Search Results - "Abdelzaher, Walaa Yehia"

Vinpocetine ameliorates L-arginine induced acute pancreatitis via Sirt1/Nrf2/TNF pathway and inhibition of oxidative stress, inflammation, and apoptosis by Abdelzaher, Walaa Yehia, Ahmed, Sabreen Mahmoud, Welson, Nermeen N, Marraiki, Najat, Batiha, Gaber El-Saber, Kamel, Maha Yehia

“…Acute pancreatitis (AP) is a common severe critical illness with a high mortality rate. We aimed to study the effect of vinpocetine (Vinpo) in the treatment of…”
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Retraction Notice to “Vinpocetine ameliorates L-arginine induced acute pancreatitis via Sirt1/Nrf2/TNF pathway and inhibition of oxidative stress, inflammation, and apoptosis” [Biomed. Pharmacother. 133 (2020) 110976] by Abdelzaher, Walaa Yehia, Ahmed, Sabreen Mahmoud, Welson, Nermeen N., Marraiki, Najat, Batiha, Gaber El-Saber, Kamel, Maha Yehia

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The protective effect of vinpocetine against Estradiol-benzoate induced cervical hyperkeratosis in female rats via modulation of SIRT1/Nrf2, and NLRP3 inflammasome by Rofaeil, Remon R., Mohyeldin, Reham H., Sharata, Ehab E., Attya, Mina Ezzat, Essawy, Hany, Ibrahim, Osama A., Abdelzaher, Walaa Yehia

“…The current study was assigned to determine the putative preventive role of vinpocetine (VIN) in cervical hyperkeratosis (CHK) in female rats. Estradiol…”
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Diacerein protects rats with liver ischemia/reperfusion damage: Down-regulation of TLR4/ NFκ-B signaling pathway by Ibrahim, Mohamed Abdellah, Abdelzaher, Walaa Yehia, Ibrahim, Yasmine F., Ahmed, Amira F., Welson, Nermeen N., Al-Rashed, Sarah, Batiha, Gaber El-Saber, Abdel-Aziz, Asmaa Mohamed

“…[Display omitted] •Liver ischemia reperfusion injury is an unavoidable problem, still a challenge.•Diacerein exhibits anti-inflammatory, anti-apoptotic and…”
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Diacerein ameliorates letrozole-induced polycystic ovarian syndrome in rats by Ibrahim, Yasmine F., Alorabi, Mohammed, Abdelzaher, Walaa Yehia, Toni, Nisreen DM, Thabet, Khaled, Hegazy, AbdelRahman, Bahaa, Haitham Ahmed, Batiha, Gaber El-Saber, Welson, Nermeen N., Morsy, Mohamed A., Venugopala, Katharigatta N., Abdel-Aziz, Asmaa Mohamed

“…Polycystic ovary syndrome (PCOS) is the most common gynaecological endocrine disease that causes anovulatory infertility. The current study aimed to explore…”
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Atorvastatin protects against cyclophosphamide-induced thyroid injury in rats via modulation of JNK/ ERK/ p38 MAPK signaling pathway by Yehia Abdelzaher, Walaa, A. Abdel-Gaber, Seham, Atef Fawzy, Michael, Hamid Sayed Abo Bakr Ali, Abdel, Ezzat Attya, Mina, Geddawy, Ayman

“…•Atorvastatin prevented cyclophosphamide-induced hypothyroidism.•Atorvastatin has antioxidant and anti-inflammatory activity.•Atorvastatin modulated JNK/…”
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Dapsone Ameliorates Isoproterenol-Induced Myocardial Infarction via Nrf2/ HO-1; TLR4/ TNF-α Signaling Pathways and the Suppression of Oxidative Stress, Inflammation, and Apoptosis in Rats by Abdelzaher, Walaa Yehia, Ahmed, Sabreen Mahmoud, Welson, Nermeen N., Alsharif, Khalaf F., Batiha, Gaber El-Saber, Labib, Dina A. Aly

“…Myocardial infarction (MI) is a critical condition that can happen with high doses or rapid termination of beta blockers therapy. The study aimed to evaluate…”
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Rivastigmine ameliorates indomethacin experimentally induced gastric mucosal injury via activating α7nAChR with inhibiting oxidative stress and apoptosis by Khalaf, Hanaa M., Ahmed, Sabreen M., Welson, Nermeen N., Abdelzaher, Walaa Yehia

“…The current study aimed to investigate the potential ameliorative role of Rivastigmine (RIVA), the anti‐Alzheimer drug, against the gastric mucosal injury…”
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Rupatadine ameliorated ulcerative colitis in rats via modulation of platelet-activatiweng factor/interleukin-6/vascular endothelial growth factor signalling pathway by Ibrahim, Mohamed A, Abdelmonaem, Alyaa Abdelfattah, Abdel-Gaber, Seham A, Hafez, Heba M, Abdel Hafez, Sara Mohamed Naguib, Yehia Abdelzaher, Walaa

“…This study aimed to analyse the potential effect of rupatadine (RUP) on ulcerative colitis (UC) induced by acetic acid (AA). Forty male adult Wistar rats were…”
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Diacerein modulates TLR4/ NF‐κB/IL‐1β and TRPC1/CHOP signalling pathways in gentamicin‐induced parotid toxicity in rats by Ali, Dalia Mohamed, Mahmoud, Mohamed H., Rifaai, Rehab Ahmed, Fawzy, Michael Atef, Atta, Medhat, Welson, Nermeen N., Batiha, Gaber El‐Saber, Alexiou, Athanasios, Papadakis, Marios, Abdelzaher, Walaa Yehia

