Search Results - "Abe, Kazumi"

Recombination of repeat elements generates somatic complexity in human genomes by Pascarella, Giovanni, Hon, Chung Chau, Hashimoto, Kosuke, Busch, Annika, Luginbühl, Joachim, Parr, Callum, Hin Yip, Wing, Abe, Kazumi, Kratz, Anton, Bonetti, Alessandro, Agostini, Federico, Severin, Jessica, Murayama, Shigeo, Suzuki, Yutaka, Gustincich, Stefano, Frith, Martin, Carninci, Piero

“…Non-allelic recombination between homologous repetitive elements contributes to evolution and human genetic disorders. Here, we combine short- and long-DNA…”
Get full text

Development of highly electron-deficient and less sterically-hindered phosphine ligands possessing 1,3,5-triazinyl groups by Abe, Kazumi, Kitamura, Masanori, Fujita, Hikaru, Kunishima, Munetaka

“…[Display omitted] •Highly electron-deficient and less sterically-hindered phosphine ligands.•Least steric hindrance to a metal center among triarylphosphine…”
Get full text

Perturbation of copper homeostasis is instrumental in early developmental arrest of intraerythrocytic Plasmodium falciparum by Asahi, Hiroko, Tolba, Mohammed Essa Marghany, Tanabe, Masanobu, Sugano, Sumio, Abe, Kazumi, Kawamoto, Fumihiko

“…Malaria continues to be a devastating disease. The elucidation of factors inducing asexual growth versus arrest of Plasmodium falciparum can provide…”
Get full text

Polycavernoside C and C2, the new analogs of the human lethal toxin polycavernoside A, from the red alga, Gracilaria edulis by Yotsu-Yamashita, Mari, Abe, Kazumi, Seki, Tetsuya, Fujiwara, Kenshu, Yasumoto, Takeshi

“…Two new analogs of the human lethal toxin polycavernoside A, polycavernoside C and C2 (0.1–0.2 mg for each), were isolated from the red alga, Gracilaria…”
Get full text

A conformational restriction approach to the development of dual inhibitors of acetylcholinesterase and serotonin transporter as potential agents for Alzheimer's disease by Toda, Narihiro, Tago, Keiko, Marumoto, Shinji, Takami, Kazuko, Ori, Mayuko, Yamada, Naho, Koyama, Kazuo, Naruto, Shunji, Abe, Kazumi, Yamazaki, Reina, Hara, Takao, Aoyagi, Atsushi, Abe, Yasuyuki, Kaneko, Tsugio, Kogen, Hiroshi

“…Alzheimer's disease (AD) has been treated with acetylcholinesterase (AChE) inhibitors such as donepezil. However, the clinical usefulness of AChE inhibitors is…”
Get full text

Pharmacological Characterization of RS-1259, an Orally Active Dual Inhibitor of Acetylcholinesterase and Serotonin Transporter, in Rodents: Possible Treatment of Alzheimer’s Disease by Abe, Yasuyuki, Aoyagi, Atsushi, Hara, Takao, Abe, Kazumi, Yamazaki, Reina, Kumagae, Yoshihiro, Naruto, Shunji, Koyama, Kazuo, Marumoto, Shinji, Tago, Keiko, Toda, Narihiro, Takami, Kazuko, Yamada, Naho, Ori, Mayuko, Kogen, Hiroshi, Kaneko, Tsugio

“…A dual inhibitor of acetylcholinesterase (AChE) and serotonin transporter (SERT), RS-1259 (4-[1S)-methylamino-3-(4-nitrophenoxy)]propylphenyl…”
Get full text

Design and Synthesis of Dual Inhibitors of Acetylcholinesterase and Serotonin Transporter Targeting Potential Agents for Alzheimer's Disease by Kogen, Hiroshi, Toda, Narihiro, Tago, Keiko, Marumoto, Shinji, Takami, Kazuko, Ori, Mayuko, Yamada, Naho, Koyama, Kazuo, Naruto, Shunji, Abe, Kazumi, Yamazaki, Reina, Hara, Takao, Aoyagi, Atsushi, Abe, Yasuyuki, Kaneko, Tsugio

