Search Results - "Abdelrahman, Maha M"
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Simultaneous determination of Cinnarizine and Domperidone by area under curve and dual wavelength spectrophotometric methods
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (01-09-2013)“…•New spectrophotometric determination of Cinnarizine and Domperidone.•Area under curve method is simple with minimal sample and data manipulation.•Dual…”
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2
Greenness assessment of UPLC/MS/MS method for determination of two antihypertensive agents and their harmful impurities with ADME/TOX profile study
Published in Scientific reports (07-11-2023)“…Hypertension is described by the world health organization (WHO) as a serious medical problem that significantly affects the heart, brain and kidneys. It is a…”
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3
Development and validation of a stability indicating RP-HPLC-DAD method for the determination of bromazepam
Published in PloS one (10-03-2021)“…A reliable, selective and sensitive stability-indicating RP-HPLC assay was established for the quantitation of bromazepam (BMZ) and one of the degradant and…”
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4
High Performance Thin Layer Chromatography (HPTLC) Analysis of Anti-Asthmatic Combination Therapy in Pharmaceutical Formulation: Assessment of the Method's Greenness and Blueness
Published in Pharmaceuticals (Basel, Switzerland) (29-07-2024)“…A cost-effective, selective, sensitive, and operational TLC-densitometric approach has been adapted for the concurrent assay of Hydroxyzine Hydrochloride…”
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5
Ecofriendly single-step HPLC and TLC methods for concurrent analysis of ternary antifungal mixture in their pharmaceutical products
Published in BMC chemistry (01-12-2023)“…Two accurate, sensitive, and selective methods for simultaneous determination of miconazole nitrate (MIC), nystatin (NYS), and metronidazole (MET) in pure…”
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AQbD TLC-densitometric method approach along with green fingerprint and whiteness assessment for quantifying two combined antihypertensive agents and their impurities
Published in BMC chemistry (22-01-2024)“…Preserving the environment, reducing the amount of waste resulting from chemical trials, and reducing the amount of energy consumed have currently become a…”
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Chromatographic methods development, validation and degradation characterization of the antithyroid drug Carbimazole
Published in Biomedical chromatography (01-04-2019)“…The current paper reports the development and validation of stability‐indicating HPLC and HPTLC methods for the separation and quantification of main impurity…”
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8
Appraisal of the greenness profile of a chromatographic method for the simultaneous estimation of carbamazepine and oxcarbazepine, along with two potential impurities and three formulation excipients
Published in RSC advances (17-02-2021)“…Structurally related carbamazepine (CBZ) and oxcarbazepine (OX) are two of the most commonly used antipsychotic drugs. The main impurities of CBZ, as described…”
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Nanoparticle-enhanced in-line potentiometric ion sensor for point-of-care diagnostics for tropicamide abuse in biological fluid
Published in Analytica chimica acta (01-02-2022)“…Point of care (POC), also identified as on-site testing, has evolved as a rapid and accurate technique for drug of abuse screening and analysis. The aim of…”
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10
Harnessing spectrophotometry resolution power for determining ternary mixture for respiratory disorders treatment in their pharmaceutical formulation
Published in PloS one (07-10-2024)“…A ternary mixture incorporating Hydroxyzine hydrochloride (HYX), Ephedrine hydrochloride (EPH) and Theophylline (THP) frequently prescribed for the treatment…”
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11
Selective spectrophotometric methods for determination of ternary mixture with overlapping spectra: A comparative study
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (24-04-2014)“…[Display omitted] •Selective determination of ternary mixture with severe spectral overlap.•More convenient and easier spectrophotometric methods are…”
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12
In-vitro/in-vivo comparison of inhaled salbutamol dose delivered by jet nebulizer, vibrating mesh nebulizer and metered dose inhaler with spacer during non-invasive ventilation
Published in Experimental lung research (01-02-2017)“…Background: Patients receiving noninvasive ventilation (NIV) may benefit from medical aerosol, but most guidance on dosing with different aerosol devices is…”
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13
Lipophilicity study of different cephalosporins: Computational prediction of minimum inhibitory concentration using salting-out chromatography
Published in Journal of pharmaceutical and biomedical analysis (30-11-2021)“…•A green SOTLC method was applied to examine the retention parameters and lipophilicity of seven cepholosporins.•QSAR and QSPR models were constructed using…”
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14
Analysis of Carbamazepine, Oxcarbazepine, Their Impurities, and Non-Labeled Interfering Substances by Stability-indicating UPLC/MS/MS Method: Studying the Method’s Greenness Profile
Published in Chromatographia (01-11-2018)“…Carbamazepine (CBZ) and oxcarbazepine (OX) are highly effective anti-psychotic drugs. In USP, it is stated that CBZ has several impurities including,…”
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15
Comparative Chemometric Manipulations of UV-Spectrophotometric Data for the Efficient Resolution and Determination of Overlapping Signals of Cyclizine and Its Impurities in Its Pharmaceutical Preparations
Published in Journal of AOAC International (22-12-2022)“…Cyclizine (CYZ), a commonly used antiemetic drug, has two pharmacopeial toxic impurities, 1-methylpiperazine (MPZ) and diphenylmethanol (DPM). When CYZ…”
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16
Different stability‐indicating chromatographic methods for specific determination of paracetamol, dantrolene sodium, their toxic impurities and degradation products
Published in Biomedical chromatography (01-09-2019)“…A well‐known analgesic (paracetamol, PAR) and skeletal muscle relaxant [dantrolene sodium (DNS)] have been analyzed without interference from their toxic…”
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Validated spectrofluorometric determination of hypoglycemic combination, in pure form and pharmaceutical formulation using 9,10-phenanthraquinone reagent
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (15-02-2021)“…The aim of this work is to develop and validate a simple, rapid, highly sensitive and selective spectrofluorometric method for determination of Metformin HCl…”
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18
Quality by design approach for green HPLC method development for simultaneous analysis of two thalassemia drugs in biological fluid with pharmacokinetic study
Published in RSC advances (05-05-2022)“…This work implements a combined experimental approach of analytical quality-by-design (AQbD) and green analytical chemistry (GAC) to develop an HPLC method for…”
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19
Determination of sofosbuvir with two co-administered drugs; paracetamol and DL-methionine by two chromatographic methods. Application to a pharmacokinetic study
Published in Bioanalysis (01-03-2019)“…Two rapid and sensitive chromatographic methods have been developed and validated for simultaneous analysis of sofosbuvir (SOF) in rat plasma with two…”
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20
Modelling of in-vitro and in-vivo performance of aerosol emitted from different vibrating mesh nebulisers in non-invasive ventilation circuit
Published in European journal of pharmaceutical sciences (15-01-2017)“…Substituting nebulisers by another in non-invasive ventilation circuit (NIV) involves many process variables which must be adjusted to ensure patient optimum…”
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