Search Results - "Abdulwahab A. Oyouni, Atif"
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Interleukin-10 as Covid-19 biomarker targeting KSK and its analogues: Integrated network pharmacology
Published in PloS one (29-03-2023)“…COVID-19 caused by the SARS-CoV-2 virus is widespread in all regions, and it disturbs host immune system functioning leading to extreme inflammatory reaction…”
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2
Avocado Seeds-Mediated Alleviation of Cyclosporine A-Induced Hepatotoxicity Involves the Inhibition of Oxidative Stress and Proapoptotic Endoplasmic Reticulum Stress
Published in Molecules (Basel, Switzerland) (14-11-2022)“…Previous studies reported disrupted hepatic function and structure following the administration of cyclosporine A (CsA) in humans and animals. Recently, we…”
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3
Association of SNPs within TMPRSS6 and BMP2 genes with iron deficiency status in Saudi Arabia
Published in PloS one (15-11-2021)“…Globally, iron-deficiency anemia (IDA) remains a major health obstacle. This health condition has been identified in 47% of pre-school students (aged 0 to 5…”
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4
Ameliorative Effects of Camel Milk and Its Exosomes on Diabetic Nephropathy in Rats
Published in Membranes (Basel) (28-10-2022)“…Contradictory results were obtained regarding the effects of extracellular vesicles such as exosomes (EXOs) on diabetes and diabetic nephropathy (DN). Some…”
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Toxicity, Safety, and Efficacy Studies on Mesenchymal Stem Cells Derived from Decidua basalis in Wistar Albino Rats by Intravenous and Subcutaneous Routes
Published in Current issues in molecular biology (06-09-2022)“…Ex vivo expanded decidua-basalis(DB)-derived mesenchymal stem cells (MSCs) obtained from single donors have demonstrated therapeutic benefits in in vitro and…”
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Phytochemical Composition and Bioactivities of Some Hydrophytes: Antioxidant, Antiparasitic, Antibacterial, and Anticancer Properties and Mechanisms
Published in Plants (Basel) (01-08-2024)“…Few researches have explored the production of pharmaceuticals from aquatic plants. Therefore, this study explored, for the first time, the phytochemical…”
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Human papillomavirus in cancer: Infection, disease transmission, and progress in vaccines
Published in Journal of infection and public health (01-04-2023)“…Human papillomaviruses (HPVs) infect epithelial cells of human beings, and their replication cycle is associated with epithelial differentiation. More than 200…”
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Biological and genetic basis of various human genetic disorders and the application of biological and genetic markers
Published in Journal of King Saud University. Science (01-06-2022)“…The antigens of the ABO blood group systems are expressed on the membrane of the red blood cells and on the surface of several pathological and normal cells…”
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In silico investigations identified Butyl Xanalterate to competently target CK2α (CSNK2A1) for therapy of chronic lymphocytic leukemia
Published in Scientific reports (21-10-2022)“…Chronic lymphocytic leukemia (CLL) is an incurable malignancy of B-cells. In this study, bioinformatics analyses were conducted to identify possible pathogenic…”
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10
BARD1 mystery: tumor suppressors are cancer susceptibility genes
Published in BMC cancer (01-06-2022)“…The full-length BRCA1-associated RING domain 1 (BARD1) gene encodes a 777-aa protein. BARD1 displays a dual role in cancer development and progression as it…”
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Correction: Association of SNPs within TMPRSS6 and BMP2 genes with iron deficiency status in Saudi Arabia
Published in PloS one (02-07-2024)“…[This corrects the article DOI: 10.1371/journal.pone.0257895.]…”
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Zingiberene exerts chemopreventive activity against 7,12‐dimethylbenz(a)anthracene‐induced breast cancer in Sprague‐Dawley rats
Published in Journal of biochemical and molecular toxicology (01-10-2022)“…Breast cancer is the primary cause of cancer‐related death in females, wherein increased mortality of breast cancer patients is recorded worldwide. Zingiberene…”
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13
New insight into strategies used to develop long-acting G-CSF biologics for neutropenia therapy
Published in Frontiers in oncology (05-01-2023)“…Over the last 20 years, granulocyte colony-stimulating factors (G-CSFs) have become the major therapeutic option for the treatment of patients with…”
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14
Nitric Oxide Synthase Potentiates the Resistance of Cancer Cell Lines to Anticancer Chemotherapeutics
Published in Anti-cancer agents in medicinal chemistry (01-01-2022)“…Despite the advancement in the fields of medical science and molecular biology, cancer is still the leading cause of death worldwide. Chemotherapy is a choice…”
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15
Developing a Multimodal Model for Detecting Higher-Grade Prostate Cancer Using Biomarkers and Risk Factors
Published in BioMed research international (10-06-2022)“…A technique to predict crucial clinical prostate cancer (PC) is desperately required to prevent diagnostic errors and overdiagnosis. To create a multimodal…”
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Antiulcer activity of proanthocyanidins is mediated via suppression of oxidative, inflammatory, and apoptotic machineries
Published in Journal of food biochemistry (01-02-2022)“…Gastric ulcer (GU) is a lesion in the gastric mucosa associated with excessive oxidative damage, inflammatory response, apoptotic events, and irritation which…”
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Camels' biological fluids contained nanobodies: promising avenue in cancer therapy
Published in Cancer cell international (07-09-2022)“…Cancer is a major health concern and accounts for one of the main causes of death worldwide. Innovative strategies are needed to aid in the diagnosis and…”
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In Silico Identification of Hub Genes as Observing Biomarkers for Gastric Cancer Metastasis
Published in Evidence-based complementary and alternative medicine (2022)“…Perception of hub genes engaged in metastatic gastric cancer (mGC) promotes novel ways to diagnose and treat the illness. The goal of this investigation is to…”
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Stem Cell Applications for Treatment of Cancer and Autoimmune Diseases: Its Promises, Obstacles, and Future Perspectives
Published in Technology in Cancer Research & Treatment (01-01-2018)“…Since the original discovery of stem cells, a new era of promising results has emerged in the clinical application of stem cells for the treatment of several…”
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Immunosuppressant drug tacrolimus induced mitochondrial nephrotoxicity, modified PCNA and Bcl-2 expression attenuated by Ocimum basilicum L. in CD1 mice
Published in Toxicology reports (01-01-2018)“…[Display omitted] •Tacrolimus (TAC), an immunosuppressant drug has been demonstrated to augment free radical production.•It increased serum creatinine, BUN and…”
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