“…Highly efficient acetylcholinesterase (AChE) and serotonin transporter (SERT) dual inhibitors, (S)-4 and (R)-13 were designed and synthesized on the basis of…”
Get full text

Design, synthesis and structure–Activity relationships of dual inhibitors of acetylcholinesterase and serotonin transporter as potential agents for Alzheimer's disease by Toda, Narihiro, Tago, Keiko, Marumoto, Shinji, Takami, Kazuko, Ori, Mayuko, Yamada, Naho, Koyama, Kazuo, Naruto, Shunji, Abe, Kazumi, Yamazaki, Reina, Hara, Takao, Aoyagi, Atsushi, Abe, Yasuyuki, Kaneko, Tsugio, Kogen, Hiroshi

“…We have designed and synthesized a dual inhibitor of acetylcholinesterase (AChE) and serotonin transporter (SERT) as a novel class of treatment drugs for…”
Get full text

Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant by Suzuki, Rigel, Yamasoba, Daichi, Kimura, Izumi, Wang, Lei, Kishimoto, Mai, Ito, Jumpei, Morioka, Yuhei, Nao, Naganori, Nasser, Hesham, Uriu, Keiya, Kosugi, Yusuke, Tsuda, Masumi, Orba, Yasuko, Sasaki, Michihito, Shimizu, Ryo, Kawabata, Ryoko, Yoshimatsu, Kumiko, Asakura, Hiroyuki, Nagashima, Mami, Sadamasu, Kenji, Yoshimura, Kazuhisa, Sawa, Hirofumi, Ikeda, Terumasa, Irie, Takashi, Matsuno, Keita, Tanaka, Shinya, Fukuhara, Takasuke, Sato, Kei

“…The emergence of the Omicron variant of SARS-CoV-2 is an urgent global health concern 1 . In this study, our statistical modelling suggests that Omicron has…”
Get full text

Mechanisms of action and resistance in histone methylation-targeted therapy by Yamagishi, Makoto, Kuze, Yuta, Kobayashi, Seiichiro, Nakashima, Makoto, Morishima, Satoko, Kawamata, Toyotaka, Makiyama, Junya, Suzuki, Kako, Seki, Masahide, Abe, Kazumi, Imamura, Kiyomi, Watanabe, Eri, Tsuchiya, Kazumi, Yasumatsu, Isao, Takayama, Gensuke, Hizukuri, Yoshiyuki, Ito, Kazumi, Taira, Yukihiro, Nannya, Yasuhito, Tojo, Arinobu, Watanabe, Toshiki, Tsutsumi, Shinji, Suzuki, Yutaka, Uchimaru, Kaoru

“…Epigenomes enable the rectification of disordered cancer gene expression, thereby providing new targets for pharmacological interventions. The clinical utility…”
Get full text

De Novo Genome Assembly of Japanese Black Cattle as Model of an Economically Relevant Animal by Sasaki, Shinji, Haga, Yasuhiko, Wakaguri, Hiroyuki, Abe, Kazumi, Suzuki, Yutaka

“…A genetic analysis of Japanese Black cattle using short reads and guided by the reference genome from Western breeds would miss the structural variation and/or…”
Get more information

Complete genome sequence and bioinformatics analysis of nine Egyptian females with clinical information from different geographic regions in Egypt by ElHefnawi, Mahmoud, Hegazy, Elsayed, Elfiky, Asmaa, Jeon, Yeonsu, Jeon, Sungwon, Bhak, Jong, Mohamed Metwally, Fateheya, Sugano, Sumio, Horiuchi, Terumi, Kazumi, Abe, Blazyte, Asta

“…•We reported and analyzed the whole genomes of nine Egyptian females from different regions.•A total 12 SNPs were shared in most of subjects.•mtDNA mutation…”
Get full text

