Monodisperse Gold Nanoparticles: A Review on Synthesis and Their Application in Modern Medicine

Monodisperse Gold Nanoparticles: A Review on Synthesis and Their Application in Modern Medicine

Gold nanoparticles (AuNPs) are becoming increasingly popular as drug carriers due to their unique properties such as size tenability, multivalency, low toxicity and biocompatibility. AuNPs have physical features that distinguish them from bulk materials, small molecules and other nanoscale particles...

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Bibliographic Details
Published in:International journal of molecular sciences Vol. 23; no. 13; p. 7400
Main Authors: Dheyab, Mohammed Ali, Aziz, Azlan Abdul, Moradi Khaniabadi, Pegah, Jameel, Mahmood S, Oladzadabbasabadi, Nazila, Mohammed, Selwan Abduljabbar, Abdullah, Raja Saleh, Mehrdel, Baharak
Format: Journal Article
Language:English
Published: Switzerland MDPI AG 02-07-2022
MDPI
Subjects:
Biocompatibility
Biomedical materials
Cancer therapies
Drug Carriers
Drug delivery
Free radicals
Gold
imaging
Medical research
Metal Nanoparticles - therapeutic use
monodisperse AuNPs
Nanoparticles
Radiation
Review
Surface chemistry
surface modification
theranostic
Therapeutic applications
therapy
Toxicity
monodisperse AuNPs
theranostic
imaging
surface modification
therapy
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Summary:Gold nanoparticles (AuNPs) are becoming increasingly popular as drug carriers due to their unique properties such as size tenability, multivalency, low toxicity and biocompatibility. AuNPs have physical features that distinguish them from bulk materials, small molecules and other nanoscale particles. Their unique combination of characteristics is just now being fully realized in various biomedical applications. In this review, we focus on the research accomplishments and new opportunities in this field, and we describe the rising developments in the use of monodisperse AuNPs for diagnostic and therapeutic applications. This study addresses the key principles and the most recent published data, focusing on monodisperse AuNP synthesis, surface modifications, and future theranostic applications. Moving forward, we also consider the possible development of functionalized monodisperse AuNPs for theranostic applications based on these efforts. We anticipate that as research advances, flexible AuNPs will become a crucial platform for medical applications.
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content type line 23
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms23137400