Search Results - "Abdoul, Johan"
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Shear Forces Induced Platelet Clearance Is a New Mechanism of Thrombocytopenia
Published in Circulation research (27-10-2023)“…Thrombocytopenia has been consistently described in patients with extracorporeal membrane oxygenation (ECMO) and associated with poor outcome. However, the…”
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Shear Force-Induced Platelet Clearance Is a New Mechanism of Thrombocytopenia
Published in Circulation research (27-10-2023)“…BACKGROUND: Thrombocytopenia has been consistently described in patients with extracorporeal membrane oxygenation (ECMO) and associated with poor outcome…”
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Rivaroxaban pharmacodynamics in healthy volunteers evaluated with thrombin generation and the active protein C system: Modeling and assessing interindividual variability
Published in Journal of thrombosis and haemostasis (01-10-2019)“…Background Rivaroxaban is a direct factor Xa inhibitor with substantial inter‐individual pharmacokinetic (PK) variability. Pharmacodynamic (PD) variability,…”
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Induced forms of α2-macroglobulin neutralize heparin and direct oral anticoagulant effects
Published in International journal of biological macromolecules (01-08-2021)“…Alpha2-macroglobulin (α2M) is a physiological macromolecule that facilitates the clearance of many proteinases, cytokines and growth factors in human. Here, we…”
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Aortic endothelial cells response to pulsatile vs. continuous flow at high shear stress
Published in Archives of cardiovascular diseases (01-06-2024)“…Severe heart failure leads to the implantation of a left ventricular assist device (LVAD) in patients waiting for a heart transplant. These pumps induce a…”
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Study of thrombin generation with St Genesia to evaluate xaban pharmacodynamics: Analytical performances over 18 months
Published in International Journal of Laboratory Hematology (01-08-2021)“…Introduction ST Genesia is a new automated system enabling quantitative standardized evaluation of thrombin generation (TG), for example, in patients receiving…”
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