Facility wastewater monitoring as an effective tool for pandemic infection control: An experience in COVID-19 pandemic with long-term monitoring by Tateishi, Shoko, Hamada, Kensuke, Emoto, Noriko, Abe, Kazumi, Abe, Koichi, Kawasaki, Yuki, Sunohara, Mitsuhiro, Moriya, Kyoji, Katayama, Hiroyuki, Tsutsumi, Takeya, Murakami, Yoshinori, Suzuki, Yutaka, Yotsuyanagi, Hiroshi, Yanagimoto, Shintaro

“…Since the first report of a novel coronavirus infection caused by SARS-CoV-2 in late 2019, the infection has spread rapidly and had a significant impact on our…”
Get full text

Durable Clinical Impacts and Mechanisms of Action and Resistance in EZH1/2-Targeting Epigenetic Therapy by Yamagishi, Makoto, Kuze, Yuta, Nakashima, Makoto, Kobayashi, Seiichiro, Morishima, Satoko, Kawamata, Toyotaka, Makiyama, Junya, Abe, Kazumi, Imamura, Kiyomi, Watanabe, Eri, Tsuchiya, Kazumi, Yasumatsu, Isao, Takayama, Gensuke, Ito, Kazumi, Nannya, Yasuhito, Tojo, Arinobu, Watanabe, Toshiki, Tsutsumi, Shinji, Suzuki, Yutaka, Uchimaru, Kaoru

Get full text

学校薬剤師業務における絶対湿度利用の提言 by 植芝, 亮太, 植芝, 理恵子, 安倍, 一実, 金月, 真央, 伊藤, 美咲

“…「緒言」 われわれは教室内の湿度管理について, 相対湿度(relative humidity;RH)を用いてきた. 文部科学省作成の学校環境衛生管理マニュアルでは「30%以上, 80%以下であることが望ましい」,…”
Get full text

Efficacy of a novel training food based on the process model of feeding for mastication and swallowing: A study among dysphagia patients by Shibata, Seiko, Kagaya, Hitoshi, Tanaka, Shinichiro, Fujii, Wataru, Nakagawa, Kazuharu, Matsuo, Koichiro, Abe, Kazumi, Ishibashi, Naoto, Inamoto, Yoko, Saitoh, Eiichi

Get full text

Pharmacological Characterization of RS-1259, an Orally Active Dual Inhibitor of Acetylcholinesterase and Serotonin Transporter, in Rodents: Possible Treatment of Alzheimer’s Disease by Abe, Yasuyuki, Aoyagi, Atsushi, Hara, Takao, Abe, Kazumi, Yamazaki, Reina, Kumagae, Yoshihiro, Naruto, Shunji, Koyama, Kazuo, Marumoto, Shinji, Tago, Keiko, Toda, Narihiro, Takami, Kazuko, Yamada, Naho, Ori, Mayuko, Kogen, Hiroshi, Kaneko, Tsugio

“…A dual inhibitor of acetylcholinesterase (AChE) and serotonin transporter (SERT), RS-1259 (4-[1S)-methylamino-3-(4-nitrophenoxy)]propylphenyl…”
Get full text

Efficacy of a novel training food based on the process model of feeding for mastication and swallowing ― A preliminary study in elderly individuals living at a residential facility by Nakagawa, Kazuharu, Matsuo, Koichiro, Shibata, Seiko, Inamoto, Yoko, Ito, Yuriko, Abe, Kazumi, Ishibashi, Naoto, Fujii, Wataru, Saitoh, Eiichi

Get full text

Suggestion to School Pharmacists to Utilize Absolute Humidity Parameter for Maintaining Air-Conditioning by Ueshiba, Ryota, Ueshiba, Rieko, Abe, Kazumi, Kingetsu, Mao, Ito, Misaki

“…One of the major roles of a school pharmacist is to maintain adequate air conditioning in the school to prevent the spread of infectious diseases. Influenza,…”
Get full text

Two elderly patients with thoracic herpetic pain and post herpetic neuralgia treated with continuous thoracic sympathetic ganglion block through a placed catheter by Takeda, T, Iida, H, Ohta, S, Oda, A, Abe, K, Oohata, H, Akamatsu, S, Dohi, S

“…Epidural block is very useful in the treatment of herpetic pain and post herpetic neuralgia. However, in the elderly patients with cardiac disease or diabetes…”
Get more information