Search Results - "Abel, Evan Dale"

Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy by Troncoso, Rodrigo, Vicencio, Jose Miguel, Parra, Valentina, Nemchenko, Andriy, Kawashima, Yuki, del Campo, Andrea, Toro, Barbra, Battiprolu, Pavan K., Aranguiz, Pablo, Chiong, Mario, Yakar, Shoshana, Gillette, Thomas G., Hill, Joseph A., Abel, Evan Dale, LeRoith, Derek, Lavandero, Sergio

“…Aims Insulin-like growth factor 1 (IGF-1) is known to exert cardioprotective actions. However, it remains unknown if autophagy, a major adaptive response to…”
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Diabetic cardiomyopathy, causes and effects by Boudina, Sihem, Abel, Evan Dale

“…Diabetes is associated with increased incidence of heart failure even after controlling for coronary artery disease and hypertension. Thus, as diabetic…”
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Increased Glucose Availability Attenuates Myocardial Ketone Body Utilization by Brahma, Manoja K, Ha, Chae-Myeong, Pepin, Mark E, Mia, Sobuj, Sun, Zhihuan, Chatham, John C, Habegger, Kirk M, Abel, Evan Dale, Paterson, Andrew J, Young, Martin E, Wende, Adam R

“…Background Perturbations in myocardial substrate utilization have been proposed to contribute to the pathogenesis of cardiac dysfunction in diabetic subjects…”
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Receptor activator of nuclear factor-κB ligand is a novel inducer of myocardial inflammation by OCK, Sangmi, AHN, Jihyun, GOO TAEG OH, DALE ABEL, Evan, WOO JIN PARK, MIN, Jeong-Ki, KIM, Jaetaek, SEOK HONG LEE, PARK, Hongryeol, JANG WON SON, JAE GYUN OH, DONG KWON YANG, WANG SOO LEE, KIM, Ho-Shik, RHO, Jaerang

“…Although increased levels of myocardial receptor activator of nuclear factor (NF)-κB ligand (RANKL) have been reported in heart failure, the role of this…”
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Cardiomyocyte specific deletion of Crif1 causes mitochondrial cardiomyopathy in mice by Shin, Juhee, Lee, Seok Hong, Kwon, Min-Chul, Yang, Dong Kwon, Seo, Ha-Rim, Kim, Jaetaek, Kim, Yoon-Young, Im, Sun-Kyoung, Abel, Evan Dale, Kim, Kyong-Tai, Park, Woo Jin, Kong, Young-Yun

“…Mitochondria are key organelles dedicated to energy production. Crif1, which interacts with the large subunit of the mitochondrial ribosome, is indispensable…”
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Abstract P2077: FoxO3 Transcription Factor Regulates Myocyte Contractility And Calcium Homeostasis In Diabetic Cardiomyopathy by Bhardwaj, Gourav, Penniman, Christie, Tadinada, Satya Murthy, Shi, Qian, Chen, Biyi, Nowers, Colette, Weatherford, Eric T, Abel, Evan dale, Song, Long-Sheng, O'Neill, Brian

“…Abstract only Diabetes is a risk factor for heart failure with preserved ejection fractions (HFpEF). Calcium (Ca 2+ ) mishandling and diastolic abnormalities…”
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Insulin stimulates mitochondrial fusion and function in cardiomyocytes via the Akt-mTOR-NFκB-Opa-1 signaling pathway by Parra, Valentina, Verdejo, Hugo E, Iglewski, Myriam, Del Campo, Andrea, Troncoso, Rodrigo, Jones, Deborah, Zhu, Yi, Kuzmicic, Jovan, Pennanen, Christian, Lopez-Crisosto, Camila, Jaña, Fabián, Ferreira, Jorge, Noguera, Eduard, Chiong, Mario, Bernlohr, David A, Klip, Amira, Hill, Joseph A, Rothermel, Beverly A, Abel, Evan Dale, Zorzano, Antonio, Lavandero, Sergio

“…Insulin regulates heart metabolism through the regulation of insulin-stimulated glucose uptake. Studies have indicated that insulin can also regulate…”
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Cardiac Complications of Obesity by Abel, Evan Dale

“…Obesity is an independent risk factor for the development of heart failure. Although the mechanisms are multifactorial and include increased coronary…”
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ULK1 Regulates Hepatic Lipid Metabolism via Autophagy Independent Mechanisms by Koo, Young Do, Castillo, Romilia Tatiana, Hinton, Antentor Othrell, Abel, Evan Dale

“…Non-alcoholic steatohepatitis (NASH), a major complication of obesity, diabetes, and metabolic syndrome has emerged as a leading cause of chronic liver disease…”
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SUN-572 Estrogen Synergistically Interacts with Optic Atrophy Protein 1 to Promote Thrombosis by Souvenir, Rhonda A, Renata, Alambert, Campbell, Robert, Hinton, Antentor O, Rondina, Matthew T, Abel, Evan Dale

“…Thrombosis is a major concern in: premenopausal females on oral contraceptives, menopausal women undergoing hormone replacement therapy, post-menopausal women…”
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SUN-LB118 Mice With Skeletal Muscle-Specific DRP1 Deficiency Are Resistant to Obesity and Diabetes Induced by a High Fat Diet by Jensen, Renato Daniel, Peterson, Joshua, Allington, Benjamin, Dieter, Alayna, Cheng, Linhai, Soto, Jamie, Alambert, Renata Pereira, Correia, Marcelo, Abel, Evan Dale

“…The skeletal muscle of type 2 diabetics exhibits mitochondrial dysfunction associated with increased mitochondrial fission. Dynamin-related protein 1 (DRP1) is…”
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Insulin stimulates mitochondrial fusion and function in cardiomyocytes via the Akt-mTOR-NF[kappa]B-Opa-1 signaling pathway by Parra, Valentina, Verdejo, Hugo E, Iglewski, Myriam, del Campo, Andrea, Troncoso, Rodrigo, Jones, Deborah, Zhu, Yi, Kuzmicic, Jovan, Pennanen, Christian, Lopez-Crisosto, Camila, Jana, Fabian, Ferreira, Jorge, Noguera, Eduard, Chiong, Mario, Bernlohr, David A, Klip, Amira, Hill, Joseph A, Rothermel, Beverly A, Abel, Evan Dale, Zorzano, Antonio, Lavandero, Sergio

“…Insulin regulates heart metabolism through the regulation of insulin-stimulated glucose uptake. Studies have indicated that insulin can also regulate…”
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Abstract 17000: Activation of Igf-1 Receptor Signaling by Hyperinsulinemia Suppresses Cardiac Autophagy Through Trb3/p62 Pathway by Pires, Karla Maria, Ilkun, Olesya, Buffolo, Maricio Augusto, Pei, Shaobo, Abel, Evan Dale, Boudina, Sihem

“…IntroductionInsulin and insulin-like growth factor (IGF) receptor signaling is a known suppressor of autophagy in the heart. Therefore, one would predict to…”
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Cardiac Glucose Transporter Deficiency Increases the Susceptibility of the Heart to Ischemic Injury by TIAN, RONG, PHAM, MARK, ABEL, EVAN DALE

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Cardiac Specific Knock Out of GLUT4 Leads to Mistargeting of IRAP in Heart Muscle by ABEL, EVAN DALE, KANDROR, VERA, HANEY, NAILIA, KANDROR, KONSTANTIN V

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