Search Results - "Abebe, Bayew Tsega"

Simultaneous Quantitative Analysis of Clarithromycin and Ranitidine, Probe Inhibitors of P-Glycoprotein and OCT1, to Evaluate Potential Pharmacokinetic Influence of Potential Transporter Substrates by Scheuch, Eberhard, Abebe, Bayew Tsega, Siegmund, Werner

“…Clartihromycin and ranitidine are accepted probe inhibitors in drug/drug interaction studies (DDI) with substrates of the multidrug transporters P-glycoprotein…”
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Effects of the P‐Glycoprotein Inhibitor Clarithromycin on the Pharmacokinetics of Intravenous and Oral Trospium Chloride: A 4‐Way Crossover Drug‐Drug Interaction Study in Healthy Subjects by Abebe, Bayew Tsega, Weiss, Michael, Modess, Christiane, Roustom, Tarek, Tadken, Tobias, Wegner, Danilo, Schwantes, Ulrich, Neumeister, Claudia, Schulz, Hans‐Ulrich, Scheuch, Eberhard, Siegmund, Werner

“…The quaternary ammonium compound trospium chloride is poorly absorbed from 2 “absorption windows” in the jejunum and cecum/ascending colon, respectively. To…”
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Pharmacokinetic Drug‐Drug Interactions Between Trospium Chloride and Ranitidine Substrates of Organic Cation Transporters in Healthy Human Subjects by Abebe, Bayew Tsega, Weiss, Michael, Modess, Christiane, Tadken, Tobias, Wegner, Danilo, Meyer, Marleen J., Schwantes, Ulrich, Neumeister, Claudia, Scheuch, Eberhard, Schulz, Hans‐Ulrich, Tzvetkov, Mladen, Siegmund, Werner

“…Trospium chloride, a muscarinic receptor blocker, is poorly absorbed with different rates from areas in the jejunum and the cecum/ascending colon. To evaluate…”
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