“…The present study aimed to identify the possible protective effect of diacerein (DIA) on gentamicin (GNT)‐induced parotid toxicity in rats. DIA was…”
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Cardioprotective effect of Tofisopam against isoprenaline-induced myocardial infarction in rats via modulation of NLRP3\IL-1β\caspase-1 pathway by Abdelmonaem, Alyaa Abdelfattah, Abdel-Aziz, Asmaa Mohamed, Ibrahim, Yasmine F, Abdelzaher, Walaa Yehia, Amgad Mohammed, Nada, Marey, Heba, S Taghian, Asmaa, Setouhi, Amr, Radi, Ashraf, Ahmed, Sara M

“…Cardiovascular diseases (CVDs) are a leading cause of morbidity and mortality worldwide. Ischemic heart diseases, particularly acute myocardial infarction…”
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Protective effect of mirtazapine against acetic acid-induced ulcerative colitis in rats: Role of NLRP3 inflammasome pathway by Hafez, Heba M., Ibrahim, Mohamed A., Yehia Abdelzaher, Walaa, Gad, Alyaa A., Mohammed Naguib Abdel Hafez, Sara, Abdel-Gaber, Seham A.

“…•Mirtazapine prevented the acetic acid induced colonic damage in rats.•Mirtazapine has antioxidant and anti-inflammatory activity.•Mirtazapine modulates…”
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Protective mechanisms of telmisartan against hepatic ischemia/reperfusion injury in rats may involve PPARγ-induced TLR4/NF-κB suppression by Morsy, Mohamed A., Abdel-Gaber, Seham A., Rifaai, Rehab A., Mohammed, Mostafa M., Nair, Anroop B., Abdelzaher, Walaa Yehia

“…Hepatic ischemia-reperfusion (I/R) is an important cause of liver damage in many clinical situations. Toll-like receptor 4 (TLR4)/nuclear factor-kappa B…”
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Synthesis, Characterization, and In Vivo Study of Some Novel 3,4,5-Trimethoxybenzylidene-hydrazinecarbothioamides and Thiadiazoles as Anti-Apoptotic Caspase-3 Inhibitors by Mostafa, Sara M, Aly, Ashraf A, Bräse, Stefan, Nieger, Martin, Abdelhafez, Sara Mohamed Naguib, Abdelzaher, Walaa Yehia, Abdelhafez, El-Shimaa M N

“…The present study aims to discover novel derivatives as antiapoptotic agents and their protective effects against renal ischemia/reperfusion. Therefore, a…”
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Efficacy of vitamin E in protection against methotrexate induced placental injury in albino rats by Hafez, Sara Mohamed Naguib Abdel, Elbassuoni, Eman, Abdelzaher, Walaa Yehia, Welson, Nermeen N., Batiha, Gaber El-Saber, Alzahrani, Khalid J., Abdelbaky, Fatma Alzhraa Fouad

“…Methotrexate (MXT) is a chemotherapeutic drug that has been used in a wide range of clinical practices. Unfortunately, the administration of MXT during…”
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Hypoxia inducible factor-1α (HIF-1α) as an early predictor of acute hydrogen cyanamide (Dormex) poisoning by Rezk, Meriam N.N., Beshreda, Gerges M., Meshref, Dalia Abdelrahman, Abdelzaher, Walaa Yehia, Batiha, Gaber El-Saber, Hafiz, Amin A., Althumairy, Duaa, Aljarba, Nada H., Welson, Nermeen N.

“…Hydrogen cyanamide (Dormex) is a plant growth regulator that is classified as a highly toxic poison. There are no definite investigations to help in its…”
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Protective effect of rivastigmine against lung injury in acute pancreatitis model in rats via Hsp 70/IL6/ NF-κB signaling cascade by Yehia Kamel, Maha, Zekry Attia, Josef, Mahmoud Ahmed, Sabreen, Hassan Saeed, Zainab, Welson, Nermeen N, Yehia Abdelzaher, Walaa

“…Acute lung injury (ALI) that develops as a result of AP can progress to acute respiratory distress syndrome. Some hypotheses are proposed to explain the…”
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Design, Synthesis, Molecular Docking, Antiapoptotic and Caspase-3 Inhibition of New 1,2,3-Triazole/ Bis -2(1 H )-Quinolinone Hybrids by El-Sheref, Essmat M, Aly, Ashraf A, Alshammari, Mohammed B, Brown, Alan B, Abdel-Hafez, Sara Mohamed Naguib, Abdelzaher, Walaa Yehia, Bräse, Stefan, Abdelhafez, ElShimaa M N

“…A series of novel 1,2,3-triazoles hybridized with two quinolin-2-ones, was designed and synthesized through click reactions. The structures of the synthesized…”
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Rivaroxaban Modulates TLR4/Myd88/NF-Kβ Signaling Pathway in a Dose-Dependent Manner With Suppression of Oxidative Stress and Inflammation in an Experimental Model of Depression by Abdelzaher, Walaa Yehia, Mohammed, Hanaa H., Welson, Nermeen N., Batiha, Gaber El-Saber, Baty, Roua S., Abdel-Aziz, Asmaa Mohamed

“…Depression is a common mental illness leading to upset or anxiety, with a high incidence rate in the world. Depression can lead to suicidal thoughts and…”
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Amelioration of estrogen-induced endometrial hyperplasia in female rats by hemin via heme-oxygenase-1 expression, suppression of iNOS, p38 MAPK, and Ki67 by Ali, Fatma F, Abdelzaher, Walaa Yehia, Ibrahim, Randa Ahmed, Elroby Ali, Doaa Mohamed

“…Although heme oxygenase-1 (HO-1) is part of an endogenous defense system implicated in the homeostatic response, its role in cell proliferation and tumor…”
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