than eight billion doses administered thus far…”
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Oxidative testicular injury: effect of l-leucine on redox, cholinergic and purinergic dysfunctions, and dysregulated metabolic pathways
Published in Amino acids (01-03-2021)“…The antioxidant and anti-proinflammatory activities of l -leucine were investigated on oxidative testicular injury, ex vivo. In vitro analysis revealed l…”
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Betulin and Its Derivatives Reduce Inflammation and COX-2 Activity in Macrophages
Published in Inflammation (01-04-2023)“…Betulin is a heavily studied natural compound for its use as an anticancer or pro-regenerative agent. The structural similarity between betulin to steroids…”
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Ontogenetic and trans-generational variation of essential oil composition in Agastache rugosa
Published in Industrial crops and products (01-03-2017)“…[Display omitted] •Variability of Agastache rugosa progeny essential oil composition is influenced by the mother plant age .•Older plants obtained from seeds…”
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Non-psychotropic cannabinoids as inhibitors of TET1 protein
Published in Bioorganic chemistry (01-07-2022)“…[Display omitted] •CBD and CBN are potent inhibitor of TET1 protein (Fe(II) depended dioxygenase).•Their interact via hydrophobic interactions, hydrogen…”
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Analysis of Antioxidant Polyphenols in Loquat Leaves using HPLC-based Activity Profiling
Published in Natural product communications (01-02-2017)“…Leaves of Eriobotryajaponica (loquat) have been used in Traditional Chinese Medicine with beneficial effects in numerous diseases. Extracts from loquat leaves…”
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PARA ALÉM DA RAZÃO: EXPERIÊNCIAS RADICAIS DE ENSINO-APRENDIZAGEM EM CIÊNCIAS SOCIAIS (UMA REFLEXÃO SOBRE O CURSO TÓPICOS UTÓPICOS, 2017-2018)
Published in Revista temas em educação : RTE (31-05-2021)“…O artigo relata experiências pedagógicas radicais realizadas entre 2017 e 2018, no âmbito de um curso de extensão da Universidade Federal de Santa Catarina,…”
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